ASD

GO:0045880 positive regulation of smoothened signaling pathway (17)

GeneInput weightStandardRank
FGF9--262
SFRP1--387
PRRX1--2125
SHOX2--2767
POR0.2515184
GLI1--6241
GAS1--6937
IHH--17160
GPC3--18430
CTNNA1--9331
KIF7--19825
SMO0.25110504
WNT9A--13365
SHH--118571
STK36--21217
DISP1--22983
PRRX2--23936

Network

GO:0045880

Network
Enrichment
NameDescriptionExternal IDs
FGF9fibroblast growth factor 9 Entrez:2254  HPRD: 02951  HGNC: 3687  Ensembl: ENSG00000102678 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
PRRX1paired related homeobox 1 Entrez:5396  HPRD: 01337  HGNC: 9142  Ensembl: ENSG00000116132 
SHOX2short stature homeobox 2 Entrez:6474  HGNC: 10854 
PORP450 (cytochrome) oxidoreductase Entrez:5447  HGNC: 9208  Ensembl: ENSG00000127948  HPRD: 00485 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FGF9fibroblast growth factor 9
SFRP1secreted frizzled-related protein 1
PRRX1paired related homeobox 1
SHOX2short stature homeobox 2
PORP450 (cytochrome) oxidoreductase
Query geneGeneGene descriptionEdge score
FGF9FGF9fibroblast growth factor 9
SFRP1SFRP1secreted frizzled-related protein 1
PRRX1PRRX1paired related homeobox 1
SHOX2SHOX2short stature homeobox 2
PORPORP450 (cytochrome) oxidoreductase

Troyanskaya Laboratory - Princeton University