ASD

GO:0030804 positive regulation of cyclic nucleotide biosynthetic process (34)

GeneInput weightStandardRank
ADNP1.0171
DRD10.251899
ADRB1--1057
DRD50.2511103
ADCYAP1R1--1273
AKAP5--1759
SPECC1L--1912
PTHLH--11993
GUCY1A3--1997
MC2R--3795
AKAP12--3839
MC4R0.2513850
GSK3A--4141
GHRHR--4237
ABCA1--14703
MC5R--4977
GCG--5190
MRAP2--5265
RXFP2--15887
PTH--6947
GHRH--7478
MC1R--17999
MC3R0.2518188
ADORA2A0.2518408
NPPC--9349
GIPR--10369
MRAP--10905
AVP--113439
INSL3--119059
ADORA2B--19522
GPR65--22555
APOE0.25123516
NPR1--24948
ADCY7--25408

Network

GO:0030804

Network
Enrichment
NameDescriptionExternal IDs
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  Ensembl: ENSG00000101126  HPRD: 09793  HGNC: 15766 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
ADRB1adrenoceptor beta 1 Entrez:153  HGNC: 285  Ensembl: ENSG00000043591  HPRD: 00181 
DRD5dopamine receptor D5 Entrez:1816  HGNC: 3026  Ensembl: ENSG00000169676  HPRD: 00542 
ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I Entrez:117  HGNC: 242  Ensembl: ENSG00000078549  HPRD: 00045 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ADNPactivity-dependent neuroprotector homeobox
DRD1dopamine receptor D1
ADRB1adrenoceptor beta 1
DRD5dopamine receptor D5
ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
Query geneGeneGene descriptionEdge score
ADNPADNPactivity-dependent neuroprotector homeobox
DRD1DRD1dopamine receptor D1
ADRB1ADRB1adrenoceptor beta 1
DRD5DRD5dopamine receptor D5
ADCYAP1R1ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I

Troyanskaya Laboratory - Princeton University