ASD

GO:0014033 neural crest cell differentiation (49)

GeneInput weightStandardRank
SOX11--96
LRP6--279
SFRP1--387
RET--1524
NRG10.251936
SOX9--1970
HIF1A--1075
EDN3--11577
ISL1--1974
EDNRB--12042
NRP20.2512603
CYP26A1--3009
FOXD3--3025
KITLG--3334
ALDH1A2--3771
EDNRA--13857
GBX2--4440
SOX8--4609
GDNF--14658
HAND2--5589
CYP26C1--5830
HES10.2515912
ACVR1--16054
FOXD2--6176
ZEB2--6361
EFNB1--16517
HTR2B--6992
LAMA5--7171
WNT8A--7814
FOXD4L1--7836
FOXD1--7884
FRZB--8105
SEMA3C--8577
WNT10A--8604
RDH10--9300
EDN1--9540
FOXD4L4--9599
FOXC2--10175
SMO0.25110504
FOXD4--11635
FGF19--12130
FOXC1--113793
FOXD4L5--13951
NRTN--14223
FOXD4L2--16505
SHH--118571
FOXD4L6--19555
FOXS1--20143
SNAI2--123962

Network

GO:0014033

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
RETret proto-oncogene Entrez:5979  HGNC: 9967  Ensembl: ENSG00000165731  HPRD: 01266 
NRG1neuregulin 1 Entrez:3084  HPRD: 00802  Ensembl: ENSG00000157168  HGNC: 7997 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
LRP6low density lipoprotein receptor-related protein 6
SFRP1secreted frizzled-related protein 1
RETret proto-oncogene
NRG1neuregulin 1
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
LRP6LRP6low density lipoprotein receptor-related protein 6
SFRP1SFRP1secreted frizzled-related protein 1
RETRETret proto-oncogene
NRG1NRG1neuregulin 1

Troyanskaya Laboratory - Princeton University