ASD

GO:0032320 positive regulation of Ras GTPase activity (84)

GeneInput weightStandardRank
RASGRF1--335
NF10.251372
SFRP1--387
GSK3B--427
ARHGAP5--464
JUN--511
RAPGEF2--540
SIPA1L1--716
TSC10.251790
SOS1--1810
RABGAP1L--846
MAP2K10.251907
ARHGAP35--908
NDEL10.2511074
DLC1--1282
RALGAPA1--1420
THY1--1580
DOCK40.2511765
RASAL2--1889
TBC1D10B--1952
RASA1--1983
PREX1--2760
FZD10--2957
PTK2B--3063
PREX2--3163
ARHGAP1--3304
DAB2IP--3482
CDKL5--13600
RASAL1--3614
ARHGAP26--13662
SYNGAP11.014039
S1PR1--4301
ARHGAP29--4559
ARAP3--4767
RALGAPA2--4803
RASA2--4877
MYO9B0.515005
RANGAP1--5328
ARHGAP6--5374
RHOG--6279
ALS2--16326
OPHN10.516584
RALBP1--6643
ERRFI1--6649
HTR2B--6992
GRHL3--7409
SYDE2--7604
FOXJ1--7628
WNT11--7820
PIN1--7940
CXCL13--8148
RASGRP3--8406
RASA4--8961
RAB3GAP1--9492
CCL11--9615
SYDE1--9690
TBC1D15--10227
ARHGAP8--11916
ARHGEF19--14560
CCL19--14578
TAX1BP3--15553
RASA3--15787
ARHGEF10L--17881
EPHA2--119467
ALDH1A1--19488
CDC42EP2--19500
DOCK7--19597
RASAL3--19660
ARHGAP15--21045
ARHGEF16--21200
SIPA1--21260
ARHGAP4--21362
CCL21--21829
CCL24--21868
RALGAPB--22093
GMIP--22274
CCR7--22367
GPR65--22555
CCL26--22814
SCRIB--23676
TBC1D2--23738
NCKAP1L--23771
ARHGAP27--23975
ARAP1--24899

Network

GO:0032320

Network
Enrichment
NameDescriptionExternal IDs
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1 Entrez:5923  HGNC: 9875  Ensembl: ENSG00000058335 
NF1neurofibromin 1 Entrez:4763  HGNC: 7765  HPRD: 01203  Ensembl: ENSG00000196712 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
GSK3Bglycogen synthase kinase 3 beta Entrez:2932  Ensembl: ENSG00000082701  HPRD: 05418  HGNC: 4617 
ARHGAP5Rho GTPase activating protein 5 Entrez:394  HPRD: 04060  HGNC: 675  Ensembl: ENSG00000100852 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
NF1neurofibromin 1
SFRP1secreted frizzled-related protein 1
GSK3Bglycogen synthase kinase 3 beta
ARHGAP5Rho GTPase activating protein 5
Query geneGeneGene descriptionEdge score
RASGRF1RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
NF1NF1neurofibromin 1
SFRP1SFRP1secreted frizzled-related protein 1
GSK3BGSK3Bglycogen synthase kinase 3 beta
ARHGAP5ARHGAP5Rho GTPase activating protein 5

Troyanskaya Laboratory - Princeton University