ASD

GO:0009895 negative regulation of catabolic process (56)

GeneInput weightStandardRank
CNR10.25129
GRIN2A0.25166
HDAC4--696
SMAD4--821
SMAD3--823
FYN--932
ADORA1--960
AKT10.2511020
RELA--1142
BAG6--1305
ADRA2A0.2511399
PRKCG--11483
N4BP1--1749
AGAP2--2378
KIAA0226--3048
USP44--3406
DDIT4--3443
SERPINE2--3708
PDE3B--3819
HSP90AB1--3924
GSK3A--4141
PPARA--4177
FLNA--14285
FURIN--4605
PTPN3--4627
ADRA1B0.2514946
GRIN2C--5801
CST3--15894
CIDEA--6211
HTR2B--6992
SERPINB12--7487
MDM4--7770
TIMP1--8520
DAP--8832
PABPC1--9200
IL10--19513
GIPC1--9877
HCAR2--10053
CLN3--110442
TAF9--10627
GIMAP5--10690
IL1B--110818
NOS20.25111577
MAD2L2--13802
IRAK3--14633
APOA2--14659
TNF0.25115243
HP--17916
SHH--118571
APOC3--20262
MTOR--21095
INS--122047
APOC1--23668
UBXN1--23735
TIMP3--23921
MAD2L1--25321

Network

GO:0009895

Network
Enrichment
NameDescriptionExternal IDs
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
HDAC4histone deacetylase 4 Entrez:9759  Ensembl: ENSG00000068024  HPRD: 05610  HGNC: 14063 
SMAD4SMAD family member 4 Entrez:4089  Ensembl: ENSG00000141646  HGNC: 6770  HPRD: 02995 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CNR1cannabinoid receptor 1 (brain)
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
HDAC4histone deacetylase 4
SMAD4SMAD family member 4
SMAD3SMAD family member 3
Query geneGeneGene descriptionEdge score
CNR1CNR1cannabinoid receptor 1 (brain)
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
HDAC4HDAC4histone deacetylase 4
SMAD4SMAD4SMAD family member 4
SMAD3SMAD3SMAD family member 3

Troyanskaya Laboratory - Princeton University