ASD

GO:0019722 calcium-mediated signaling (41)

GeneInput weightStandardRank
HDAC4--696
DRD10.251899
RYR2--1959
GRM10.251975
CAMKK2--1053
RCAN2--1540
FKBP1B--2346
EGFR--12546
CASQ1--2959
AVPR1A0.513803
MCTP1--4524
GPR143--14685
NUDT4--5300
AGTR1--16275
NMUR2--6430
PLCE1--6929
HTR2B--6992
CASR--7200
GPRC6A--7662
LACRT--7733
KISS1R--9434
EDN1--9540
BHLHA15--9905
MCTP2--10728
PTGDR2--10914
TREML1--11807
SELE--14642
TNF0.25115243
IL8--15864
EDN2--18677
RCAN1--18854
NMUR1--19043
RCAN3--19521
EIF2AK3--20456
P2RY11--20669
LAT--20987
BTK--122251
PLA2G4B--22374
MCU--22796
SPHK1--24069
LAT2--24455

Network

GO:0019722

Network
Enrichment
NameDescriptionExternal IDs
HDAC4histone deacetylase 4 Entrez:9759  Ensembl: ENSG00000068024  HPRD: 05610  HGNC: 14063 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
RYR2ryanodine receptor 2 (cardiac) Entrez:6262  Ensembl: ENSG00000198626  HGNC: 10484  HPRD: 01619 
GRM1glutamate receptor, metabotropic 1 Entrez:2911  HGNC: 4593  Ensembl: ENSG00000152822  HPRD: 05129 
CAMKK2calcium/calmodulin-dependent protein kinase kinase 2, beta Entrez:10645  Ensembl: ENSG00000110931  HPRD: 06467  HGNC: 1470 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
HDAC4histone deacetylase 4
DRD1dopamine receptor D1
RYR2ryanodine receptor 2 (cardiac)
GRM1glutamate receptor, metabotropic 1
CAMKK2calcium/calmodulin-dependent protein kinase kinase 2, beta
Query geneGeneGene descriptionEdge score
HDAC4HDAC4histone deacetylase 4
DRD1DRD1dopamine receptor D1
RYR2RYR2ryanodine receptor 2 (cardiac)
GRM1GRM1glutamate receptor, metabotropic 1
CAMKK2CAMKK2calcium/calmodulin-dependent protein kinase kinase 2, beta

Troyanskaya Laboratory - Princeton University