ASD

ASD

Genome-wide predictions of autism-associated genes

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive patterns of behavior. ASD has a strong genetic basis but we still lack the full complement of autism-associated genes.

Here we present a genome-wide prediction of autism-associated genes based on known disease genes in the context of a human brain-specific gene interaction network.

Citation

Krishnan A*, Zhang R*, Yao V, Theesfeld CL, Wong AK, Tadych A, Volfovsky N, Packer A, Lash A, Troyanskaya OG.(2016) Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder. Nature Neuroscience.

Use the table below to explore brain-specific interactions between top-ranked ASD-genes, as well as ASD-associated cellular processes and pathways, aspects of the developing human brain, and recurrent copy-number variants (CNVs).

Rank ?Gene ?Standard ?Evidence ? Probability ? p-value ? q-value ? FMRP ?CHD8 ?TOP1 ?WNT ?MAPK ?PSD ?
ID ?Description ?Number of genes ?Score ?
GO:0048812 neuron projection morphogenesis 464 18.542564
GO:0048667 cell morphogenesis involved in neuron differentiation 452 18.476288
GO:0007409 axonogenesis 433 18.043269
GO:0007411 axon guidance 344 15.616034
GO:0007420 brain development 411 14.826659
GO:0060284 regulation of cell development 386 13.911159
GO:0051960 regulation of nervous system development 338 13.554088
GO:0007610 behavior 335 13.352139
GO:0050804 regulation of synaptic transmission 162 13.235143
GO:0031644 regulation of neurological system process 188 13.106371
GO:0051969 regulation of transmission of nerve impulse 176 13.06323
GO:0050767 regulation of neurogenesis 306 12.986747
GO:0045664 regulation of neuron differentiation 258 12.741936
GO:0030900 forebrain development 225 12.663138
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 488 11.92025
GO:0050890 cognition 136 11.447038
GO:0007611 learning or memory 125 11.077066
GO:0044057 regulation of system process 381 11.029702
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 494 10.947601
GO:0021537 telencephalon development 132 10.651404
GO:0048011 nerve growth factor receptor signaling pathway 218 10.491979
GO:0010769 regulation of cell morphogenesis involved in differentiation 146 10.405686
GO:0010975 regulation of neuron projection development 162 10.395471
GO:0006836 neurotransmitter transport 107 10.002215
GO:0007423 sensory organ development 337 9.998531
GO:0023057 negative regulation of signaling 484 9.917864
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 335 9.912436
GO:0045597 positive regulation of cell differentiation 379 9.906007
GO:0010648 negative regulation of cell communication 484 9.901926
GO:0007156 homophilic cell adhesion 139 9.749644
GO:0042391 regulation of membrane potential 163 9.749395
GO:0031344 regulation of cell projection organization 195 9.635304
GO:0007612 learning 68 9.436315
GO:0048167 regulation of synaptic plasticity 78 9.405564
GO:0007626 locomotory behavior 108 9.255874
GO:0021543 pallium development 80 9.056138
GO:0030001 metal ion transport 468 8.978456
GO:0048168 regulation of neuronal synaptic plasticity 43 8.7668
GO:0007269 neurotransmitter secretion 67 8.754203
GO:0007389 pattern specification process 343 8.732706
GO:0003001 generation of a signal involved in cell-cell signaling 116 8.709898
GO:0023061 signal release 116 8.709898
GO:0009968 negative regulation of signal transduction 447 8.699674
GO:0022604 regulation of cell morphogenesis 211 8.676006
GO:0021953 central nervous system neuron differentiation 90 8.669447
GO:0001505 regulation of neurotransmitter levels 97 8.648323
GO:0070647 protein modification by small protein conjugation or removal 405 8.608848
GO:0045761 regulation of adenylate cyclase activity 105 8.557688
GO:0046883 regulation of hormone secretion 152 8.52223
GO:0022603 regulation of anatomical structure morphogenesis 419 8.519487
GO:0010720 positive regulation of cell development 133 8.482464
GO:0031279 regulation of cyclase activity 108 8.479491
GO:0016568 chromatin modification 384 8.441444
GO:0060341 regulation of cellular localization 466 8.384752
GO:0051093 negative regulation of developmental process 394 8.330526
GO:0006140 regulation of nucleotide metabolic process 349 8.316318
GO:0045596 negative regulation of cell differentiation 320 8.297856
GO:0071495 cellular response to endogenous stimulus 365 8.288646
GO:0051339 regulation of lyase activity 110 8.255215
GO:0050770 regulation of axonogenesis 85 8.242686
GO:0030817 regulation of cAMP biosynthetic process 122 8.229552
GO:0045165 cell fate commitment 161 8.226607
GO:0048598 embryonic morphogenesis 377 8.173317
GO:0002791 regulation of peptide secretion 126 8.151537
GO:0090087 regulation of peptide transport 126 8.151537
GO:0015672 monovalent inorganic cation transport 317 8.141577
GO:0001654 eye development 216 8.120226
GO:0090276 regulation of peptide hormone secretion 124 8.117823
GO:0006813 potassium ion transport 156 8.115892
GO:0030814 regulation of cAMP metabolic process 123 8.114464
GO:0010721 negative regulation of cell development 91 8.084213
GO:0048638 regulation of developmental growth 83 8.066037
GO:0003002 regionalization 234 8.059711
GO:0048568 embryonic organ development 249 8.052682
GO:0030802 regulation of cyclic nucleotide biosynthetic process 132 8.043203
GO:0030808 regulation of nucleotide biosynthetic process 132 8.043203
GO:0030534 adult behavior 81 8.031442
GO:0030799 regulation of cyclic nucleotide metabolic process 137 7.921891
GO:0032870 cellular response to hormone stimulus 330 7.894876
GO:0048169 regulation of long-term neuronal synaptic plasticity 24 7.828424
GO:0048562 embryonic organ morphogenesis 172 7.737036
GO:0019933 cAMP-mediated signaling 118 7.717608
GO:0050796 regulation of insulin secretion 117 7.701945
GO:0043009 chordate embryonic development 390 7.662389
GO:0050769 positive regulation of neurogenesis 102 7.646875
GO:0009792 embryo development ending in birth or egg hatching 397 7.637994
GO:0051588 regulation of neurotransmitter transport 36 7.626989
GO:0019932 second-messenger-mediated signaling 312 7.624191
GO:0051046 regulation of secretion 357 7.623078
GO:0021761 limbic system development 57 7.552635
GO:0021954 central nervous system neuron development 36 7.530546
GO:0035295 tube development 319 7.527447
GO:0014047 glutamate secretion 17 7.474376
GO:0044087 regulation of cellular component biogenesis 241 7.472728
GO:0043010 camera-type eye development 183 7.452075
GO:0050768 negative regulation of neurogenesis 75 7.42478
GO:0021987 cerebral cortex development 54 7.413015
GO:0007215 glutamate signaling pathway 26 7.399446
GO:0051056 regulation of small GTPase mediated signal transduction 338 7.390997
GO:0009894 regulation of catabolic process 394 7.36491
GO:0008344 adult locomotory behavior 51 7.361097
GO:0001764 neuron migration 74 7.354689
GO:0001508 regulation of action potential 89 7.215239
GO:0048489 synaptic vesicle transport 42 7.201916
GO:0009952 anterior/posterior pattern formation 159 7.200232
GO:0019935 cyclic-nucleotide-mediated signaling 154 7.192229
GO:0008038 neuron recognition 26 7.141631
GO:0055082 cellular chemical homeostasis 468 7.106188
GO:0048592 eye morphogenesis 102 7.088702
GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 107 7.083893
GO:0048593 camera-type eye morphogenesis 73 7.07981
GO:0030705 cytoskeleton-dependent intracellular transport 35 7.068453
GO:0048732 gland development 211 7.067244
GO:0046928 regulation of neurotransmitter secretion 28 7.028545
GO:0060041 retina development in camera-type eye 76 7.01271
GO:0006511 ubiquitin-dependent protein catabolic process 317 7.010323
GO:0051130 positive regulation of cellular component organization 363 7.007345
GO:0010970 microtubule-based transport 31 6.999475
GO:0007416 synapse assembly 34 6.989973
GO:0007194 negative regulation of adenylate cyclase activity 55 6.985062
GO:0031280 negative regulation of cyclase activity 55 6.985062
GO:0051350 negative regulation of lyase activity 55 6.985062
GO:0050773 regulation of dendrite development 40 6.984845
GO:0043583 ear development 135 6.981605
GO:0016567 protein ubiquitination 321 6.969059
GO:0006521 regulation of cellular amino acid metabolic process 55 6.958952
GO:0032446 protein modification by small protein conjugation 342 6.955083
GO:0071375 cellular response to peptide hormone stimulus 237 6.928586
GO:0033238 regulation of cellular amine metabolic process 68 6.923712
GO:0001501 skeletal system development 317 6.918593
GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 140 6.913962
GO:0032228 regulation of synaptic transmission, GABAergic 24 6.902916
GO:0042063 gliogenesis 109 6.864604
GO:0007202 activation of phospholipase C activity 105 6.860158
GO:0048511 rhythmic process 179 6.849003
GO:0016337 cell-cell adhesion 296 6.837124
GO:0048839 inner ear development 112 6.793516
GO:0033555 multicellular organismal response to stress 41 6.785677
GO:0021766 hippocampus development 42 6.769964
GO:0010863 positive regulation of phospholipase C activity 106 6.767789
GO:0006397 mRNA processing 378 6.75888
GO:0010001 glial cell differentiation 95 6.711343
GO:0007507 heart development 295 6.709122
GO:0006873 cellular ion homeostasis 447 6.689528
GO:0030902 hindbrain development 89 6.67781
GO:0043269 regulation of ion transport 167 6.668157
GO:0019941 modification-dependent protein catabolic process 324 6.651675
GO:0006112 energy reserve metabolic process 141 6.648667
GO:0045665 negative regulation of neuron differentiation 49 6.641294
GO:0046578 regulation of Ras protein signal transduction 243 6.640735
GO:0021510 spinal cord development 62 6.573171
GO:0008306 associative learning 41 6.572994
GO:0072395 signal transduction involved in cell cycle checkpoint 64 6.493551
GO:0072404 signal transduction involved in G1/S transition checkpoint 64 6.493551
GO:0051129 negative regulation of cellular component organization 249 6.484678
GO:0043632 modification-dependent macromolecule catabolic process 327 6.471196
GO:0051899 membrane depolarization 44 6.450938
GO:0031345 negative regulation of cell projection organization 52 6.419687
GO:0007214 gamma-aminobutyric acid signaling pathway 19 6.419578
GO:0010518 positive regulation of phospholipase activity 111 6.415351
GO:0010959 regulation of metal ion transport 143 6.38739
GO:0050805 negative regulation of synaptic transmission 33 6.376527
GO:0035239 tube morphogenesis 209 6.372417
GO:0000165 MAPKKK cascade 226 6.338664
GO:0022029 telencephalon cell migration 33 6.337744
GO:0010517 regulation of phospholipase activity 117 6.308534
GO:0007264 small GTPase mediated signal transduction 393 6.301271
GO:0016079 synaptic vesicle exocytosis 23 6.292695
GO:0016055 Wnt receptor signaling pathway 150 6.279487
GO:0043434 response to peptide hormone stimulus 354 6.276812
GO:0051603 proteolysis involved in cellular protein catabolic process 334 6.257332
GO:0021885 forebrain cell migration 35 6.249071
GO:0006366 transcription from RNA polymerase II promoter 324 6.247702
GO:0040008 regulation of growth 441 6.238936
GO:0048736 appendage development 118 6.235421
GO:0060173 limb development 118 6.235421
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 63 6.229389
GO:0072401 signal transduction involved in DNA integrity checkpoint 63 6.229389
GO:0072413 signal transduction involved in mitotic cell cycle checkpoint 63 6.229389
GO:0072422 signal transduction involved in DNA damage checkpoint 63 6.229389
GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint 63 6.229389
GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint 63 6.229389
GO:0048705 skeletal system morphogenesis 139 6.210299
GO:0007613 memory 53 6.202199
GO:0034220 ion transmembrane transport 202 6.200203
GO:0048706 embryonic skeletal system development 88 6.177275
GO:0051970 negative regulation of transmission of nerve impulse 37 6.154214
GO:0007270 neuron-neuron synaptic transmission 35 6.149486
GO:0035107 appendage morphogenesis 111 6.14829
GO:0035108 limb morphogenesis 111 6.14829
GO:0060078 regulation of postsynaptic membrane potential 29 6.123282
GO:0044257 cellular protein catabolic process 340 6.114465
GO:0008380 RNA splicing 297 6.1111
GO:0050801 ion homeostasis 489 6.105685
GO:0032535 regulation of cellular component size 367 6.105316
GO:0070646 protein modification by small protein removal 66 6.09742
GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 60 6.079801
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 107 6.070724
GO:0050905 neuromuscular process 65 6.061595
GO:0090066 regulation of anatomical structure size 411 6.042366
GO:0048729 tissue morphogenesis 337 6.0319
GO:0030522 intracellular receptor mediated signaling pathway 115 6.008717
GO:0031290 retinal ganglion cell axon guidance 14 6.00246
GO:0000375 RNA splicing, via transesterification reactions 199 6.001684
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 193 6.001507
GO:0000398 nuclear mRNA splicing, via spliceosome 193 6.001507
GO:0051966 regulation of synaptic transmission, glutamatergic 24 5.989664
GO:0032868 response to insulin stimulus 233 5.985739
GO:0030111 regulation of Wnt receptor signaling pathway 141 5.947858
GO:0003007 heart morphogenesis 130 5.937401
GO:0019228 regulation of action potential in neuron 71 5.927297
GO:0045762 positive regulation of adenylate cyclase activity 62 5.923166
GO:0050808 synapse organization 61 5.913947
GO:0032412 regulation of ion transmembrane transporter activity 65 5.907703
GO:0030509 BMP signaling pathway 45 5.902535
GO:0042596 fear response 17 5.882618
GO:0043523 regulation of neuron apoptosis 133 5.8781
GO:0030516 regulation of axon extension 39 5.878044
GO:0050803 regulation of synapse structure and activity 38 5.876457
GO:0016579 protein deubiquitination 55 5.874618
GO:0007173 epidermal growth factor receptor signaling pathway 77 5.856792
GO:0032869 cellular response to insulin stimulus 181 5.853497
GO:0060193 positive regulation of lipase activity 119 5.843374
GO:0008088 axon cargo transport 14 5.839487
GO:0006184 GTP catabolic process 152 5.830264
GO:0045666 positive regulation of neuron differentiation 52 5.823855
GO:0031346 positive regulation of cell projection organization 105 5.8015
GO:0022898 regulation of transmembrane transporter activity 69 5.79625
GO:0031645 negative regulation of neurological system process 41 5.788695
GO:0071158 positive regulation of cell cycle arrest 70 5.771438
GO:0031281 positive regulation of cyclase activity 63 5.767112
GO:0006816 calcium ion transport 121 5.759522
GO:0007632 visual behavior 30 5.744525
GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling pathway 43 5.743056
GO:0060191 regulation of lipase activity 140 5.702756
GO:0021915 neural tube development 96 5.680213
GO:0001964 startle response 18 5.675274
GO:0007190 activation of adenylate cyclase activity 61 5.672159
GO:0008542 visual learning 26 5.671241
GO:0032409 regulation of transporter activity 78 5.6702
GO:0009205 purine ribonucleoside triphosphate metabolic process 301 5.657884
GO:0006470 protein dephosphorylation 130 5.64755
GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 70 5.645749
GO:0003006 developmental process involved in reproduction 363 5.635478
GO:0031329 regulation of cellular catabolic process 343 5.634983
GO:0034765 regulation of ion transmembrane transport 76 5.631485
GO:0002009 morphogenesis of an epithelium 248 5.616651
GO:0060541 respiratory system development 142 5.607511
GO:0060079 regulation of excitatory postsynaptic membrane potential 23 5.604076
GO:0009199 ribonucleoside triphosphate metabolic process 302 5.595628
GO:0009144 purine nucleoside triphosphate metabolic process 305 5.591247
GO:0002209 behavioral defense response 14 5.590906
GO:0007272 ensheathment of neurons 59 5.58746
GO:0008366 axon ensheathment 59 5.58746
GO:0050771 negative regulation of axonogenesis 31 5.581039
GO:0048024 regulation of nuclear mRNA splicing, via spliceosome 24 5.580584
GO:0021872 forebrain generation of neurons 27 5.569989
GO:0030330 DNA damage response, signal transduction by p53 class mediator 88 5.554363
GO:0042552 myelination 55 5.55189
GO:0021795 cerebral cortex cell migration 24 5.5207
GO:0016358 dendrite development 41 5.505555
GO:0008286 insulin receptor signaling pathway 138 5.501454
GO:0042176 regulation of protein catabolic process 120 5.497429
GO:0051924 regulation of calcium ion transport 121 5.494205
GO:0051349 positive regulation of lyase activity 65 5.486677
GO:0043524 negative regulation of neuron apoptosis 74 5.48028
GO:0048639 positive regulation of developmental growth 36 5.473308
GO:0006376 mRNA splice site selection 18 5.471466
GO:0016570 histone modification 203 5.467664
GO:0000381 regulation of alternative nuclear mRNA splicing, via spliceosome 15 5.465722
GO:0001763 morphogenesis of a branching structure 142 5.465081
GO:0030326 embryonic limb morphogenesis 96 5.462433
GO:0035113 embryonic appendage morphogenesis 96 5.462433
GO:0031646 positive regulation of neurological system process 41 5.460578
GO:0007616 long-term memory 15 5.442362
GO:0017157 regulation of exocytosis 59 5.429409
GO:0000209 protein polyubiquitination 156 5.42737
GO:0051247 positive regulation of protein metabolic process 429 5.423196
GO:0050806 positive regulation of synaptic transmission 35 5.422862
GO:0060562 epithelial tube morphogenesis 164 5.417227
GO:2000027 regulation of organ morphogenesis 94 5.392761
GO:0043254 regulation of protein complex assembly 146 5.389648
GO:0048814 regulation of dendrite morphogenesis 29 5.388186
GO:0009141 nucleoside triphosphate metabolic process 312 5.382279
GO:0016569 covalent chromatin modification 206 5.370332
GO:0050807 regulation of synapse organization 32 5.369483
GO:0031401 positive regulation of protein modification process 335 5.355454
GO:0072331 signal transduction by p53 class mediator 92 5.347979
GO:0014013 regulation of gliogenesis 48 5.346475
GO:0046039 GTP metabolic process 164 5.339671
GO:0030323 respiratory tube development 127 5.338862
GO:0030324 lung development 124 5.336851
GO:0016202 regulation of striated muscle tissue development 68 5.334001
GO:0007422 peripheral nervous system development 62 5.328353
GO:0072384 organelle transport along microtubule 17 5.327825
GO:0031333 negative regulation of protein complex assembly 55 5.320793
GO:0016311 dephosphorylation 145 5.320248
GO:0007600 sensory perception 441 5.312306
GO:0043484 regulation of RNA splicing 42 5.312304
GO:0050678 regulation of epithelial cell proliferation 156 5.288463
GO:0031098 stress-activated protein kinase signaling cascade 112 5.284094
GO:0048863 stem cell differentiation 60 5.282877
GO:0009880 embryonic pattern specification 49 5.278789
GO:0051147 regulation of muscle cell differentiation 74 5.275463
GO:0050772 positive regulation of axonogenesis 43 5.275344
GO:0051971 positive regulation of transmission of nerve impulse 38 5.27361
GO:0021781 glial cell fate commitment 14 5.265903
GO:0070838 divalent metal ion transport 150 5.26496
GO:0040012 regulation of locomotion 318 5.255842
GO:0008543 fibroblast growth factor receptor signaling pathway 78 5.235461
GO:0030278 regulation of ossification 114 5.230843
GO:0008361 regulation of cell size 286 5.225355
GO:0045667 regulation of osteoblast differentiation 70 5.223113
GO:0001662 behavioral fear response 13 5.219685
GO:0042471 ear morphogenesis 88 5.218736
GO:0048634 regulation of muscle organ development 70 5.21174
GO:0071779 G1/S transition checkpoint 80 5.20863
GO:0030177 positive regulation of Wnt receptor signaling pathway 54 5.206187
GO:0043087 regulation of GTPase activity 191 5.205466
GO:0021799 cerebral cortex radially oriented cell migration 12 5.199252
GO:0022037 metencephalon development 58 5.192778
GO:0060042 retina morphogenesis in camera-type eye 29 5.192028
GO:0035023 regulation of Rho protein signal transduction 139 5.176837
GO:0048663 neuron fate commitment 45 5.165358
GO:0035148 tube formation 79 5.141078
GO:0045778 positive regulation of ossification 36 5.130987
GO:0001838 embryonic epithelial tube formation 72 5.128935
GO:0042551 neuron maturation 21 5.127842
GO:0021700 developmental maturation 123 5.123797
GO:0033124 regulation of GTP catabolic process 193 5.117658
GO:0032270 positive regulation of cellular protein metabolic process 413 5.116716
GO:0021549 cerebellum development 53 5.116654
GO:0042472 inner ear morphogenesis 72 5.11417
GO:0060485 mesenchyme development 98 5.10912
GO:0031400 negative regulation of protein modification process 168 5.101505
GO:0051443 positive regulation of ubiquitin-protein ligase activity 79 5.095797
GO:0001841 neural tube formation 57 5.080488
GO:0051345 positive regulation of hydrolase activity 386 5.062997
GO:0030036 actin cytoskeleton organization 265 5.06072
GO:0051925 regulation of calcium ion transport via voltage-gated calcium channel activity 42 5.040138
GO:0001975 response to amphetamine 30 5.025539
GO:0090068 positive regulation of cell cycle process 122 5.022287
GO:0072175 epithelial tube formation 73 5.021641
GO:0072511 divalent inorganic cation transport 154 5.008961
GO:0007628 adult walking behavior 19 5.005723
GO:0046058 cAMP metabolic process 26 5.000368
GO:0006195 purine nucleotide catabolic process 253 4.975799
GO:0031575 mitotic cell cycle G1/S transition checkpoint 79 4.959751
GO:0051438 regulation of ubiquitin-protein ligase activity 93 4.959535
GO:0051963 regulation of synaptogenesis 24 4.95498
GO:0007218 neuropeptide signaling pathway 93 4.948667
GO:0019827 stem cell maintenance 45 4.948236
GO:0043547 positive regulation of GTPase activity 139 4.945758
GO:0040007 growth 269 4.945105
GO:0035235 ionotropic glutamate receptor signaling pathway 10 4.939805
GO:0048704 embryonic skeletal system morphogenesis 67 4.936914
GO:0060627 regulation of vesicle-mediated transport 150 4.934029
GO:0060828 regulation of canonical Wnt receptor signaling pathway 99 4.933675
GO:0001655 urogenital system development 169 4.930903
GO:0016331 morphogenesis of embryonic epithelium 90 4.927977
GO:0048488 synaptic vesicle endocytosis 16 4.921927
GO:0006163 purine nucleotide metabolic process 391 4.921358
GO:0003151 outflow tract morphogenesis 23 4.918388
GO:0000245 spliceosome assembly 39 4.916974
GO:0030879 mammary gland development 99 4.916714
GO:0048754 branching morphogenesis of a tube 113 4.91247
GO:0051493 regulation of cytoskeleton organization 196 4.900311
GO:0021879 forebrain neuron differentiation 18 4.895286
GO:0006913 nucleocytoplasmic transport 182 4.885791
GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter 96 4.881751
GO:0001649 osteoblast differentiation 56 4.875746
GO:0043086 negative regulation of catalytic activity 438 4.860558
GO:0021772 olfactory bulb development 24 4.847897
GO:0021988 olfactory lobe development 24 4.847897
GO:0048762 mesenchymal cell differentiation 84 4.845029
GO:0040013 negative regulation of locomotion 101 4.839596
GO:0021536 diencephalon development 55 4.829831
GO:0046887 positive regulation of hormone secretion 59 4.828559
GO:0007172 signal complex assembly 24 4.813431
GO:0007623 circadian rhythm 66 4.807937
GO:0051050 positive regulation of transport 352 4.803686
GO:0009203 ribonucleoside triphosphate catabolic process 225 4.794756
GO:0009207 purine ribonucleoside triphosphate catabolic process 225 4.794756
GO:0045685 regulation of glial cell differentiation 39 4.793314
GO:0014020 primary neural tube formation 47 4.793145
GO:0007548 sex differentiation 226 4.791005
GO:0051169 nuclear transport 184 4.786766
GO:0042770 signal transduction in response to DNA damage 111 4.784657
GO:2000602 regulation of interphase of mitotic cell cycle 121 4.77459
GO:0001558 regulation of cell growth 262 4.774169
GO:0032583 regulation of gene-specific transcription 97 4.769254
GO:0032940 secretion by cell 328 4.758115
GO:0007243 intracellular protein kinase cascade 398 4.754104
GO:0023014 signal transduction via phosphorylation event 398 4.754104
GO:0009146 purine nucleoside triphosphate catabolic process 226 4.723494
GO:0072523 purine-containing compound catabolic process 259 4.718913
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 46 4.703567
GO:0009261 ribonucleotide catabolic process 232 4.693221
GO:0009798 axis specification 72 4.691604
GO:0001843 neural tube closure 46 4.689819
GO:0009154 purine ribonucleotide catabolic process 230 4.687173
GO:0060070 canonical Wnt receptor signaling pathway 61 4.68039
GO:0021779 oligodendrocyte cell fate commitment 6 4.678264
GO:0009150 purine ribonucleotide metabolic process 327 4.672945
GO:0030308 negative regulation of cell growth 126 4.668082
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 72 4.662536
GO:0051351 positive regulation of ligase activity 83 4.645412
GO:0045792 negative regulation of cell size 133 4.640778
GO:0008285 negative regulation of cell proliferation 438 4.636261
GO:0051270 regulation of cellular component movement 311 4.633668
GO:0007631 feeding behavior 76 4.629655
GO:0009143 nucleoside triphosphate catabolic process 229 4.619531
GO:0051098 regulation of binding 124 4.601554
GO:0048608 reproductive structure development 212 4.575207
GO:0048048 embryonic eye morphogenesis 26 4.562323
GO:0051340 regulation of ligase activity 97 4.55457
GO:0043266 regulation of potassium ion transport 15 4.549722
GO:0043408 regulation of MAPKKK cascade 243 4.547862
GO:0030334 regulation of cell migration 283 4.535871
GO:0030811 regulation of nucleotide catabolic process 214 4.530399
GO:0033121 regulation of purine nucleotide catabolic process 214 4.530399
GO:0051494 negative regulation of cytoskeleton organization 70 4.512688
GO:0051248 negative regulation of protein metabolic process 263 4.507153
GO:0035137 hindlimb morphogenesis 33 4.479085
GO:0009166 nucleotide catabolic process 270 4.458114
GO:0031124 mRNA 3'-end processing 70 4.437496
GO:0014031 mesenchymal cell development 76 4.43553
GO:0044419 interspecies interaction between organisms 355 4.416646
GO:0007179 transforming growth factor beta receptor signaling pathway 64 4.380771
GO:0031398 positive regulation of protein ubiquitination 113 4.326919
GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process 295 4.201664
GO:0034656 nucleobase, nucleoside and nucleotide catabolic process 295 4.201664
GO:0030518 steroid hormone receptor signaling pathway 68 4.97057
GO:0018210 peptidyl-threonine modification 24 4.427036
GO:0003407 neural retina development 24 4.240703
GO:0048640 negative regulation of developmental growth 20 4.833681
GO:0032271 regulation of protein polymerization 89 4.498832
GO:0048813 dendrite morphogenesis 20 4.48728
GO:2000145 regulation of cell motility 289 4.317867
GO:0009187 cyclic nucleotide metabolic process 48 5.222993
GO:0033044 regulation of chromosome organization 69 4.310894
GO:0060384 innervation 7 4.742011
GO:0009259 ribonucleotide metabolic process 336 4.384305
GO:0030168 platelet activation 241 4.37455
GO:0021952 central nervous system projection neuron axonogenesis 10 4.598826
GO:0031397 negative regulation of protein ubiquitination 90 4.555653
GO:0060688 regulation of morphogenesis of a branching structure 41 4.4615
GO:0046903 secretion 447 4.337971
GO:0034332 adherens junction organization 38 4.747574
GO:0045669 positive regulation of osteoblast differentiation 38 4.632513
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 54 4.273501
GO:0021955 central nervous system neuron axonogenesis 13 4.684813
GO:0033674 positive regulation of kinase activity 325 4.244054
GO:0010738 regulation of protein kinase A signaling cascade 10 4.298749
GO:0051271 negative regulation of cellular component movement 93 4.043751
GO:0042490 mechanoreceptor differentiation 30 4.559045
GO:0021515 cell differentiation in spinal cord 34 4.485758
GO:0051967 negative regulation of synaptic transmission, glutamatergic 7 4.453555
GO:0050684 regulation of mRNA processing 34 4.401314
GO:0006403 RNA localization 129 4.377086
GO:0060021 palate development 57 4.566655
GO:0030163 protein catabolic process 366 5.460773
GO:0072521 purine-containing compound metabolic process 426 3.969586
GO:0021895 cerebral cortex neuron differentiation 17 4.394435
GO:0031113 regulation of microtubule polymerization 17 4.371789
GO:0014072 response to isoquinoline alkaloid 23 4.311973
GO:0043278 response to morphine 23 4.311973
GO:0030029 actin filament-based process 304 4.251544
GO:0006820 anion transport 146 4.020659
GO:0031396 regulation of protein ubiquitination 151 4.034147
GO:0032147 activation of protein kinase activity 148 4.514709
GO:0051051 negative regulation of transport 211 4.118182
GO:0008016 regulation of heart contraction 89 4.218298
GO:0001944 vasculature development 321 4.415614
GO:0033043 regulation of organelle organization 357 4.655585
GO:0021535 cell migration in hindbrain 6 4.362406
GO:0021778 oligodendrocyte cell fate specification 5 4.569822
GO:0021780 glial cell fate specification 5 4.569822
GO:0032956 regulation of actin cytoskeleton organization 131 4.380263
GO:0045860 positive regulation of protein kinase activity 312 3.99569
GO:0007212 dopamine receptor signaling pathway 17 4.277767
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 59 4.015183
GO:0009953 dorsal/ventral pattern formation 75 4.243291
GO:0051153 regulation of striated muscle cell differentiation 38 4.341661
GO:2000045 regulation of G1/S transition of mitotic cell cycle 87 4.50814
GO:0050885 neuromuscular process controlling balance 37 4.331062
GO:0046660 female sex differentiation 99 4.216348
GO:0009416 response to light stimulus 162 4.265363
GO:0034762 regulation of transmembrane transport 178 4.21544
GO:0048016 inositol phosphate-mediated signaling 61 4.214042
GO:0018107 peptidyl-threonine phosphorylation 21 4.738481
GO:0090102 cochlea development 21 4.504043
GO:0055123 digestive system development 92 3.998283
GO:0051058 negative regulation of small GTPase mediated signal transduction 27 4.410962
GO:0043271 negative regulation of ion transport 33 4.106498
GO:0010464 regulation of mesenchymal cell proliferation 33 4.095331
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 78 4.388211
GO:0007158 neuron cell-cell adhesion 11 5.091728
GO:0030517 negative regulation of axon extension 13 4.371722
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 119 4.328611
GO:0051347 positive regulation of transferase activity 334 4.002832
GO:0031056 regulation of histone modification 40 4.438936
GO:0002793 positive regulation of peptide secretion 40 4.416549
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 67 4.301444
GO:0072001 renal system development 134 4.10314
GO:0002053 positive regulation of mesenchymal cell proliferation 30 4.401723
GO:0001709 cell fate determination 40 4.981809
GO:0060603 mammary gland duct morphogenesis 24 4.051127
GO:0002089 lens morphogenesis in camera-type eye 19 4.2374
GO:0021675 nerve development 49 4.316448
GO:0060349 bone morphogenesis 48 4.172102
GO:0051352 negative regulation of ligase activity 72 4.474928
GO:0051444 negative regulation of ubiquitin-protein ligase activity 72 4.474928
GO:0048589 developmental growth 151 4.266881
GO:0043279 response to alkaloid 86 4.255113
GO:0060134 prepulse inhibition 13 4.220649
GO:0060081 membrane hyperpolarization 13 4.167448
GO:0022612 gland morphogenesis 81 4.057024
GO:0045995 regulation of embryonic development 57 4.032689
GO:0060548 negative regulation of cell death 500 3.946854
GO:0048565 digestive tract development 84 3.928327
GO:0001568 blood vessel development 295 3.89659
GO:0046777 protein autophosphorylation 94 4.7409
GO:0045859 regulation of protein kinase activity 485 4.060017
GO:0001708 cell fate specification 48 4.118442
GO:0048596 embryonic camera-type eye morphogenesis 21 4.266224
GO:0001657 ureteric bud development 77 4.163061
GO:0001701 in utero embryonic development 228 3.727918
GO:0014037 Schwann cell differentiation 15 4.32387
GO:0043576 regulation of respiratory gaseous exchange 15 4.31357
GO:0045927 positive regulation of growth 119 4.226386
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 83 4.184395
GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 10 4.042077
GO:0051403 stress-activated MAPK cascade 53 4.33247
GO:0032269 negative regulation of cellular protein metabolic process 252 4.001566
GO:0007413 axonal fasciculation 11 4.800079
GO:0021889 olfactory bulb interneuron differentiation 11 4.403871
GO:0042698 ovulation cycle 97 3.995696
GO:0051149 positive regulation of muscle cell differentiation 44 4.444219
GO:0016198 axon choice point recognition 7 4.294096
GO:0071377 cellular response to glucagon stimulus 36 4.127559
GO:0001822 kidney development 127 4.007318
GO:0006606 protein import into nucleus 80 3.960595
GO:0032272 negative regulation of protein polymerization 41 4.101891
GO:0050680 negative regulation of epithelial cell proliferation 65 4.005157
GO:0060736 prostate gland growth 11 4.066483
GO:0008406 gonad development 177 3.88228
GO:0032970 regulation of actin filament-based process 135 4.097583
GO:0050657 nucleic acid transport 124 4.047701
GO:0050658 RNA transport 124 4.047701
GO:0051236 establishment of RNA localization 124 4.047701
GO:0010828 positive regulation of glucose transport 28 4.237651
GO:0014048 regulation of glutamate secretion 16 4.449654
GO:0006688 glycosphingolipid biosynthetic process 14 4.025678
GO:0007618 mating 30 4.149403
GO:0060429 epithelium development 409 3.809931
GO:0030178 negative regulation of Wnt receptor signaling pathway 83 4.057245
GO:0009755 hormone-mediated signaling pathway 31 3.90469
GO:0043113 receptor clustering 16 4.368707
GO:0006369 termination of RNA polymerase II transcription 44 4.320301
GO:0060420 regulation of heart growth 19 4.069944
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 80 3.854494
GO:0010565 regulation of cellular ketone metabolic process 141 4.138313
GO:0032230 positive regulation of synaptic transmission, GABAergic 9 4.166272
GO:0006198 cAMP catabolic process 9 4.15397
GO:0016477 cell migration 456 4.29426
GO:0046326 positive regulation of glucose import 25 4.04394
GO:0046545 development of primary female sexual characteristics 94 3.951943
GO:0015698 inorganic anion transport 94 4.285909
GO:0046580 negative regulation of Ras protein signal transduction 26 4.068668
GO:0045773 positive regulation of axon extension 22 4.144685
GO:0031111 negative regulation of microtubule polymerization or depolymerization 23 4.021275
GO:0061180 mammary gland epithelium development 41 3.964199
GO:0060537 muscle tissue development 168 3.836158
GO:0060291 long-term synaptic potentiation 11 4.035118
GO:0051216 cartilage development 102 3.933507
GO:0001656 metanephros development 57 3.884683
GO:0061061 muscle structure development 306 3.817926
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 9 4.052492
GO:0048641 regulation of skeletal muscle tissue development 37 4.103018
GO:2000146 negative regulation of cell motility 88 3.869863
GO:0034504 protein localization to nucleus 103 3.904954
GO:0002088 lens development in camera-type eye 46 4.00174
GO:0021542 dentate gyrus development 8 4.280988
GO:0042058 regulation of epidermal growth factor receptor signaling pathway 59 3.808899
GO:0018105 peptidyl-serine phosphorylation 51 3.87494
GO:0006405 RNA export from nucleus 67 3.803379
GO:0045161 neuronal ion channel clustering 9 4.012045
GO:0019233 sensory perception of pain 39 4.199333
GO:0045216 cell-cell junction organization 100 3.961065
GO:0032229 negative regulation of synaptic transmission, GABAergic 8 4.187174
GO:0010632 regulation of epithelial cell migration 16 4.121083
GO:0051028 mRNA transport 111 3.812196
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity 269 3.681989
GO:0090046 regulation of transcription regulator activity 269 3.681989
GO:0051329 interphase of mitotic cell cycle 304 3.688012
GO:0090277 positive regulation of peptide hormone secretion 39 4.1509
GO:0071804 cellular potassium ion transport 39 4.150141
GO:0071805 potassium ion transmembrane transport 39 4.150141
GO:0031123 RNA 3'-end processing 83 3.938243
GO:0061351 neural precursor cell proliferation 35 4.249734
GO:0045137 development of primary sexual characteristics 198 4.197934
GO:0021696 cerebellar cortex morphogenesis 18 3.876936
GO:0022602 ovulation cycle process 88 3.750452
GO:0018209 peptidyl-serine modification 61 3.916179
GO:0045787 positive regulation of cell cycle 90 3.788635
GO:0006814 sodium ion transport 126 4.524119
GO:0021533 cell differentiation in hindbrain 16 4.05388
GO:2000177 regulation of neural precursor cell proliferation 31 3.75839
GO:0040019 positive regulation of embryonic development 7 3.974717
GO:0040014 regulation of multicellular organism growth 57 3.748867
GO:0045926 negative regulation of growth 158 3.932371
GO:0032844 regulation of homeostatic process 182 3.854537
GO:0060348 bone development 66 3.788009
GO:0010976 positive regulation of neuron projection development 37 3.995627
GO:0007018 microtubule-based movement 120 3.685747
GO:0046324 regulation of glucose import 35 3.954647
GO:0021575 hindbrain morphogenesis 29 3.86256
GO:0043267 negative regulation of potassium ion transport 6 4.08613
GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway 47 4.738636
GO:0010578 regulation of adenylate cyclase activity involved in G-protein signaling pathway 47 4.738636
GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway 47 4.738636
GO:0060606 tube closure 47 4.729175
GO:0048864 stem cell development 47 4.631318
GO:0055117 regulation of cardiac muscle contraction 14 3.820033
GO:0060113 inner ear receptor cell differentiation 28 3.756734
GO:0048742 regulation of skeletal muscle fiber development 27 3.88223
GO:0030336 negative regulation of cell migration 86 3.779982
GO:0051047 positive regulation of secretion 175 3.585298
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 6 4.079663
GO:0014706 striated muscle tissue development 155 3.706703
GO:0030238 male sex determination 9 3.9172
GO:0030521 androgen receptor signaling pathway 41 3.842002
GO:0001837 epithelial to mesenchymal transition 37 3.851723
GO:0048469 cell maturation 89 3.624083
GO:0060412 ventricular septum morphogenesis 14 3.781021
GO:0021697 cerebellar cortex formation 14 3.764649
GO:0060059 embryonic retina morphogenesis in camera-type eye 8 4.094017
GO:0010459 negative regulation of heart rate 5 4.055716
GO:0006821 chloride transport 61 3.711915
GO:0014014 negative regulation of gliogenesis 26 4.442185
GO:0035019 somatic stem cell maintenance 26 4.434688
GO:0032318 regulation of Ras GTPase activity 132 3.855234
GO:0000186 activation of MAPKK activity 43 3.95942
GO:0009743 response to carbohydrate stimulus 112 3.847748
GO:0050679 positive regulation of epithelial cell proliferation 91 4.049187
GO:0002062 chondrocyte differentiation 29 3.770127
GO:0060350 endochondral bone morphogenesis 27 3.825049
GO:0046700 heterocycle catabolic process 319 3.493184
GO:0051170 nuclear import 83 3.85465
GO:0006406 mRNA export from nucleus 60 3.694095
GO:0051952 regulation of amine transport 45 3.870131
GO:0051101 regulation of DNA binding 45 3.866808
GO:0010498 proteasomal protein catabolic process 160 3.577281
GO:0043066 negative regulation of apoptosis 480 3.441658
GO:0021587 cerebellum morphogenesis 25 3.780325
GO:0010675 regulation of cellular carbohydrate metabolic process 61 3.552566
GO:0003206 cardiac chamber morphogenesis 61 3.545705
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 159 3.589428
GO:0021782 glial cell development 55 3.675083
GO:0047496 vesicle transport along microtubule 9 3.83419
GO:0005513 detection of calcium ion 9 3.832593
GO:0007405 neuroblast proliferation 19 3.849254
GO:0042692 muscle cell differentiation 167 3.632903
GO:0022010 central nervous system myelination 11 3.76692
GO:0032291 axon ensheathment in central nervous system 11 3.76692
GO:0043069 negative regulation of programmed cell death 485 3.575082
GO:0061138 morphogenesis of a branching epithelium 121 4.445318
GO:0040034 regulation of development, heterochronic 8 3.930837
GO:0048505 regulation of timing of cell differentiation 8 3.930837
GO:0001963 synaptic transmission, dopaminergic 13 3.880331
GO:0050954 sensory perception of mechanical stimulus 105 3.795932
GO:0021522 spinal cord motor neuron differentiation 17 3.733289
GO:0042417 dopamine metabolic process 22 3.7301
GO:0030325 adrenal gland development 22 3.708825
GO:0006109 regulation of carbohydrate metabolic process 62 3.66059
GO:0045986 negative regulation of smooth muscle contraction 5 3.882198
GO:0045686 negative regulation of glial cell differentiation 20 3.890213
GO:0019098 reproductive behavior 19 3.595276
GO:0045822 negative regulation of heart contraction 12 3.741761
GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport 143 3.441109
GO:0061053 somite development 52 3.609964
GO:0031557 induction of programmed cell death in response to chemical stimulus 6 3.925397
GO:0055024 regulation of cardiac muscle tissue development 21 3.789128
GO:0008589 regulation of smoothened signaling pathway 38 3.653903
GO:0002076 osteoblast development 15 3.837868
GO:0033598 mammary gland epithelial cell proliferation 8 3.821351
GO:0043401 steroid hormone mediated signaling pathway 15 3.812799
GO:0031115 negative regulation of microtubule polymerization 7 3.751564
GO:0043112 receptor metabolic process 52 3.590131
GO:0002087 regulation of respiratory gaseous exchange by neurological system process 10 3.789205
GO:0035162 embryonic hemopoiesis 10 3.761592
GO:0032330 regulation of chondrocyte differentiation 28 3.668964
GO:0021695 cerebellar cortex development 28 3.54152
GO:0030155 regulation of cell adhesion 194 3.418058
GO:0040029 regulation of gene expression, epigenetic 115 3.491937
GO:0033762 response to glucagon stimulus 46 3.689794
GO:0051325 interphase 318 3.580017
GO:0048002 antigen processing and presentation of peptide antigen 90 3.669073
GO:0014073 response to tropane 23 3.661625
GO:0042220 response to cocaine 23 3.661625
GO:0017145 stem cell division 18 3.607842
GO:0021516 dorsal spinal cord development 18 3.595404
GO:0048514 blood vessel morphogenesis 245 3.529294
GO:0048268 clathrin coat assembly 6 3.790865
GO:0003205 cardiac chamber development 69 3.617015
GO:0051968 positive regulation of synaptic transmission, glutamatergic 9 3.750917
GO:0031076 embryonic camera-type eye development 29 3.530073
GO:0032320 positive regulation of Ras GTPase activity 84 3.494798
GO:0007617 mating behavior 15 3.726564
GO:0010717 regulation of epithelial to mesenchymal transition 30 3.697674
GO:0022011 myelination in peripheral nervous system 8 3.804197
GO:0032292 peripheral nervous system axon ensheathment 8 3.804197
GO:0034199 activation of protein kinase A activity 16 3.799934
GO:0060560 developmental growth involved in morphogenesis 53 3.558252
GO:0048709 oligodendrocyte differentiation 43 3.669887
GO:0033143 regulation of steroid hormone receptor signaling pathway 30 3.607631
GO:0071300 cellular response to retinoic acid 41 3.528349
GO:0061035 regulation of cartilage development 39 3.483278
GO:0051705 behavioral interaction between organisms 38 3.55776
GO:0042475 odontogenesis of dentine-containing tooth 44 3.555736
GO:0001756 somitogenesis 44 3.480619
GO:0043242 negative regulation of protein complex disassembly 42 3.365808
GO:0008037 cell recognition 64 3.413167
GO:0009214 cyclic nucleotide catabolic process 11 3.593105
GO:0044065 regulation of respiratory system process 11 3.589959
GO:0007210 serotonin receptor signaling pathway 13 3.676998
GO:0045815 positive regulation of gene expression, epigenetic 13 3.649878
GO:0014015 positive regulation of gliogenesis 26 3.465515
GO:0046834 lipid phosphorylation 17 3.557425
GO:0090278 negative regulation of peptide hormone secretion 25 3.549428
GO:0003208 cardiac ventricle morphogenesis 44 3.401035
GO:0021983 pituitary gland development 36 3.663512
GO:0009954 proximal/distal pattern formation 21 3.600431
GO:0048521 negative regulation of behavior 21 3.597074
GO:0071299 cellular response to vitamin A 42 3.347163
GO:0003231 cardiac ventricle development 58 3.315574
GO:0044270 cellular nitrogen compound catabolic process 321 3.245045
GO:0021891 olfactory bulb interneuron development 8 3.684512
GO:0060004 reflex 8 3.665359
GO:0021871 forebrain regionalization 17 3.514023
GO:0055021 regulation of cardiac muscle tissue growth 17 3.501608
GO:0017158 regulation of calcium ion-dependent exocytosis 22 3.417596
GO:0003281 ventricular septum development 24 3.618707
GO:0018394 peptidyl-lysine acetylation 78 3.582936
GO:0021892 cerebral cortex GABAergic interneuron differentiation 9 3.643291
GO:0048712 negative regulation of astrocyte differentiation 9 3.614342
GO:0045793 positive regulation of cell size 81 3.46527
GO:0007219 Notch signaling pathway 55 3.280366
GO:0051481 reduction of cytosolic calcium ion concentration 6 3.71364
GO:0040023 establishment of nucleus localization 10 3.650513
GO:0048096 chromatin-mediated maintenance of transcription 5 3.771299
GO:0048713 regulation of oligodendrocyte differentiation 19 3.317841
GO:0045767 regulation of anti-apoptosis 48 3.450136
GO:0016339 calcium-dependent cell-cell adhesion 24 3.410078
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 12 3.542594
GO:0051580 regulation of neurotransmitter uptake 9 3.542173
GO:0000082 G1/S transition of mitotic cell cycle 149 3.225092
GO:0046676 negative regulation of insulin secretion 23 3.492575
GO:0051168 nuclear export 84 3.25973
GO:0051100 negative regulation of binding 49 3.415507
GO:0035303 regulation of dephosphorylation 43 3.388606
GO:0061072 iris morphogenesis 6 3.667139
GO:0030815 negative regulation of cAMP metabolic process 9 3.476945
GO:0030818 negative regulation of cAMP biosynthetic process 9 3.476945
GO:0090009 primitive streak formation 9 3.408289
GO:0007530 sex determination 20 3.533623
GO:0060216 definitive hemopoiesis 8 3.641701
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 7 3.593501
GO:0032909 regulation of transforming growth factor-beta2 production 7 3.591332
GO:0045598 regulation of fat cell differentiation 47 3.360626
GO:0008283 cell proliferation 470 3.264464
GO:0007605 sensory perception of sound 97 3.385293
GO:0070936 protein K48-linked ubiquitination 32 4.539148
GO:0003279 cardiac septum development 31 3.355725
GO:0045637 regulation of myeloid cell differentiation 105 3.413383
GO:0060080 regulation of inhibitory postsynaptic membrane potential 9 3.299567
GO:0001942 hair follicle development 64 3.279187
GO:0022404 molting cycle process 64 3.279187
GO:0022405 hair cycle process 64 3.279187
GO:0033500 carbohydrate homeostasis 73 3.355443
GO:0042593 glucose homeostasis 73 3.355443
GO:0048009 insulin-like growth factor receptor signaling pathway 13 3.60475
GO:0044089 positive regulation of cellular component biogenesis 13 3.556794
GO:0030307 positive regulation of cell growth 76 3.343043
GO:0048665 neuron fate specification 22 3.310853
GO:0046879 hormone secretion 46 3.326075
GO:0050919 negative chemotaxis 10 3.505987
GO:0043392 negative regulation of DNA binding 22 3.298577
GO:0010676 positive regulation of cellular carbohydrate metabolic process 28 3.2741
GO:0045913 positive regulation of carbohydrate metabolic process 28 3.2741
GO:0045768 positive regulation of anti-apoptosis 39 3.074131
GO:0007254 JNK cascade 77 3.45111
GO:0018393 internal peptidyl-lysine acetylation 77 3.39308
GO:2000021 regulation of ion homeostasis 98 3.35336
GO:0010608 posttranscriptional regulation of gene expression 283 3.282424
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis 5 3.614707
GO:0035282 segmentation 69 3.388995
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 37 3.238206
GO:0060395 SMAD protein signal transduction 15 3.491398
GO:0060119 inner ear receptor cell development 15 3.433754
GO:0001704 formation of primary germ layer 60 3.296341
GO:0006475 internal protein amino acid acetylation 78 3.267415
GO:0009582 detection of abiotic stimulus 63 3.253736
GO:0045879 negative regulation of smoothened signaling pathway 16 3.487775
GO:0035249 synaptic transmission, glutamatergic 16 3.473334
GO:0048708 astrocyte differentiation 16 3.414615
GO:0009247 glycolipid biosynthetic process 16 3.337649
GO:0007519 skeletal muscle tissue development 80 3.152742
GO:0014065 phosphatidylinositol 3-kinase cascade 13 3.485038
GO:0001503 ossification 146 3.107126
GO:0002792 negative regulation of peptide secretion 26 3.302855
GO:0007213 muscarinic acetylcholine receptor signaling pathway 12 3.281536
GO:0032332 positive regulation of chondrocyte differentiation 14 3.370037
GO:0009950 dorsal/ventral axis specification 21 3.381755
GO:0090004 positive regulation of establishment of protein localization in plasma membrane 11 3.391175
GO:0045746 negative regulation of Notch signaling pathway 11 3.339305
GO:0003338 metanephros morphogenesis 16 3.304273
GO:0010634 positive regulation of epithelial cell migration 11 3.2925
GO:0071503 response to heparin 5 3.573665
GO:0003357 noradrenergic neuron differentiation 5 3.554076
GO:0006607 NLS-bearing substrate import into nucleus 13 3.419682
GO:0006473 protein acetylation 85 3.070137
GO:0046716 muscle cell homeostasis 14 3.304184
GO:0030520 estrogen receptor signaling pathway 16 3.256853
GO:0001661 conditioned taste aversion 5 3.443741
GO:0048566 embryonic digestive tract development 29 3.103112
GO:0003214 cardiac left ventricle morphogenesis 8 3.430147
GO:0003207 cardiac chamber formation 8 3.401591
GO:0003211 cardiac ventricle formation 8 3.401591
GO:0009914 hormone transport 50 3.069591
GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 55 3.030096
GO:0021692 cerebellar Purkinje cell layer morphogenesis 8 3.373596
GO:0021694 cerebellar Purkinje cell layer formation 8 3.373596
GO:0021702 cerebellar Purkinje cell differentiation 8 3.373596
GO:0060174 limb bud formation 8 3.347796
GO:0043623 cellular protein complex assembly 179 2.904021
GO:0035024 negative regulation of Rho protein signal transduction 8 3.260044
GO:0060993 kidney morphogenesis 27 3.180436
GO:0060425 lung morphogenesis 27 3.142645
GO:0045639 positive regulation of myeloid cell differentiation 47 3.033842
GO:0007599 hemostasis 495 3.060824
GO:0007265 Ras protein signal transduction 124 3.234281
GO:2000241 regulation of reproductive process 124 3.201139
GO:0009895 negative regulation of catabolic process 56 3.088131
GO:0010906 regulation of glucose metabolic process 52 3.254326
GO:0001504 neurotransmitter uptake 13 3.358518
GO:0016925 protein sumoylation 13 3.336492
GO:0034130 toll-like receptor 1 signaling pathway 69 3.257711
GO:0034134 toll-like receptor 2 signaling pathway 69 3.257711
GO:0030514 negative regulation of BMP signaling pathway 26 3.19379
GO:0007183 SMAD protein complex assembly 8 3.239123
GO:0007369 gastrulation 96 2.997433
GO:0034142 toll-like receptor 4 signaling pathway 76 2.951294
GO:0014044 Schwann cell development 10 3.439803
GO:0070588 calcium ion transmembrane transport 33 3.309071
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb 8 3.17287
GO:0070848 response to growth factor stimulus 88 3.255091
GO:0051962 positive regulation of nervous system development 12 3.178761
GO:0051965 positive regulation of synaptogenesis 12 3.178761
GO:0009948 anterior/posterior axis specification 34 2.975296
GO:0040018 positive regulation of multicellular organism growth 22 3.066603
GO:0042303 molting cycle 67 3.161168
GO:0042633 hair cycle 67 3.161168
GO:0043467 regulation of generation of precursor metabolites and energy 40 3.12411
GO:0060052 neurofilament cytoskeleton organization 6 3.376697
GO:0035278 negative regulation of translation involved in gene silencing by miRNA 6 3.373039
GO:0040033 negative regulation of translation, ncRNA-mediated 6 3.373039
GO:0045974 regulation of translation, ncRNA-mediated 6 3.373039
GO:0010719 negative regulation of epithelial to mesenchymal transition 9 3.088197
GO:0014033 neural crest cell differentiation 49 2.872453
GO:0034330 cell junction organization 155 3.125807
GO:0021801 cerebral cortex radial glia guided migration 6 3.33381
GO:0048546 digestive tract morphogenesis 41 3.185618
GO:0001892 embryonic placenta development 53 3.239838
GO:0051961 negative regulation of nervous system development 5 3.42948
GO:0048934 peripheral nervous system neuron differentiation 10 3.378798
GO:0048935 peripheral nervous system neuron development 10 3.378798
GO:0071108 protein K48-linked deubiquitination 10 3.320346
GO:0035116 embryonic hindlimb morphogenesis 25 3.090806
GO:0060998 regulation of dendritic spine development 9 3.058315
GO:0016572 histone phosphorylation 9 3.017885
GO:0060538 skeletal muscle organ development 86 2.963124
GO:0006582 melanin metabolic process 9 2.961161
GO:0042438 melanin biosynthetic process 9 2.961161
GO:0060896 neural plate pattern specification 9 2.951412
GO:0043525 positive regulation of neuron apoptosis 33 2.98094
GO:0043268 positive regulation of potassium ion transport 6 3.298023
GO:0048265 response to pain 18 3.025715
GO:0010977 negative regulation of neuron projection development 23 3.218237
GO:0000956 nuclear-transcribed mRNA catabolic process 81 2.989978
GO:0030854 positive regulation of granulocyte differentiation 5 3.273818
GO:0043255 regulation of carbohydrate biosynthetic process 37 3.037091
GO:0071559 response to transforming growth factor beta stimulus 22 3.021977
GO:0034284 response to monosaccharide stimulus 94 3.011696
GO:0060068 vagina development 5 3.247818
GO:0031558 induction of apoptosis in response to chemical stimulus 5 3.217217
GO:0045931 positive regulation of mitotic cell cycle 27 3.025697
GO:0018205 peptidyl-lysine modification 99 3.103155
GO:0007596 blood coagulation 491 3.037633
GO:0050817 coagulation 491 3.037633
GO:0001958 endochondral ossification 16 3.160513
GO:0007026 negative regulation of microtubule depolymerization 16 3.154712
GO:0008593 regulation of Notch signaling pathway 20 3.097679
GO:0021517 ventral spinal cord development 20 3.095202
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 72 3.268721
GO:0010639 negative regulation of organelle organization 136 2.983559
GO:0060992 response to fungicide 9 2.935974
GO:0014059 regulation of dopamine secretion 17 3.222716
GO:0006402 mRNA catabolic process 92 2.955028
GO:0034138 toll-like receptor 3 signaling pathway 63 3.080891
GO:0030837 negative regulation of actin filament polymerization 34 2.802152
GO:0010522 regulation of calcium ion transport into cytosol 37 3.02643
GO:0048483 autonomic nervous system development 37 2.97611
GO:0051279 regulation of release of sequestered calcium ion into cytosol 22 2.899777
GO:0032024 positive regulation of insulin secretion 32 3.292059
GO:0070997 neuron death 20 3.044278
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 40 5.070712
GO:0050974 detection of mechanical stimulus involved in sensory perception 10 3.241797
GO:0046854 phosphatidylinositol phosphorylation 16 3.10768
GO:0071901 negative regulation of protein serine/threonine kinase activity 77 3.105548
GO:0007274 neuromuscular synaptic transmission 16 3.092951
GO:0048670 regulation of collateral sprouting 7 3.343047
GO:0016188 synaptic vesicle maturation 7 3.336742
GO:0071295 cellular response to vitamin 51 2.755921
GO:0000077 DNA damage checkpoint 119 3.014081
GO:0009746 response to hexose stimulus 92 2.836875
GO:0030800 negative regulation of cyclic nucleotide metabolic process 10 3.15139
GO:0030803 negative regulation of cyclic nucleotide biosynthetic process 10 3.15139
GO:0030809 negative regulation of nucleotide biosynthetic process 10 3.15139
GO:0048841 regulation of axon extension involved in axon guidance 10 3.112525
GO:0048715 negative regulation of oligodendrocyte differentiation 10 3.071951
GO:0015711 organic anion transport 62 2.832172
GO:0003085 negative regulation of systemic arterial blood pressure 9 2.893891
GO:0010469 regulation of receptor activity 42 2.885781
GO:0050686 negative regulation of mRNA processing 9 2.885312
GO:0031110 regulation of microtubule polymerization or depolymerization 35 3.148859
GO:0045786 negative regulation of cell cycle 217 2.911875
GO:0010594 regulation of endothelial cell migration 51 2.714611
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 10 3.018542
GO:0048332 mesoderm morphogenesis 49 2.785928
GO:0048103 somatic stem cell division 15 3.341667
GO:0031128 developmental induction 27 2.986748
GO:0046888 negative regulation of hormone secretion 41 2.965122
GO:0009896 positive regulation of catabolic process 99 2.932335
GO:0090192 regulation of glomerulus development 10 2.997536
GO:0008584 male gonad development 86 2.800791
GO:0030035 microspike assembly 27 2.949488
GO:0031058 positive regulation of histone modification 27 2.943097
GO:0045599 negative regulation of fat cell differentiation 25 2.977452
GO:0080135 regulation of cellular response to stress 181 2.898794
GO:0048710 regulation of astrocyte differentiation 15 3.267751
GO:0033120 positive regulation of RNA splicing 5 3.18462
GO:0021545 cranial nerve development 35 3.091866
GO:0043543 protein acylation 97 3.026267
GO:0021873 forebrain neuroblast division 8 2.967308
GO:0055057 neuroblast division 8 2.967308
GO:0048172 regulation of short-term neuronal synaptic plasticity 8 2.945094
GO:0008045 motor axon guidance 15 3.185732
GO:0032102 negative regulation of response to external stimulus 88 3.006037
GO:0051480 cytosolic calcium ion homeostasis 136 2.879515
GO:0045776 negative regulation of blood pressure 31 2.994037
GO:0060065 uterus development 10 2.948871
GO:0010627 regulation of intracellular protein kinase cascade 444 2.734161
GO:0060411 cardiac septum morphogenesis 21 3.014753
GO:0016573 histone acetylation 75 3.175324
GO:0021544 subpallium development 15 3.099773
GO:0051592 response to calcium ion 77 2.99496
GO:0045168 cell-cell signaling involved in cell fate commitment 28 2.984265
GO:0042752 regulation of circadian rhythm 32 2.968688
GO:0060322 head development 30 3.006965
GO:0009190 cyclic nucleotide biosynthetic process 30 2.982189
GO:0033673 negative regulation of kinase activity 132 2.960067
GO:0046661 male sex differentiation 106 2.867776
GO:0060043 regulation of cardiac muscle cell proliferation 15 3.034114
GO:0030510 regulation of BMP signaling pathway 50 2.846454
GO:0050922 negative regulation of chemotaxis 14 3.054398
GO:0051647 nucleus localization 14 3.03356
GO:0000578 embryonic axis specification 26 2.976556
GO:0010827 regulation of glucose transport 70 2.808668
GO:0060324 face development 25 2.847042
GO:0050999 regulation of nitric-oxide synthase activity 30 2.917784
GO:0045732 positive regulation of protein catabolic process 64 3.079686
GO:0061039 ovum-producing ovary development 72 2.941252
GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 22 2.829547
GO:0060402 calcium ion transport into cytosol 29 2.826094
GO:0007601 visual perception 201 2.786429
GO:0007276 gamete generation 452 2.94262
GO:0030850 prostate gland development 34 2.747292
GO:0043967 histone H4 acetylation 31 2.870792
GO:0070302 regulation of stress-activated protein kinase signaling cascade 113 2.963925
GO:0043062 extracellular structure organization 179 2.7328
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 8 2.918006
GO:0001829 trophectodermal cell differentiation 15 2.997361
GO:0021903 rostrocaudal neural tube patterning 12 2.993473
GO:0006171 cAMP biosynthetic process 15 2.958555
GO:0030804 positive regulation of cyclic nucleotide biosynthetic process 34 2.594772
GO:0030810 positive regulation of nucleotide biosynthetic process 34 2.594772
GO:0021884 forebrain neuron development 8 2.872343
GO:0070371 ERK1 and ERK2 cascade 15 2.802972
GO:0031060 regulation of histone methylation 12 2.947915
GO:0072132 mesenchyme morphogenesis 7 3.15635
GO:0010842 retina layer formation 7 3.155411
GO:0060687 regulation of branching involved in prostate gland morphogenesis 7 3.154033
GO:0021877 forebrain neuron fate commitment 7 3.132584
GO:0043116 negative regulation of vascular permeability 7 3.058653
GO:0017156 calcium ion-dependent exocytosis 26 2.870904
GO:0001754 eye photoreceptor cell differentiation 32 2.8966
GO:0032925 regulation of activin receptor signaling pathway 13 3.115285
GO:0035020 regulation of Rac protein signal transduction 13 3.080044
GO:0060443 mammary gland morphogenesis 38 2.782181
GO:0043409 negative regulation of MAPKKK cascade 66 2.848066
GO:0050433 regulation of catecholamine secretion 32 2.892124
GO:0001952 regulation of cell-matrix adhesion 36 2.801623
GO:0046530 photoreceptor cell differentiation 33 2.814978
GO:0072298 regulation of metanephric glomerulus development 6 3.22663
GO:0008089 anterograde axon cargo transport 6 3.193061
GO:0045920 negative regulation of exocytosis 11 2.754288
GO:0008585 female gonad development 83 3.112658
GO:0060740 prostate gland epithelium morphogenesis 21 2.98233
GO:0001678 cellular glucose homeostasis 21 2.964007
GO:0061008 hepaticobiliary system development 74 2.879012
GO:0031114 regulation of microtubule depolymerization 17 2.878382
GO:0090003 regulation of establishment of protein localization in plasma membrane 17 2.850601
GO:0050775 positive regulation of dendrite morphogenesis 12 2.842498
GO:0060444 branching involved in mammary gland duct morphogenesis 17 2.834701
GO:0051348 negative regulation of transferase activity 140 2.639505
GO:0007163 establishment or maintenance of cell polarity 73 3.12594
GO:0007283 spermatogenesis 355 2.579487
GO:0048232 male gamete generation 355 2.579487
GO:0007386 compartment pattern formation 5 3.010243
GO:0046856 phosphatidylinositol dephosphorylation 7 2.993577
GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway 7 2.993043
GO:0042491 auditory receptor cell differentiation 16 2.98356
GO:0060526 prostate glandular acinus morphogenesis 7 2.982901
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 7 2.982901
GO:0015800 acidic amino acid transport 16 2.941125
GO:0003401 axis elongation 16 2.860957
GO:0032881 regulation of polysaccharide metabolic process 22 2.773272
GO:0070873 regulation of glycogen metabolic process 22 2.773272
GO:0035265 organ growth 25 2.719922
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 24 2.95136
GO:0030832 regulation of actin filament length 83 2.85765
GO:0032526 response to retinoic acid 83 2.853317
GO:0050953 sensory perception of light stimulus 202 2.84478
GO:0008624 induction of apoptosis by extracellular signals 119 2.779105
GO:0060850 regulation of transcription involved in cell fate commitment 10 2.828651
GO:0000188 inactivation of MAPK activity 24 2.800725
GO:0030833 regulation of actin filament polymerization 71 2.718267
GO:0051926 negative regulation of calcium ion transport 17 2.758146
GO:0010810 regulation of cell-substrate adhesion 72 2.879314
GO:0061136 regulation of proteasomal protein catabolic process 52 2.832437
GO:0046328 regulation of JNK cascade 104 2.848054
GO:0060525 prostate glandular acinus development 11 2.74637
GO:0001578 microtubule bundle formation 21 2.91033
GO:0002027 regulation of heart rate 29 2.67245
GO:0021756 striatum development 12 2.796166
GO:0043092 L-amino acid import 8 2.769371
GO:0060122 inner ear receptor stereocilium organization 8 2.758705
GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway 8 2.755997
GO:0046546 development of primary male sexual characteristics 100 2.695003
GO:0001702 gastrulation with mouth forming second 25 2.630808
GO:0003310 pancreatic A cell differentiation 5 2.942553
GO:0016199 axon midline choice point recognition 5 2.88581
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 13 2.781941
GO:0035136 forelimb morphogenesis 31 2.654629
GO:0060487 lung epithelial cell differentiation 13 2.711234
GO:0035264 multicellular organism growth 32 2.710847
GO:0045661 regulation of myoblast differentiation 16 2.836591
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 44 2.758174
GO:0048745 smooth muscle tissue development 17 2.649645
GO:0046627 negative regulation of insulin receptor signaling pathway 17 2.649461
GO:0071326 cellular response to monosaccharide stimulus 17 2.629857
GO:0071331 cellular response to hexose stimulus 17 2.629857
GO:0071333 cellular response to glucose stimulus 17 2.629857
GO:0030901 midbrain development 28 2.853692
GO:0070169 positive regulation of biomineral tissue development 28 2.825003
GO:0006469 negative regulation of protein kinase activity 125 2.932118
GO:0021846 cell proliferation in forebrain 17 2.518534
GO:0043393 regulation of protein binding 67 2.733699
GO:0014070 response to organic cyclic compound 216 2.572838
GO:0051048 negative regulation of secretion 99 2.570028
GO:0007162 negative regulation of cell adhesion 58 2.618898
GO:0043407 negative regulation of MAP kinase activity 57 2.646567
GO:0006874 cellular calcium ion homeostasis 194 2.506035
GO:0034329 cell junction assembly 136 2.606562
GO:0045981 positive regulation of nucleotide metabolic process 37 2.527729
GO:0002756 MyD88-independent toll-like receptor signaling pathway 65 2.846421
GO:0046113 nucleobase catabolic process 9 2.764804
GO:0048679 regulation of axon regeneration 9 2.764224
GO:0070570 regulation of neuron projection regeneration 9 2.764224
GO:0051589 negative regulation of neurotransmitter transport 6 3.121591
GO:0048339 paraxial mesoderm development 12 2.767814
GO:0048015 phosphatidylinositol-mediated signaling 84 2.524396
GO:0048017 inositol lipid-mediated signaling 84 2.524396
GO:0035065 regulation of histone acetylation 19 2.90512
GO:0060749 mammary gland alveolus development 11 2.710751
GO:0061377 mammary gland lobule development 11 2.710751
GO:0033189 response to vitamin A 97 2.707213
GO:0007346 regulation of mitotic cell cycle 267 2.550386
GO:0042428 serotonin metabolic process 9 2.694003
GO:0051602 response to electrical stimulus 26 2.733432
GO:0001707 mesoderm formation 46 2.695796
GO:0035272 exocrine system development 37 2.354466
GO:0048538 thymus development 25 2.627727
GO:0043244 regulation of protein complex disassembly 58 2.500544
GO:0090090 negative regulation of canonical Wnt receptor signaling pathway 57 2.551934
GO:0021800 cerebral cortex tangential migration 6 2.991958
GO:0002052 positive regulation of neuroblast proliferation 11 2.634878
GO:0045687 positive regulation of glial cell differentiation 21 2.822185
GO:0034063 stress granule assembly 5 2.754892
GO:0014009 glial cell proliferation 5 2.6818
GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly 5 2.655908
GO:0060441 epithelial tube branching involved in lung morphogenesis 16 2.631179
GO:0015872 dopamine transport 5 2.620023
GO:0009125 nucleoside monophosphate catabolic process 16 2.618408
GO:0032413 negative regulation of ion transmembrane transporter activity 16 2.615988
GO:0060231 mesenchymal to epithelial transition 11 2.598704
GO:0009749 response to glucose stimulus 86 2.479682
GO:0008298 intracellular mRNA localization 5 2.614125
GO:0006887 exocytosis 198 2.572466
GO:0019079 viral genome replication 16 2.574267
GO:0006482 protein demethylation 16 2.545193
GO:0008214 protein dealkylation 16 2.545193
GO:0003382 epithelial cell morphogenesis 22 2.667142
GO:0007093 mitotic cell cycle checkpoint 125 2.576638
GO:0071634 regulation of transforming growth factor-beta production 16 2.464493
GO:0060045 positive regulation of cardiac muscle cell proliferation 10 2.745217
GO:0006208 pyrimidine base catabolic process 8 2.709381
GO:0072006 nephron development 40 2.664986
GO:0035051 cardiac cell differentiation 54 2.71375
GO:0043470 regulation of carbohydrate catabolic process 23 2.708378
GO:0043471 regulation of cellular carbohydrate catabolic process 23 2.708378
GO:0060512 prostate gland morphogenesis 23 2.695268
GO:0007050 cell cycle arrest 125 2.549727
GO:0046068 cGMP metabolic process 21 2.788615
GO:0015701 bicarbonate transport 14 2.775782
GO:0048041 focal adhesion assembly 14 2.768988
GO:0048070 regulation of developmental pigmentation 9 2.656452
GO:0051930 regulation of sensory perception of pain 18 2.761419
GO:0051931 regulation of sensory perception 18 2.761419
GO:0051893 regulation of focal adhesion assembly 13 2.648371
GO:0090109 regulation of cell-substrate junction assembly 13 2.648371
GO:0031112 positive regulation of microtubule polymerization or depolymerization 13 2.637482
GO:0043410 positive regulation of MAPKKK cascade 127 2.635108
GO:0048557 embryonic digestive tract morphogenesis 15 2.537528
GO:0032386 regulation of intracellular transport 135 2.497591
GO:0010907 positive regulation of glucose metabolic process 23 2.614593
GO:0008154 actin polymerization or depolymerization 22 2.647857
GO:0002755 MyD88-dependent toll-like receptor signaling pathway 73 2.984118
GO:0018958 phenol-containing compound metabolic process 54 2.636944
GO:0010563 negative regulation of phosphorus metabolic process 78 2.619759
GO:0045936 negative regulation of phosphate metabolic process 78 2.619759
GO:0045668 negative regulation of osteoblast differentiation 25 2.441027
GO:0045648 positive regulation of erythrocyte differentiation 15 2.466488
GO:0043405 regulation of MAP kinase activity 205 2.576005
GO:0051894 positive regulation of focal adhesion assembly 7 2.738467
GO:0032922 circadian regulation of gene expression 8 2.684641
GO:0060123 regulation of growth hormone secretion 8 2.684192
GO:0055012 ventricular cardiac muscle cell differentiation 16 2.407062
GO:0015807 L-amino acid transport 16 2.404372
GO:0050673 epithelial cell proliferation 34 2.334435
GO:0035067 negative regulation of histone acetylation 5 2.577206
GO:0071425 hemopoietic stem cell proliferation 9 2.560079
GO:0021794 thalamus development 10 2.672008
GO:0045749 negative regulation of S phase of mitotic cell cycle 10 2.650384
GO:0045862 positive regulation of proteolysis 58 2.472594
GO:0001659 temperature homeostasis 19 2.659965
GO:0045725 positive regulation of glycogen biosynthetic process 13 2.520019
GO:0005979 regulation of glycogen biosynthetic process 21 2.728966
GO:0010962 regulation of glucan biosynthetic process 21 2.728966
GO:0032885 regulation of polysaccharide biosynthetic process 21 2.728966
GO:0008105 asymmetric protein localization 12 2.645853
GO:0010562 positive regulation of phosphorus metabolic process 221 2.653645
GO:0045937 positive regulation of phosphate metabolic process 221 2.653645
GO:0048010 vascular endothelial growth factor receptor signaling pathway 21 2.622454
GO:0007517 muscle organ development 201 2.462935
GO:0060900 embryonic camera-type eye formation 10 2.626266
GO:0007017 microtubule-based process 285 2.555604
GO:0048843 negative regulation of axon extension involved in axon guidance 7 2.709227
GO:0060136 embryonic process involved in female pregnancy 7 2.706073
GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback 7 2.692158
GO:0060117 auditory receptor cell development 7 2.68435
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 30 2.68405
GO:0007216 metabotropic glutamate receptor signaling pathway 7 2.672884
GO:0032880 regulation of protein localization 252 2.610492
GO:0002093 auditory receptor cell morphogenesis 5 2.575716
GO:0043984 histone H4-K16 acetylation 5 2.564937
GO:0061088 regulation of sequestering of zinc ion 5 2.562326
GO:0007498 mesoderm development 88 2.476814
GO:0071277 cellular response to calcium ion 15 2.441328
GO:0015813 L-glutamate transport 15 2.424902
GO:0030858 positive regulation of epithelial cell differentiation 15 2.405227
GO:0071383 cellular response to steroid hormone stimulus 45 2.402127
GO:0048384 retinoic acid receptor signaling pathway 15 2.40122
GO:0051402 neuron apoptosis 15 2.391071
GO:0010243 response to organic nitrogen 118 2.488736
GO:0010741 negative regulation of intracellular protein kinase cascade 90 2.555148
GO:0071322 cellular response to carbohydrate stimulus 20 2.63862
GO:0060711 labyrinthine layer development 28 2.512432
GO:0031670 cellular response to nutrient 58 2.395465
GO:0002761 regulation of myeloid leukocyte differentiation 58 2.370061
GO:0048738 cardiac muscle tissue development 80 2.444419
GO:0009713 catechol biosynthetic process 15 2.354487
GO:0034312 diol biosynthetic process 15 2.354487
GO:0042423 catecholamine biosynthetic process 15 2.354487
GO:0031116 positive regulation of microtubule polymerization 10 2.561332
GO:0042476 odontogenesis 71 2.553113
GO:0002011 morphogenesis of an epithelial sheet 10 2.549641
GO:0032026 response to magnesium ion 10 2.498668
GO:2000179 positive regulation of neural precursor cell proliferation 19 2.431653
GO:0003156 regulation of organ formation 25 2.419622
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 16 2.354231
GO:0046885 regulation of hormone biosynthetic process 16 2.313013
GO:0006110 regulation of glycolysis 16 2.312314
GO:0021527 spinal cord association neuron differentiation 11 2.532266
GO:0003254 regulation of membrane depolarization 11 2.531476
GO:0032095 regulation of response to food 11 2.523724
GO:0009314 response to radiation 265 2.388441
GO:0001934 positive regulation of protein phosphorylation 194 2.351976
GO:0046034 ATP metabolic process 137 2.54423
GO:0048806 genitalia development 32 2.456366
GO:0006338 chromatin remodeling 89 2.649084
GO:0060602 branch elongation of an epithelium 11 2.494741
GO:0060571 morphogenesis of an epithelial fold 11 2.483068
GO:0048194 Golgi vesicle budding 11 2.480148
GO:2000178 negative regulation of neural precursor cell proliferation 11 2.432041
GO:0032410 negative regulation of transporter activity 22 2.432367
GO:0072273 metanephric nephron morphogenesis 12 2.530746
GO:0070076 histone lysine demethylation 13 2.378284
GO:0014075 response to amine stimulus 83 2.6742
GO:0030501 positive regulation of bone mineralization 26 2.6518
GO:0006900 membrane budding 26 2.62977
GO:0060788 ectodermal placode formation 14 2.615513
GO:0071696 ectodermal placode development 14 2.615513
GO:0071697 ectodermal placode morphogenesis 14 2.615513
GO:0046847 filopodium assembly 26 2.593732
GO:0070875 positive regulation of glycogen metabolic process 14 2.562546
GO:0060479 lung cell differentiation 14 2.544269
GO:0042462 eye photoreceptor cell development 26 2.518328
GO:0061036 positive regulation of cartilage development 10 2.445602
GO:0007492 endoderm development 42 2.403376
GO:0030816 positive regulation of cAMP metabolic process 29 2.452095
GO:0030819 positive regulation of cAMP biosynthetic process 29 2.452095
GO:0008063 Toll signaling pathway 77 2.540859
GO:0060401 cytosolic calcium ion transport 30 2.613907
GO:0042177 negative regulation of protein catabolic process 30 2.610065
GO:0015682 ferric iron transport 30 2.573271
GO:0033572 transferrin transport 30 2.573271
GO:0031069 hair follicle morphogenesis 24 2.521206
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 24 2.484185
GO:0030801 positive regulation of cyclic nucleotide metabolic process 36 2.556652
GO:0006754 ATP biosynthetic process 71 2.40602
GO:0000086 G2/M transition of mitotic cell cycle 116 2.357779
GO:0030100 regulation of endocytosis 89 2.601571
GO:0043090 amino acid import 9 2.528003
GO:0051642 centrosome localization 9 2.52488
GO:0033146 regulation of estrogen receptor signaling pathway 9 2.485791
GO:0051057 positive regulation of small GTPase mediated signal transduction 26 2.478183
GO:0045176 apical protein localization 9 2.472444
GO:0006886 intracellular protein transport 390 2.187792
GO:0003073 regulation of systemic arterial blood pressure 46 2.515182
GO:0071248 cellular response to metal ion 46 2.475039
GO:0001890 placenta development 88 2.333109
GO:0045663 positive regulation of myoblast differentiation 8 2.504926
GO:0043367 CD4-positive, alpha-beta T cell differentiation 8 2.49877
GO:0014049 positive regulation of glutamate secretion 8 2.47525
GO:0055074 calcium ion homeostasis 201 2.273946
GO:0006417 regulation of translation 168 2.312076
GO:0046825 regulation of protein export from nucleus 13 2.299816
GO:0007281 germ cell development 116 2.215239
GO:0001954 positive regulation of cell-matrix adhesion 17 2.363937
GO:0051291 protein heterooligomerization 50 2.293745
GO:0045844 positive regulation of striated muscle tissue development 12 2.470114
GO:0048636 positive regulation of muscle organ development 12 2.470114
GO:0050982 detection of mechanical stimulus 12 2.455263
GO:0021602 cranial nerve morphogenesis 12 2.433834
GO:0010718 positive regulation of epithelial to mesenchymal transition 20 2.275713
GO:0072189 ureter development 7 2.640778
GO:0001825 blastocyst formation 23 2.360064
GO:0031570 DNA integrity checkpoint 126 2.52109
GO:0008064 regulation of actin polymerization or depolymerization 81 2.563168
GO:0032350 regulation of hormone metabolic process 21 2.547415
GO:0032319 regulation of Rho GTPase activity 69 2.539878
GO:0042461 photoreceptor cell development 27 2.429909
GO:0010921 regulation of phosphatase activity 27 2.400001
GO:0032321 positive regulation of Rho GTPase activity 55 2.217939
GO:0045838 positive regulation of membrane potential 6 2.829971
GO:0021826 substrate-independent telencephalic tangential migration 6 2.807189
GO:0021843 substrate-independent telencephalic tangential interneuron migration 6 2.807189
GO:0030032 lamellipodium assembly 18 2.392479
GO:0070507 regulation of microtubule cytoskeleton organization 56 2.28061
GO:0009791 post-embryonic development 75 2.38691
GO:0009855 determination of bilateral symmetry 67 2.371827
GO:0051489 regulation of filopodium assembly 16 2.266368
GO:0007015 actin filament organization 90 2.30074
GO:0032098 regulation of appetite 11 2.384044
GO:0042327 positive regulation of phosphorylation 213 2.476633
GO:0048701 embryonic cranial skeleton morphogenesis 30 2.451983
GO:0006687 glycosphingolipid metabolic process 30 2.448337
GO:0016577 histone demethylation 15 2.206016
GO:0016578 histone deubiquitination 15 2.198481
GO:0035335 peptidyl-tyrosine dephosphorylation 58 2.332557
GO:0010817 regulation of hormone levels 192 2.267905
GO:0006584 catecholamine metabolic process 38 2.473651
GO:0031057 negative regulation of histone modification 14 2.50336
GO:0021854 hypothalamus development 14 2.461981
GO:0007435 salivary gland morphogenesis 26 2.431293
GO:0045921 positive regulation of exocytosis 20 2.175336
GO:0035195 gene silencing by miRNA 23 2.281903
GO:0046620 regulation of organ growth 40 2.469975
GO:0035305 negative regulation of dephosphorylation 5 2.493591
GO:0035308 negative regulation of protein dephosphorylation 5 2.493591
GO:0048643 positive regulation of skeletal muscle tissue development 8 2.351958
GO:0001967 suckling behavior 8 2.282033
GO:0090257 regulation of muscle system process 90 2.28023
GO:0045980 negative regulation of nucleotide metabolic process 12 2.356923
GO:0010638 positive regulation of organelle organization 152 2.452669
GO:0052312 modulation of transcription in other organism involved in symbiotic interaction 13 2.236439
GO:0032875 regulation of DNA endoreduplication 5 2.414057
GO:0032876 negative regulation of DNA endoreduplication 5 2.414057
GO:0070934 CRD-mediated mRNA stabilization 5 2.405784
GO:0048515 spermatid differentiation 70 2.248614
GO:0045956 positive regulation of calcium ion-dependent exocytosis 9 2.415731
GO:0045932 negative regulation of muscle contraction 12 2.336087
GO:0033057 multicellular organismal reproductive behavior 12 2.293102
GO:0043488 regulation of mRNA stability 31 2.18848
GO:0009799 specification of symmetry 68 2.37249
GO:0030917 midbrain-hindbrain boundary development 10 2.255378
GO:0072234 metanephric nephron tubule development 10 2.239638
GO:0072243 metanephric nephron epithelium development 10 2.239638
GO:0090189 regulation of branching involved in ureteric bud morphogenesis 17 2.199003
GO:0001889 liver development 73 2.599098
GO:0006901 vesicle coating 25 2.236852
GO:0007224 smoothened signaling pathway 33 2.427353
GO:0009649 entrainment of circadian clock 8 2.27052
GO:0051386 regulation of nerve growth factor receptor signaling pathway 8 2.222194
GO:0009712 catechol metabolic process 39 2.296079
GO:0034311 diol metabolic process 39 2.296079
GO:0051017 actin filament bundle assembly 25 2.216259
GO:0048286 lung alveolus development 34 2.183206
GO:0021683 cerebellar granular layer morphogenesis 7 2.619945
GO:0006491 N-glycan processing 7 2.596005
GO:0060442 branching involved in prostate gland morphogenesis 11 2.261499
GO:0002790 peptide secretion 39 2.254411
GO:0033119 negative regulation of RNA splicing 11 2.242786
GO:0040017 positive regulation of locomotion 178 1.874623
GO:0045104 intermediate filament cytoskeleton organization 23 2.155166
GO:0072503 cellular divalent inorganic cation homeostasis 200 2.315341
GO:0035412 regulation of catenin import into nucleus 19 2.199732
GO:0021532 neural tube patterning 26 2.402411
GO:0003197 endocardial cushion development 9 2.390913
GO:0042416 dopamine biosynthetic process 9 2.380607
GO:0046426 negative regulation of JAK-STAT cascade 9 2.341223
GO:0031623 receptor internalization 23 2.11427
GO:0035710 CD4-positive, alpha-beta T cell activation 10 2.212078
GO:0045930 negative regulation of mitotic cell cycle 22 2.29884
GO:0010656 negative regulation of muscle cell apoptosis 11 2.190075
GO:0043584 nose development 11 2.181948
GO:0014032 neural crest cell development 43 2.538179
GO:0000910 cytokinesis 62 2.088185
GO:0071363 cellular response to growth factor stimulus 68 2.324386
GO:0070536 protein K63-linked deubiquitination 12 2.030661
GO:0006479 protein methylation 66 2.174746
GO:0008213 protein alkylation 66 2.174746
GO:0007440 foregut morphogenesis 11 2.166482
GO:0010171 body morphogenesis 27 2.178516
GO:2000677 regulation of transcription regulatory region DNA binding 8 2.179874
GO:0060251 regulation of glial cell proliferation 8 2.179459
GO:0002040 sprouting angiogenesis 18 2.329701
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 34 2.153529
GO:0046822 regulation of nucleocytoplasmic transport 115 2.075684
GO:0051590 positive regulation of neurotransmitter transport 6 2.737426
GO:0002072 optic cup morphogenesis involved in camera-type eye development 6 2.719415
GO:2000020 positive regulation of male gonad development 6 2.683168
GO:0050906 detection of stimulus involved in sensory perception 83 2.3353
GO:2000243 positive regulation of reproductive process 83 2.270705
GO:0072507 divalent inorganic cation homeostasis 208 2.147486
GO:0030072 peptide hormone secretion 36 2.387483
GO:0051953 negative regulation of amine transport 14 2.433536
GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure 14 2.41941
GO:0007431 salivary gland development 29 2.075025
GO:0051146 striated muscle cell differentiation 110 1.928318
GO:0032768 regulation of monooxygenase activity 40 2.264518
GO:0072210 metanephric nephron development 18 2.250295
GO:0045785 positive regulation of cell adhesion 95 2.101801
GO:0006875 cellular metal ion homeostasis 271 1.964762
GO:0030432 peristalsis 8 2.144955
GO:0021681 cerebellar granular layer development 8 2.134936
GO:0006096 glycolysis 45 1.944905
GO:0071900 regulation of protein serine/threonine kinase activity 303 2.247178
GO:0043535 regulation of blood vessel endothelial cell migration 30 2.150867
GO:0009583 detection of light stimulus 41 2.260872
GO:0021680 cerebellar Purkinje cell layer development 14 2.271539
GO:0035088 establishment or maintenance of apical/basal cell polarity 16 2.186216
GO:0061245 establishment or maintenance of bipolar cell polarity 16 2.186216
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 13 2.204895
GO:2000142 regulation of transcription initiation, DNA-dependent 13 2.204895
GO:0060428 lung epithelium development 20 2.048694
GO:0072028 nephron morphogenesis 20 2.02815
GO:0007062 sister chromatid cohesion 20 1.982432
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 20 1.937297
GO:0071241 cellular response to inorganic substance 53 2.146641
GO:0000216 M/G1 transition of mitotic cell cycle 79 2.354788
GO:0033145 positive regulation of steroid hormone receptor signaling pathway 6 2.61473
GO:0007368 determination of left/right symmetry 64 2.233293
GO:0012502 induction of programmed cell death 350 1.981817
GO:0043949 regulation of cAMP-mediated signaling 9 2.30522
GO:0048532 anatomical structure arrangement 9 2.291007
GO:0045646 regulation of erythrocyte differentiation 23 1.992219
GO:0006897 endocytosis 240 2.160423
GO:0010324 membrane invagination 240 2.160423
GO:0016574 histone ubiquitination 28 2.101453
GO:0033169 histone H3-K9 demethylation 7 2.555797
GO:0051938 L-glutamate import 6 2.597138
GO:0051584 regulation of dopamine uptake 6 2.595238
GO:0051940 regulation of catecholamine uptake involved in synaptic transmission 6 2.595238
GO:0033962 cytoplasmic mRNA processing body assembly 6 2.565669
GO:0014050 negative regulation of glutamate secretion 6 2.541797
GO:0051901 positive regulation of mitochondrial depolarization 5 2.358806
GO:0048545 response to steroid hormone stimulus 298 1.9095
GO:0007595 lactation 31 1.895861
GO:0051937 catecholamine transport 8 2.130047
GO:0060325 face morphogenesis 19 1.957278
GO:0072088 nephron epithelium morphogenesis 19 1.93889
GO:0051145 smooth muscle cell differentiation 19 1.919533
GO:0042537 benzene-containing compound metabolic process 63 2.035224
GO:0014850 response to muscle activity 7 2.439682
GO:0061303 cornea development in camera-type eye 6 2.485849
GO:0021684 cerebellar granular layer formation 6 2.478005
GO:0021707 cerebellar granule cell differentiation 6 2.478005
GO:0045292 nuclear mRNA cis splicing, via spliceosome 6 2.472001
GO:0071542 dopaminergic neuron differentiation 6 2.462522
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 6 2.425248
GO:0042754 negative regulation of circadian rhythm 6 2.425248
GO:0032099 negative regulation of appetite 6 2.416819
GO:0021559 trigeminal nerve development 6 2.410881
GO:0021797 forebrain anterior/posterior pattern formation 6 2.405623
GO:0030852 regulation of granulocyte differentiation 11 2.127644
GO:0042053 regulation of dopamine metabolic process 11 2.110683
GO:0060219 camera-type eye photoreceptor cell differentiation 11 2.092873
GO:0072170 metanephric tubule development 11 2.092739
GO:0007090 regulation of S phase of mitotic cell cycle 20 1.908231
GO:0042493 response to drug 340 1.871709
GO:0001840 neural plate development 7 2.416742
GO:0060601 lateral sprouting from an epithelium 7 2.368595
GO:0043149 stress fiber assembly 7 2.356672
GO:0050685 positive regulation of mRNA processing 7 2.354665
GO:0021830 interneuron migration from the subpallium to the cortex 5 2.322645
GO:0021853 cerebral cortex GABAergic interneuron migration 5 2.322645
GO:0021894 cerebral cortex GABAergic interneuron development 5 2.322645
GO:0032222 regulation of synaptic transmission, cholinergic 5 2.260936
GO:0072017 distal tubule development 5 2.256935
GO:0072025 distal convoluted tubule development 5 2.256935
GO:0072221 metanephric distal convoluted tubule development 5 2.256935
GO:0072235 metanephric distal tubule development 5 2.256935
GO:0021978 telencephalon regionalization 5 2.232477
GO:0032874 positive regulation of stress-activated MAPK cascade 14 2.173122
GO:0042136 neurotransmitter biosynthetic process 14 2.171943
GO:0014821 phasic smooth muscle contraction 14 2.165246
GO:0035196 production of miRNAs involved in gene silencing by miRNA 14 2.148912
GO:0042481 regulation of odontogenesis 17 2.11844
GO:0042133 neurotransmitter metabolic process 25 2.050392
GO:0043487 regulation of RNA stability 33 2.29132
GO:0072009 nephron epithelium development 24 2.105609
GO:0006942 regulation of striated muscle contraction 29 1.951649
GO:0032012 regulation of ARF protein signal transduction 48 1.956094
GO:0043951 negative regulation of cAMP-mediated signaling 5 2.222703
GO:0002042 cell migration involved in sprouting angiogenesis 5 2.214587
GO:0060789 hair follicle placode formation 5 2.173962
GO:0048534 hemopoietic or lymphoid organ development 296 2.121209
GO:0021511 spinal cord patterning 16 2.104941
GO:0016441 posttranscriptional gene silencing 26 2.179322
GO:0035194 posttranscriptional gene silencing by RNA 26 2.179322
GO:0072207 metanephric epithelium development 12 1.957969
GO:0006301 postreplication repair 12 1.926086
GO:0031998 regulation of fatty acid beta-oxidation 11 2.012748
GO:0051155 positive regulation of striated muscle cell differentiation 9 2.247546
GO:0070167 regulation of biomineral tissue development 49 2.036959
GO:0001525 angiogenesis 188 2.243088
GO:0009991 response to extracellular stimulus 348 2.059998
GO:0032411 positive regulation of transporter activity 25 2.032179
GO:0043526 neuroprotection 25 1.980255
GO:0030835 negative regulation of actin filament depolymerization 25 1.977898
GO:0035304 regulation of protein dephosphorylation 13 2.156973
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 18 2.161926
GO:0032096 negative regulation of response to food 7 2.266616
GO:0016081 synaptic vesicle docking involved in exocytosis 7 2.233798
GO:0006590 thyroid hormone generation 7 2.23181
GO:0001574 ganglioside biosynthetic process 7 2.231549
GO:0019054 modulation by virus of host cellular process 7 2.210114
GO:0048148 behavioral response to cocaine 7 2.197149
GO:0002224 toll-like receptor signaling pathway 87 1.998424
GO:0009145 purine nucleoside triphosphate biosynthetic process 84 1.731235
GO:0009201 ribonucleoside triphosphate biosynthetic process 84 1.729962
GO:0042940 D-amino acid transport 5 2.112425
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 5 2.106792
GO:0033148 positive regulation of estrogen receptor signaling pathway 5 2.103586
GO:0045807 positive regulation of endocytosis 54 2.220755
GO:0033273 response to vitamin 148 2.284094
GO:0016458 gene silencing 73 2.371432
GO:0048871 multicellular organismal homeostasis 85 1.816739
GO:0043084 penile erection 5 2.068574
GO:0031915 positive regulation of synaptic plasticity 7 2.168431
GO:0070170 regulation of tooth mineralization 7 2.158969
GO:2000018 regulation of male gonad development 7 2.150663
GO:0045836 positive regulation of meiosis 7 2.144495
GO:0031936 negative regulation of chromatin silencing 7 2.131837
GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 7 2.117137
GO:0006937 regulation of muscle contraction 77 2.004408
GO:0014002 astrocyte development 9 2.24366
GO:0031935 regulation of chromatin silencing 9 2.220103
GO:0010463 mesenchymal cell proliferation 9 2.184012
GO:0060766 negative regulation of androgen receptor signaling pathway 9 2.164405
GO:0060389 pathway-restricted SMAD protein phosphorylation 12 1.888407
GO:0010923 negative regulation of phosphatase activity 7 2.043503
GO:0031054 pre-microRNA processing 7 2.02909
GO:0060124 positive regulation of growth hormone secretion 7 1.995538
GO:0006337 nucleosome disassembly 7 1.994158
GO:0031498 chromatin disassembly 7 1.994158
GO:0032986 protein-DNA complex disassembly 7 1.994158
GO:0072283 metanephric renal vesicle morphogenesis 7 1.949719
GO:0003309 type B pancreatic cell differentiation 7 1.908474
GO:0010092 specification of organ identity 7 1.899426
GO:0007286 spermatid development 67 2.271414
GO:0031050 dsRNA fragmentation 15 1.989938
GO:0070918 production of small RNA involved in gene silencing by RNA 15 1.989938
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 15 1.981418
GO:0007602 phototransduction 34 1.964952
GO:0010811 positive regulation of cell-substrate adhesion 44 2.016743
GO:0000084 S phase of mitotic cell cycle 114 1.88224
GO:0002763 positive regulation of myeloid leukocyte differentiation 27 2.094623
GO:0016049 cell growth 82 2.024461
GO:0006892 post-Golgi vesicle-mediated transport 63 1.764241
GO:0003018 vascular process in circulatory system 63 1.709237
GO:0061384 heart trabecular morphogenesis 8 2.078383
GO:0048340 paraxial mesoderm morphogenesis 8 1.988229
GO:0007184 SMAD protein import into nucleus 7 1.865551
GO:0021520 spinal cord motor neuron cell fate specification 7 1.85641
GO:0008343 adult feeding behavior 7 1.849561
GO:0032891 negative regulation of organic acid transport 7 1.834011
GO:0051654 establishment of mitochondrion localization 7 1.821211
GO:0007091 mitotic metaphase/anaphase transition 13 2.091001
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 5 2.046763
GO:0060510 Type II pneumocyte differentiation 5 2.043497
GO:0006605 protein targeting 212 1.956369
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 83 1.841221
GO:0035567 non-canonical Wnt receptor signaling pathway 24 2.039599
GO:0006305 DNA alkylation 33 2.016106
GO:0006306 DNA methylation 33 2.016106
GO:0042069 regulation of catecholamine metabolic process 12 1.874934
GO:0007266 Rho protein signal transduction 46 1.980772
GO:0044341 sodium-dependent phosphate transport 5 2.015745
GO:0010919 regulation of inositol phosphate biosynthetic process 5 2.001376
GO:0007343 egg activation 5 1.98943
GO:0050951 sensory perception of temperature stimulus 5 1.95356
GO:0045578 negative regulation of B cell differentiation 5 1.918593
GO:0010739 positive regulation of protein kinase A signaling cascade 5 1.916896
GO:0007501 mesodermal cell fate specification 5 1.91019
GO:0022038 corpus callosum development 5 1.894282
GO:0033151 V(D)J recombination 12 1.775735
GO:0051693 actin filament capping 23 1.830152
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 32 2.238875
GO:0030073 insulin secretion 26 2.007071
GO:0007584 response to nutrient 223 1.884183
GO:0001570 vasculogenesis 51 2.150893
GO:0071560 cellular response to transforming growth factor beta stimulus 18 2.000042
GO:0034394 protein localization at cell surface 18 1.999565
GO:0000060 protein import into nucleus, translocation 18 1.964818
GO:0060897 neural plate regionalization 6 2.377117
GO:0015810 aspartate transport 6 2.374357
GO:0031657 regulation of cyclin-dependent protein kinase activity involved by G1/S 6 2.368626
GO:0006458 'de novo' protein folding 53 1.950078
GO:0072073 kidney epithelium development 30 2.002766
GO:0006817 phosphate transport 8 1.951938
GO:0030097 hemopoiesis 263 1.654512
GO:0018193 peptidyl-amino acid modification 373 1.938052
GO:0006917 induction of apoptosis 348 1.818112
GO:0048664 neuron fate determination 7 1.711797
GO:0010664 negative regulation of striated muscle cell apoptosis 7 1.703018
GO:0030041 actin filament polymerization 12 1.722765
GO:0071391 cellular response to estrogen stimulus 12 1.718107
GO:0060347 heart trabecula formation 7 1.665888
GO:0009123 nucleoside monophosphate metabolic process 84 1.605586
GO:0031053 primary microRNA processing 5 1.856206
GO:0031659 positive regulation of cyclin-dependent protein kinase activity involved in G1/S 5 1.793291
GO:0021548 pons development 6 2.343061
GO:0030388 fructose 1,6-bisphosphate metabolic process 6 2.324804
GO:0035176 social behavior 22 2.157651
GO:0061098 positive regulation of protein tyrosine kinase activity 22 2.111594
GO:0051099 positive regulation of binding 49 1.955632
GO:0031063 regulation of histone deacetylation 11 1.93268
GO:0007064 mitotic sister chromatid cohesion 8 1.861028
GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine 8 1.83911
GO:0019047 provirus integration 8 1.822122
GO:0030069 lysogeny 8 1.822122
GO:0035413 positive regulation of catenin import into nucleus 8 1.820693
GO:0031958 corticosteroid receptor signaling pathway 8 1.805944
GO:0042921 glucocorticoid receptor signaling pathway 8 1.805944
GO:0031062 positive regulation of histone methylation 8 1.800163
GO:0010662 regulation of striated muscle cell apoptosis 8 1.787631
GO:0033604 negative regulation of catecholamine secretion 8 1.783149
GO:0045662 negative regulation of myoblast differentiation 8 1.775665
GO:0043129 surfactant homeostasis 8 1.771575
GO:0048875 chemical homeostasis within a tissue 8 1.771575
GO:0048266 behavioral response to pain 8 1.760814
GO:0044068 modulation by symbiont of host cellular process 8 1.743261
GO:0009886 post-embryonic morphogenesis 8 1.73231
GO:0042753 positive regulation of circadian rhythm 8 1.730086
GO:0033233 regulation of protein sumoylation 8 1.727383
GO:0051569 regulation of histone H3-K4 methylation 8 1.726333
GO:0051568 histone H3-K4 methylation 12 1.653335
GO:0051272 positive regulation of cellular component movement 179 1.686765
GO:0009629 response to gravity 13 2.072524
GO:0043489 RNA stabilization 22 1.956651
GO:0048255 mRNA stabilization 22 1.956651
GO:0032239 regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport 5 1.778455
GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway 5 1.775884
GO:0034643 establishment of mitochondrion localization, microtubule-mediated 5 1.775241
GO:0047497 mitochondrion transport along microtubule 5 1.775241
GO:0035117 embryonic arm morphogenesis 5 1.77241
GO:0035140 arm morphogenesis 5 1.77241
GO:0090073 positive regulation of protein homodimerization activity 5 1.753957
GO:0021999 neural plate anterior/posterior regionalization 5 1.746828
GO:0070933 histone H4 deacetylation 5 1.73649
GO:0002327 immature B cell differentiation 5 1.736464
GO:0002329 pre-B cell differentiation 5 1.736464
GO:0060259 regulation of feeding behavior 7 1.655147
GO:0007320 insemination 12 1.620898
GO:0048146 positive regulation of fibroblast proliferation 33 1.845312
GO:0048730 epidermis morphogenesis 33 1.774668
GO:0006353 transcription termination, DNA-dependent 77 1.90112
GO:0043388 positive regulation of DNA binding 18 1.857305
GO:0014003 oligodendrocyte development 28 1.89468
GO:0051385 response to mineralocorticoid stimulus 28 1.883999
GO:0048066 developmental pigmentation 33 1.656136
GO:0060039 pericardium development 10 2.108418
GO:0070555 response to interleukin-1 51 1.953328
GO:0021859 pyramidal neuron differentiation 5 1.725279
GO:0021860 pyramidal neuron development 5 1.725279
GO:0042347 negative regulation of NF-kappaB import into nucleus 11 1.883078
GO:0055065 metal ion homeostasis 282 1.764595
GO:0051606 detection of stimulus 174 2.243879
GO:0060765 regulation of androgen receptor signaling pathway 16 2.004163
GO:0030878 thyroid gland development 16 1.956792
GO:0046543 development of secondary female sexual characteristics 8 1.679717
GO:0060693 regulation of branching involved in salivary gland morphogenesis 8 1.650916
GO:0043496 regulation of protein homodimerization activity 14 1.963277
GO:0010677 negative regulation of cellular carbohydrate metabolic process 14 1.92251
GO:0045912 negative regulation of carbohydrate metabolic process 14 1.92251
GO:0045600 positive regulation of fat cell differentiation 17 1.82781
GO:0030003 cellular cation homeostasis 297 1.765369
GO:0051781 positive regulation of cell division 45 1.733677
GO:0002064 epithelial cell development 53 1.885589
GO:0046636 negative regulation of alpha-beta T cell activation 14 1.869534
GO:0002221 pattern recognition receptor signaling pathway 96 1.651643
GO:0031667 response to nutrient levels 325 1.877903
GO:0006401 RNA catabolic process 118 1.855456
GO:0008217 regulation of blood pressure 118 1.82948
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity 133 1.598649
GO:0090047 positive regulation of transcription regulator activity 133 1.598649
GO:0031668 cellular response to extracellular stimulus 141 1.869562
GO:0071359 cellular response to dsRNA 25 1.70351
GO:0071826 ribonucleoprotein complex subunit organization 99 1.654582
GO:0072178 nephric duct morphogenesis 8 1.629038
GO:0014888 striated muscle adaptation 8 1.618266
GO:0032352 positive regulation of hormone metabolic process 12 1.608891
GO:0018108 peptidyl-tyrosine phosphorylation 36 1.783635
GO:0031102 neuron projection regeneration 20 1.744494
GO:0071902 positive regulation of protein serine/threonine kinase activity 176 1.74476
GO:0006940 regulation of smooth muscle contraction 39 1.976612
GO:0006007 glucose catabolic process 58 1.834643
GO:0070534 protein K63-linked ubiquitination 23 1.720074
GO:0046579 positive regulation of Ras protein signal transduction 24 1.941047
GO:0045103 intermediate filament-based process 24 1.929118
GO:0043506 regulation of JUN kinase activity 58 1.684676
GO:0043491 protein kinase B signaling cascade 13 1.911066
GO:0030431 sleep 13 1.903927
GO:0003209 cardiac atrium morphogenesis 13 1.883422
GO:0003230 cardiac atrium development 13 1.883422
GO:0060351 cartilage development involved in endochondral bone morphogenesis 13 1.882612
GO:0061005 cell differentiation involved in kidney development 13 1.848761
GO:0045737 positive regulation of cyclin-dependent protein kinase activity 13 1.749121
GO:0007620 copulation 17 1.736451
GO:0051954 positive regulation of amine transport 17 1.734085
GO:0032784 regulation of transcription elongation, DNA-dependent 20 1.727645
GO:0046782 regulation of viral transcription 58 1.596324
GO:0042401 cellular biogenic amine biosynthetic process 39 1.876777
GO:0072044 collecting duct development 7 1.631888
GO:0060206 estrous cycle phase 7 1.608887
GO:0035115 embryonic forelimb morphogenesis 26 1.854587
GO:0030540 female genitalia development 7 1.576475
GO:0001667 ameboidal cell migration 50 2.038011
GO:0055007 cardiac muscle cell differentiation 40 1.858922
GO:0032273 positive regulation of protein polymerization 40 1.711011
GO:0019695 choline metabolic process 5 1.663515
GO:0060438 trachea development 13 1.635265
GO:0043666 regulation of phosphoprotein phosphatase activity 21 2.185419
GO:0071396 cellular response to lipid 21 2.170725
GO:0048485 sympathetic nervous system development 21 2.158781
GO:0031334 positive regulation of protein complex assembly 72 1.784413
GO:0048259 regulation of receptor-mediated endocytosis 31 1.659608
GO:0015988 energy coupled proton transport, against electrochemical gradient 31 1.581702
GO:0015991 ATP hydrolysis coupled proton transport 31 1.581702
GO:0000338 protein deneddylation 9 2.094037
GO:0010388 cullin deneddylation 9 2.094037
GO:0051593 response to folic acid 9 1.953805
GO:0022409 positive regulation of cell-cell adhesion 23 1.577449
GO:0051412 response to corticosterone stimulus 23 1.509328
GO:0006833 water transport 35 1.896852
GO:0010038 response to metal ion 219 1.627254
GO:0042326 negative regulation of phosphorylation 73 2.055389
GO:0032091 negative regulation of protein binding 25 1.676867
GO:0051492 regulation of stress fiber assembly 25 1.599135
GO:0046839 phospholipid dephosphorylation 10 2.014324
GO:0010035 response to inorganic substance 328 1.782606
GO:0048844 artery morphogenesis 20 1.6503
GO:0032355 response to estradiol stimulus 98 1.852404
GO:0030500 regulation of bone mineralization 44 1.668226
GO:0045741 positive regulation of epidermal growth factor receptor activity 10 1.966162
GO:0060638 mesenchymal-epithelial cell signaling 9 1.92759
GO:0046823 negative regulation of nucleocytoplasmic transport 38 1.831524
GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine 7 1.541406
GO:0032000 positive regulation of fatty acid beta-oxidation 7 1.486975
GO:0051148 negative regulation of muscle cell differentiation 19 1.671744
GO:0030279 negative regulation of ossification 16 1.9333
GO:0061383 trabecula morphogenesis 16 1.911008
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 17 1.632165
GO:0010470 regulation of gastrulation 17 1.613049
GO:0042670 retinal cone cell differentiation 7 1.460269
GO:0046549 retinal cone cell development 7 1.460269
GO:0045116 protein neddylation 7 1.445796
GO:0033235 positive regulation of protein sumoylation 7 1.437081
GO:0042415 norepinephrine metabolic process 7 1.426053
GO:0048145 regulation of fibroblast proliferation 47 1.76894
GO:0050821 protein stabilization 47 1.748995
GO:0010837 regulation of keratinocyte proliferation 7 1.386177
GO:0090342 regulation of cell aging 7 1.381261
GO:0022601 menstrual cycle phase 7 1.349849
GO:0002320 lymphoid progenitor cell differentiation 7 1.349276
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 56 1.70925
GO:0022407 regulation of cell-cell adhesion 44 1.610285
GO:0046209 nitric oxide metabolic process 23 1.491229
GO:0060795 cell fate commitment involved in formation of primary germ layers 20 1.584782
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 20 1.502973
GO:0042733 embryonic digit morphogenesis 35 1.824292
GO:0050434 positive regulation of viral transcription 51 1.764097
GO:0006576 cellular biogenic amine metabolic process 117 1.530583
GO:0031669 cellular response to nutrient levels 117 1.510618
GO:0060674 placenta blood vessel development 18 1.76529
GO:0009750 response to fructose stimulus 8 1.574637
GO:0034260 negative regulation of GTPase activity 8 1.568911
GO:0030579 ubiquitin-dependent SMAD protein catabolic process 5 1.601008
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 5 1.597467
GO:0048069 eye pigmentation 5 1.542161
GO:2000147 positive regulation of cell motility 170 1.680837
GO:0042738 exogenous drug catabolic process 9 1.898972
GO:0072077 renal vesicle morphogenesis 9 1.850218
GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter 9 1.826011
GO:0002063 chondrocyte development 9 1.753841
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 50 1.726329
GO:0051927 negative regulation of calcium ion transport via voltage-gated calcium channel activity 9 1.720644
GO:0002686 negative regulation of leukocyte migration 9 1.714747
GO:0001755 neural crest cell migration 29 1.668216
GO:0007204 elevation of cytosolic calcium ion concentration 121 1.93415
GO:0016050 vesicle organization 74 1.920378
GO:0016571 histone methylation 49 1.744834
GO:0010595 positive regulation of endothelial cell migration 33 1.597749
GO:0008015 blood circulation 210 1.52965
GO:0031047 gene silencing by RNA 43 1.744353
GO:0048536 spleen development 19 1.653404
GO:0033522 histone H2A ubiquitination 12 1.520568
GO:0060272 embryonic skeletal joint morphogenesis 8 1.508933
GO:0016575 histone deacetylation 21 1.849358
GO:0072215 regulation of metanephros development 17 1.553467
GO:0032872 regulation of stress-activated MAPK cascade 20 1.43676
GO:0060445 branching involved in salivary gland morphogenesis 15 1.71095
GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway 11 1.670739
GO:0090175 regulation of establishment of planar polarity 11 1.670739
GO:0001706 endoderm formation 14 1.625452
GO:0071695 anatomical structure maturation 26 1.587651
GO:0006476 protein deacetylation 26 1.546514
GO:0031532 actin cytoskeleton reorganization 26 1.512791
GO:0001541 ovarian follicle development 49 1.641008
GO:0090317 negative regulation of intracellular protein transport 42 1.603214
GO:0030856 regulation of epithelial cell differentiation 42 1.526361
GO:0006094 gluconeogenesis 41 1.800222
GO:0015844 monoamine transport 17 1.498667
GO:0072079 nephron tubule formation 12 1.477157
GO:0001573 ganglioside metabolic process 12 1.476352
GO:0045185 maintenance of protein location 85 1.421664
GO:0060323 head morphogenesis 21 1.793067
GO:0048645 organ formation 21 1.734957
GO:0046626 regulation of insulin receptor signaling pathway 22 1.638383
GO:0060135 maternal process involved in female pregnancy 21 1.617335
GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway 26 1.482395
GO:0042755 eating behavior 26 1.423597
GO:0032414 positive regulation of ion transmembrane transporter activity 22 1.554386
GO:0043502 regulation of muscle adaptation 19 1.638056
GO:0033157 regulation of intracellular protein transport 112 1.38577
GO:0002762 negative regulation of myeloid leukocyte differentiation 25 1.571365
GO:0032092 positive regulation of protein binding 25 1.481652
GO:0006164 purine nucleotide biosynthetic process 138 1.819605
GO:0060592 mammary gland formation 6 2.288688
GO:0045814 negative regulation of gene expression, epigenetic 27 1.762772
GO:0006513 protein monoubiquitination 27 1.731009
GO:0030335 positive regulation of cell migration 169 1.681259
GO:0051896 regulation of protein kinase B signaling cascade 54 1.434774
GO:0048588 developmental cell growth 30 1.808743
GO:0032886 regulation of microtubule-based process 67 1.80637
GO:0032231 regulation of actin filament bundle assembly 30 1.80312
GO:0043270 positive regulation of ion transport 67 1.745848
GO:0043414 macromolecule methylation 106 1.547716
GO:0035518 histone H2A monoubiquitination 7 1.271713
GO:0050847 progesterone receptor signaling pathway 5 1.534152
GO:0060484 lung-associated mesenchyme development 9 1.632844
GO:0051495 positive regulation of cytoskeleton organization 75 1.617093
GO:0032507 maintenance of protein location in cell 75 1.574677
GO:0006939 smooth muscle contraction 32 1.72019
GO:0010453 regulation of cell fate commitment 22 1.49379
GO:0055080 cation homeostasis 337 1.206316
GO:0007097 nuclear migration 6 2.236585
GO:0016322 neuron remodeling 6 2.209996
GO:0042310 vasoconstriction 14 1.606952
GO:0008211 glucocorticoid metabolic process 14 1.589776
GO:0006835 dicarboxylic acid transport 14 1.537014
GO:0007379 segment specification 14 1.474619
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 14 1.423319
GO:0001502 cartilage condensation 14 1.371366
GO:0050792 regulation of viral reproduction 79 1.339907
GO:0051320 S phase 125 1.764539
GO:0010506 regulation of autophagy 15 1.602984
GO:0071456 cellular response to hypoxia 32 1.597132
GO:0060343 trabecula formation 15 1.593863
GO:0071599 otic vesicle development 12 1.431855
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 12 1.37008
GO:0042403 thyroid hormone metabolic process 12 1.369579
GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger 12 1.367863
GO:0048714 positive regulation of oligodendrocyte differentiation 9 1.58259
GO:0010922 positive regulation of phosphatase activity 9 1.5485
GO:0032465 regulation of cytokinesis 9 1.545182
GO:0030851 granulocyte differentiation 9 1.542996
GO:0048387 negative regulation of retinoic acid receptor signaling pathway 8 1.433276
GO:0031065 positive regulation of histone deacetylation 8 1.400692
GO:0021514 ventral spinal cord interneuron differentiation 8 1.390365
GO:0060579 ventral spinal cord interneuron fate commitment 8 1.390365
GO:0010870 positive regulation of receptor biosynthetic process 7 1.213227
GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 7 1.202056
GO:0051608 histamine transport 7 1.188334
GO:0010665 regulation of cardiac muscle cell apoptosis 7 1.186034
GO:0071453 cellular response to oxygen levels 35 1.680097
GO:0042044 fluid transport 38 1.527676
GO:0018212 peptidyl-tyrosine modification 38 1.510812
GO:0072176 nephric duct development 9 1.508569
GO:0046851 negative regulation of bone remodeling 9 1.488136
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 9 1.471977
GO:0071636 positive regulation of transforming growth factor-beta production 9 1.440537
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 6 2.173854
GO:0060986 endocrine hormone secretion 6 2.158056
GO:0060253 negative regulation of glial cell proliferation 6 2.144619
GO:0021554 optic nerve development 6 2.119356
GO:0006342 chromatin silencing 24 1.600408
GO:0048675 axon extension 22 1.464234
GO:0046850 regulation of bone remodeling 22 1.455654
GO:0060840 artery development 22 1.439539
GO:0042311 vasodilation 22 1.331332
GO:0006367 transcription initiation from RNA polymerase II promoter 68 1.584597
GO:0045777 positive regulation of blood pressure 35 1.453269
GO:0016584 nucleosome positioning 5 1.525221
GO:0000380 alternative nuclear mRNA splicing, via spliceosome 5 1.493661
GO:0043353 enucleate erythrocyte differentiation 5 1.490238
GO:0010624 regulation of Schwann cell proliferation 5 1.471597
GO:0006997 nucleus organization 38 1.439557
GO:0051900 regulation of mitochondrial depolarization 9 1.403037
GO:0072080 nephron tubule development 18 1.604924
GO:0043114 regulation of vascular permeability 18 1.537953
GO:0048484 enteric nervous system development 18 1.530914
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 18 1.519808
GO:0032835 glomerulus development 18 1.500595
GO:0071392 cellular response to estradiol stimulus 8 1.317782
GO:0048013 ephrin receptor signaling pathway 8 1.317124
GO:0007217 tachykinin receptor signaling pathway 8 1.30919
GO:0060491 regulation of cell projection assembly 36 1.508143
GO:0001839 neural plate morphogenesis 5 1.467584
GO:0060534 trachea cartilage development 5 1.465745
GO:0060415 muscle tissue morphogenesis 39 1.399397
GO:0060969 negative regulation of gene silencing 9 1.38291
GO:0002634 regulation of germinal center formation 9 1.359858
GO:0030010 establishment of cell polarity 39 1.34522
GO:0050872 white fat cell differentiation 9 1.338311
GO:0048703 embryonic viscerocranium morphogenesis 9 1.31889
GO:0031331 positive regulation of cellular catabolic process 73 1.553758
GO:0043406 positive regulation of MAP kinase activity 146 1.201085
GO:0022408 negative regulation of cell-cell adhesion 16 1.714395
GO:0010660 regulation of muscle cell apoptosis 16 1.7098
GO:0071514 genetic imprinting 16 1.579935
GO:0009581 detection of external stimulus 76 1.648296
GO:0009142 nucleoside triphosphate biosynthetic process 86 1.629779
GO:0030834 regulation of actin filament depolymerization 29 1.43758
GO:0010564 regulation of cell cycle process 355 1.300395
GO:0061326 renal tubule development 19 1.565452
GO:0043536 positive regulation of blood vessel endothelial cell migration 19 1.497773
GO:0007398 ectoderm development 18 1.436735
GO:0014902 myotube differentiation 19 1.401737
GO:0070972 protein localization in endoplasmic reticulum 18 1.373628
GO:0045823 positive regulation of heart contraction 21 1.468418
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway 5 1.462402
GO:0032854 positive regulation of Rap GTPase activity 5 1.434789
GO:0048260 positive regulation of receptor-mediated endocytosis 21 1.42761
GO:0045884 regulation of survival gene product expression 21 1.425646
GO:0007205 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway 38 1.377756
GO:0090183 regulation of kidney development 44 1.55022
GO:0072179 nephric duct formation 5 1.42395
GO:0003215 cardiac right ventricle morphogenesis 5 1.423547
GO:0043301 negative regulation of leukocyte degranulation 5 1.415684
GO:0035767 endothelial cell chemotaxis 5 1.413317
GO:0032225 regulation of synaptic transmission, dopaminergic 15 1.284949
GO:0042992 negative regulation of transcription factor import into nucleus 23 1.242558
GO:0048617 embryonic foregut morphogenesis 10 1.906515
GO:0048200 Golgi transport vesicle coating 10 1.897598
GO:0048205 COPI coating of Golgi vesicle 10 1.897598
GO:0072087 renal vesicle development 10 1.856757
GO:0060317 cardiac epithelial to mesenchymal transition 10 1.760307
GO:0032786 positive regulation of transcription elongation, DNA-dependent 10 1.743048
GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway 10 1.671044
GO:0010591 regulation of lamellipodium assembly 10 1.667092
GO:0033365 protein localization to organelle 224 1.416841
GO:0061333 renal tubule morphogenesis 14 1.325546
GO:0042659 regulation of cell fate specification 14 1.301681
GO:0035336 long-chain fatty-acyl-CoA metabolic process 18 1.320324
GO:0035338 long-chain fatty-acyl-CoA biosynthetic process 18 1.320324
GO:0048854 brain morphogenesis 18 1.307023
GO:0042487 regulation of odontogenesis of dentine-containing tooth 7 1.169325
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 7 1.158345
GO:0060033 anatomical structure regression 7 1.153976
GO:0010830 regulation of myotube differentiation 7 1.150105
GO:0072074 kidney mesenchyme development 7 1.130838
GO:0072075 metanephric mesenchyme development 7 1.130838
GO:0007606 sensory perception of chemical stimulus 117 1.017413
GO:0015833 peptide transport 53 1.607269
GO:0010948 negative regulation of cell cycle process 71 1.187185
GO:0032846 positive regulation of homeostatic process 60 1.441636
GO:0002758 innate immune response-activating signal transduction 99 1.369864
GO:0035112 genitalia morphogenesis 11 1.593642
GO:0006895 Golgi to endosome transport 11 1.571275
GO:0033261 regulation of S phase 28 1.489428
GO:0002520 immune system development 324 1.553505
GO:0071436 sodium ion export 5 1.385064
GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 5 1.368598
GO:0046621 negative regulation of organ growth 5 1.350553
GO:2000050 regulation of non-canonical Wnt receptor signaling pathway 5 1.341064
GO:0021604 cranial nerve structural organization 5 1.331546
GO:0060872 semicircular canal development 5 1.331516
GO:2000344 positive regulation of acrosome reaction 5 1.328181
GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway 5 1.311101
GO:0045906 negative regulation of vasoconstriction 5 1.307608
GO:0072124 regulation of glomerular mesangial cell proliferation 5 1.296139
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 23 1.207386
GO:0019048 virus-host interaction 37 1.801149
GO:0006664 glycolipid metabolic process 37 1.553669
GO:0090103 cochlea morphogenesis 12 1.344939
GO:0055003 cardiac myofibril assembly 12 1.331706
GO:2000273 positive regulation of receptor activity 12 1.328293
GO:0003170 heart valve development 12 1.288114
GO:0045136 development of secondary sexual characteristics 9 1.286036
GO:0060396 growth hormone receptor signaling pathway 9 1.268121
GO:0071378 cellular response to growth hormone stimulus 9 1.268121
GO:0035066 positive regulation of histone acetylation 12 1.267897
GO:0006265 DNA topological change 9 1.26398
GO:0002016 regulation of blood volume by renin-angiotensin 9 1.25289
GO:0001711 endodermal cell fate commitment 5 1.271069
GO:0003306 Wnt receptor signaling pathway involved in heart development 5 1.263187
GO:0060017 parathyroid gland development 5 1.253212
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 5 1.251635
GO:2000036 regulation of stem cell maintenance 5 1.242632
GO:0090030 regulation of steroid hormone biosynthetic process 10 1.612115
GO:0048524 positive regulation of viral reproduction 67 1.533461
GO:0007625 grooming behavior 10 1.520328
GO:0048385 regulation of retinoic acid receptor signaling pathway 10 1.50574
GO:0043193 positive regulation of gene-specific transcription 10 1.460513
GO:0010524 positive regulation of calcium ion transport into cytosol 25 1.430449
GO:0070830 tight junction assembly 28 1.39569
GO:0007257 activation of JUN kinase activity 31 1.327419
GO:0016486 peptide hormone processing 25 1.324981
GO:0006182 cGMP biosynthetic process 15 1.258898
GO:0060297 regulation of sarcomere organization 5 1.231275
GO:0042473 outer ear morphogenesis 5 1.228408
GO:0042634 regulation of hair cycle 8 1.220303
GO:0032811 negative regulation of epinephrine secretion 5 1.214086
GO:0051387 negative regulation of nerve growth factor receptor signaling pathway 5 1.213772
GO:0048857 neural nucleus development 8 1.208496
GO:0016048 detection of temperature stimulus 5 1.205457
GO:0051955 regulation of amino acid transport 8 1.204304
GO:0010592 positive regulation of lamellipodium assembly 5 1.191541
GO:0035307 positive regulation of protein dephosphorylation 8 1.188363
GO:0032525 somite rostral/caudal axis specification 5 1.18356
GO:0022417 protein maturation by protein folding 5 1.128798
GO:0051156 glucose 6-phosphate metabolic process 5 1.107277
GO:0046548 retinal rod cell development 5 1.102952
GO:0032317 regulation of Rap GTPase activity 6 2.095613
GO:0032487 regulation of Rap protein signal transduction 6 2.095613
GO:0003148 outflow tract septum morphogenesis 6 2.084841
GO:0061001 regulation of dendritic spine morphogenesis 6 2.069311
GO:0032232 negative regulation of actin filament bundle assembly 6 2.03812
GO:0043497 regulation of protein heterodimerization activity 6 2.025189
GO:0060023 soft palate development 6 1.973796
GO:0045924 regulation of female receptivity 6 1.95004
GO:0060180 female mating behavior 6 1.95004
GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback 6 1.913213
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 6 1.895519
GO:0055075 potassium ion homeostasis 6 1.892586
GO:0090344 negative regulation of cell aging 6 1.862635
GO:0090083 regulation of inclusion body assembly 6 1.857502
GO:0003013 circulatory system process 211 1.606363
GO:0048661 positive regulation of smooth muscle cell proliferation 35 1.343844
GO:0051258 protein polymerization 49 1.424939
GO:0014067 negative regulation of phosphatidylinositol 3-kinase cascade 7 1.11013
GO:0061024 membrane organization 467 1.333786
GO:0048741 skeletal muscle fiber development 32 0.960013
GO:0060745 mammary gland branching involved in pregnancy 6 1.834735
GO:0072205 metanephric collecting duct development 6 1.820419
GO:0032924 activin receptor signaling pathway 6 1.812346
GO:0032104 regulation of response to extracellular stimulus 16 1.417509
GO:0032107 regulation of response to nutrient levels 16 1.417509
GO:0070271 protein complex biogenesis 492 1.338973
GO:0033138 positive regulation of peptidyl-serine phosphorylation 31 1.315272
GO:0001933 negative regulation of protein phosphorylation 56 1.348004
GO:0060040 retinal bipolar neuron differentiation 5 1.086317
GO:0032278 positive regulation of gonadotropin secretion 5 1.077273
GO:0046881 positive regulation of follicle-stimulating hormone secretion 5 1.077273
GO:0006818 hydrogen transport 66 0.846252
GO:0051591 response to cAMP 68 1.506926
GO:0017038 protein import 131 1.385761
GO:0051302 regulation of cell division 61 1.357168
GO:0034622 cellular macromolecular complex assembly 427 1.174399
GO:0045747 positive regulation of Notch signaling pathway 7 1.059114
GO:0070227 lymphocyte apoptosis 7 1.022337
GO:0043922 negative regulation by host of viral transcription 7 1.010584
GO:0031647 regulation of protein stability 74 1.539043
GO:0055067 monovalent inorganic cation homeostasis 44 1.412829
GO:0032387 negative regulation of intracellular transport 44 1.366232
GO:0001947 heart looping 35 1.299226
GO:0003143 embryonic heart tube morphogenesis 35 1.299226
GO:0061371 determination of heart left/right asymmetry 35 1.299226
GO:0090184 positive regulation of kidney development 18 1.190879
GO:0032259 methylation 117 0.882729
GO:0032331 negative regulation of chondrocyte differentiation 10 1.39117
GO:0042693 muscle cell fate commitment 10 1.384906
GO:0035725 sodium ion transmembrane transport 10 1.383891
GO:0043921 modulation by host of viral transcription 10 1.3461
GO:0052472 modulation by host of symbiont transcription 10 1.3461
GO:0007020 microtubule nucleation 10 1.345092
GO:0051000 positive regulation of nitric-oxide synthase activity 10 1.337647
GO:0046321 positive regulation of fatty acid oxidation 10 1.335536
GO:0050690 regulation of defense response to virus by virus 28 1.321665
GO:0000768 syncytium formation by plasma membrane fusion 10 1.312531
GO:0007520 myoblast fusion 10 1.312531
GO:0014823 response to activity 36 1.179099
GO:0043331 response to dsRNA 36 1.144799
GO:0043966 histone H3 acetylation 41 1.345998
GO:0008334 histone mRNA metabolic process 25 1.087111
GO:0050886 endocrine process 27 1.444577
GO:0035601 protein deacylation 27 1.391401
GO:0001569 patterning of blood vessels 27 1.283919
GO:0001823 mesonephros development 19 1.382507
GO:0031103 axon regeneration 14 1.23311
GO:0010869 regulation of receptor biosynthetic process 14 1.210604
GO:0001710 mesodermal cell fate commitment 15 1.096097
GO:0001738 morphogenesis of a polarized epithelium 15 1.0701
GO:0035150 regulation of tube size 50 1.041256
GO:2000278 regulation of DNA biosynthetic process 7 0.99306
GO:0010765 positive regulation of sodium ion transport 7 0.983823
GO:0017148 negative regulation of translation 45 1.249863
GO:0010460 positive regulation of heart rate 14 1.114313
GO:0045620 negative regulation of lymphocyte differentiation 26 0.93453
GO:0046886 positive regulation of hormone biosynthetic process 10 1.297036
GO:0043507 positive regulation of JUN kinase activity 48 1.607977
GO:0006471 protein ADP-ribosylation 19 1.337725
GO:0043473 pigmentation 70 1.202361
GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 9 1.12707
GO:0006878 cellular copper ion homeostasis 9 1.102745
GO:0019319 hexose biosynthetic process 50 0.793979
GO:0021513 spinal cord dorsal/ventral patterning 13 1.544953
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 13 1.519539
GO:0090311 regulation of protein deacetylation 13 1.489449
GO:0007271 synaptic transmission, cholinergic 19 1.304176
GO:0009584 detection of visible light 20 1.256251
GO:0043297 apical junction assembly 32 0.896987
GO:0051240 positive regulation of multicellular organismal process 386 1.555231
GO:0043403 skeletal muscle tissue regeneration 16 1.213355
GO:0001759 organ induction 16 1.207864
GO:0007029 endoplasmic reticulum organization 16 1.199322
GO:0006972 hyperosmotic response 16 1.198576
GO:0045736 negative regulation of cyclin-dependent protein kinase activity 16 1.188379
GO:0033327 Leydig cell differentiation 14 1.103961
GO:0072595 maintenance of protein localization to organelle 26 0.863234
GO:0051865 protein autoubiquitination 26 0.857117
GO:0060675 ureteric bud morphogenesis 46 1.301969
GO:0030539 male genitalia development 21 1.287092
GO:0006929 substrate-dependent cell migration 14 1.095025
GO:0050995 negative regulation of lipid catabolic process 14 1.081701
GO:0035810 positive regulation of urine volume 9 1.061166
GO:0007494 midgut development 14 1.021645
GO:0055081 anion homeostasis 14 1.005096
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 14 0.972444
GO:0085020 protein K6-linked ubiquitination 7 0.970474
GO:0060292 long term synaptic depression 7 0.968836
GO:0060685 regulation of prostatic bud formation 6 1.796287
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 6 1.774045
GO:0001554 luteolysis 6 1.736143
GO:0014060 regulation of epinephrine secretion 6 1.731889
GO:0060684 epithelial-mesenchymal cell signaling 6 1.661577
GO:0014896 muscle hypertrophy 6 1.639176
GO:0051488 activation of anaphase-promoting complex activity 6 1.638933
GO:0060572 morphogenesis of an epithelial bud 6 1.53008
GO:0001821 histamine secretion 6 1.507048
GO:0044344 cellular response to fibroblast growth factor stimulus 6 1.462252
GO:0071774 response to fibroblast growth factor stimulus 6 1.462252
GO:0007614 short-term memory 6 1.455567
GO:0006538 glutamate catabolic process 6 1.437015
GO:0060073 micturition 6 1.416325
GO:0090075 relaxation of muscle 6 1.39894
GO:0008629 induction of apoptosis by intracellular signals 82 1.032547
GO:0022618 ribonucleoprotein complex assembly 94 1.629601
GO:0060644 mammary gland epithelial cell differentiation 11 1.480785
GO:0001553 luteinization 11 1.459141
GO:0030916 otic vesicle formation 11 1.458444
GO:0071600 otic vesicle morphogenesis 11 1.458444
GO:0006461 protein complex assembly 489 1.368032
GO:0002028 regulation of sodium ion transport 24 1.333136
GO:0007565 female pregnancy 138 1.280516
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 44 1.195676
GO:0051282 regulation of sequestering of calcium ion 20 1.182831
GO:0006898 receptor-mediated endocytosis 67 1.124335
GO:0034453 microtubule anchoring 20 1.103204
GO:0010613 positive regulation of cardiac muscle hypertrophy 5 1.053056
GO:0014742 positive regulation of muscle hypertrophy 5 1.053056