ASD

GO:0009187 cyclic nucleotide metabolic process (48)

GeneInput weightStandardRank
ATP2B20.513
HTR2C0.25162
ADCY2--175
PDE8B--1287
PDE4D--348
ADCY10.251466
GUCY1B3--873
GNAL--1177
PDE4A--1260
GNAS--11842
ADCY9--1850
PDE2A--1938
PTHLH--11993
GUCY1A3--1997
GUCY1A2--2093
PDE4B--2178
PDE1B--2534
PDE11A--2780
ADCY8--2785
ADCY6--2877
PDE4C--3021
ADCY10--3117
RORA--3270
PDE3A--3628
PDE3B--3819
ADCY5--4295
GUCY2F--5264
NUDT4--5300
PDE5A--5684
ADCY3--5755
PTH--6947
HTR2B--6992
NPR2--17127
NPPB--7334
PDE8A--7403
GUCY2D--17484
ADORA2A0.2518408
ADCY4--9091
NPPA--19231
NPPC--9349
GUCA2B--10165
GUCY2C--10523
UCN2--11559
CNP--20759
ADM--21106
AQP1--22433
NPR1--24948
ADCY7--25408

Network

GO:0009187

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Entrez:3358  HGNC: 5295  HPRD: 02429  Ensembl: ENSG00000147246 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
PDE8Bphosphodiesterase 8B Entrez:8622  HGNC: 8794  Ensembl: ENSG00000113231  HPRD: 04546 
PDE4Dphosphodiesterase 4D, cAMP-specific Entrez:5144  HPRD: 02530  HGNC: 8783  Ensembl: ENSG00000113448 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ADCY2adenylate cyclase 2 (brain)
PDE8Bphosphodiesterase 8B
PDE4Dphosphodiesterase 4D, cAMP-specific
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
HTR2CHTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ADCY2ADCY2adenylate cyclase 2 (brain)
PDE8BPDE8Bphosphodiesterase 8B
PDE4DPDE4Dphosphodiesterase 4D, cAMP-specific

Troyanskaya Laboratory - Princeton University