ASD

GO:0007128 meiotic prophase I (19)

GeneInput weightStandardRank
EIF4G3--1083
EHMT2--3182
DMC1--3429
MAEL--4472
PIWIL2--4828
SPO11--4851
DDX4--4901
SYCP2--5994
SYCE1--6366
PRDM9--6886
INSL6--7115
SYCE2--7359
RAD21L1--7470
HORMAD1--9077
FKBP6--9144
WEE2--12601
RAD1--22725
MLH1--125513
TRIP13--25818

Network

GO:0007128

Network
Enrichment
NameDescriptionExternal IDs
EIF4G3eukaryotic translation initiation factor 4 gamma, 3 Entrez:8672  Ensembl: ENSG00000075151  HGNC: 3298  HPRD: 06802 
EHMT2euchromatic histone-lysine N-methyltransferase 2 Entrez:10919  HPRD: 06854  Ensembl: ENSG00000204371  HGNC: 14129 
DMC1DNA meiotic recombinase 1 Entrez:11144  HPRD: 04099  HGNC: 2927  Ensembl: ENSG00000100206 
MAELmaelstrom spermatogenic transposon silencer Entrez:84944  HGNC: 25929  Ensembl: ENSG00000143194  HPRD: 08609 
PIWIL2piwi-like RNA-mediated gene silencing 2 Entrez:55124  HGNC: 17644  HPRD: 11434  Ensembl: ENSG00000197181 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
EIF4G3eukaryotic translation initiation factor 4 gamma, 3
EHMT2euchromatic histone-lysine N-methyltransferase 2
DMC1DNA meiotic recombinase 1
MAELmaelstrom spermatogenic transposon silencer
PIWIL2piwi-like RNA-mediated gene silencing 2
Query geneGeneGene descriptionEdge score
EIF4G3EIF4G3eukaryotic translation initiation factor 4 gamma, 3
EHMT2EHMT2euchromatic histone-lysine N-methyltransferase 2
DMC1DMC1DNA meiotic recombinase 1
MAELMAELmaelstrom spermatogenic transposon silencer
PIWIL2PIWIL2piwi-like RNA-mediated gene silencing 2

Troyanskaya Laboratory - Princeton University