ASD

GO:0071634 regulation of transforming growth factor-beta production (16)

GeneInput weightStandardRank
CREB1--100
SMAD4--821
SMAD3--823
TGFB2--834
HIF1A--1075
ATF2--1309
FURIN--4605
PTGS20.2515085
XCL1--7819
WNT11--7820
CD24--18102
GATA6--110828
FOXP3--112457
IL13--12888
THBS1--24444
ATP6AP2--25361

Network

GO:0071634

Network
Enrichment
NameDescriptionExternal IDs
CREB1cAMP responsive element binding protein 1 Entrez:1385  HGNC: 2345  HPRD: 00442  Ensembl: ENSG00000118260 
SMAD4SMAD family member 4 Entrez:4089  Ensembl: ENSG00000141646  HGNC: 6770  HPRD: 02995 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CREB1cAMP responsive element binding protein 1
SMAD4SMAD family member 4
SMAD3SMAD family member 3
TGFB2transforming growth factor, beta 2
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Query geneGeneGene descriptionEdge score
CREB1CREB1cAMP responsive element binding protein 1
SMAD4SMAD4SMAD family member 4
SMAD3SMAD3SMAD family member 3
TGFB2TGFB2transforming growth factor, beta 2
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

Troyanskaya Laboratory - Princeton University