ASD

GO:0031330 negative regulation of cellular catabolic process (33)

GeneInput weightStandardRank
CNR10.25129
HDAC4--696
AKT10.2511020
BAG6--1305
N4BP1--1749
KIAA0226--3048
USP44--3406
DDIT4--3443
HSP90AB1--3924
GSK3A--4141
PPARA--4177
FURIN--4605
PTPN3--4627
ADRA1B0.2514946
CST3--15894
HTR2B--6992
TIMP1--8520
DAP--8832
PABPC1--9200
IL10--19513
GIPC1--9877
CLN3--110442
TAF9--10627
MAD2L2--13802
HP--17916
SHH--118571
APOC3--20262
MTOR--21095
INS--122047
APOC1--23668
UBXN1--23735
TIMP3--23921
MAD2L1--25321

Network

GO:0031330

Network
Enrichment
NameDescriptionExternal IDs
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
HDAC4histone deacetylase 4 Entrez:9759  Ensembl: ENSG00000068024  HPRD: 05610  HGNC: 14063 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
BAG6BCL2-associated athanogene 6 Entrez:7917  HGNC: 13919  HPRD: 00808  Ensembl: ENSG00000204463 
N4BP1NEDD4 binding protein 1 Entrez:9683  HGNC: 29850  HPRD: 08109  Ensembl: ENSG00000102921 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CNR1cannabinoid receptor 1 (brain)
HDAC4histone deacetylase 4
AKT1v-akt murine thymoma viral oncogene homolog 1
BAG6BCL2-associated athanogene 6
N4BP1NEDD4 binding protein 1
Query geneGeneGene descriptionEdge score
CNR1CNR1cannabinoid receptor 1 (brain)
HDAC4HDAC4histone deacetylase 4
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
BAG6BAG6BCL2-associated athanogene 6
N4BP1N4BP1NEDD4 binding protein 1

Troyanskaya Laboratory - Princeton University