ASD

GO:0060627 regulation of vesicle-mediated transport (150)

GeneInput weightStandardRank
SYT1--11
VAMP2--33
PLCB1--148
CADPS--133
SYNJ1--156
ABR--160
AMPH--169
AP2S1--210
CACNA1A--1270
SH3GL2--454
NEDD4L--495
STX1A0.251512
SNAP91--546
PFN2--551
BICD1--552
CRHR1--589
SNCA--1667
CLIP3--730
STXBP1--769
IL1RAPL10.251774
RAB3A0.251848
HNRNPK--885
RAPGEF40.251904
MIB10.2511153
EPN2--1277
DOC2A0.2511359
ADRA2A0.2511399
CBL--1478
SYT7--1536
RAC1--1617
SGIP1--1665
CDH13--1692
USP6--1693
HIP1--1797
TUB0.2511820
BCR--11839
RAB3B--1982
SEPT5--2143
CALY--2456
RAB26--2496
CD47--2580
PICALM--12597
NCS1--2628
SCAMP50.2512682
ACTN4--12685
NOTCH1--12865
GLRA1--2965
KIAA0226--3048
CDK50.2513194
GATA2--13291
ARF6--3317
RAB5C--3377
GAB2--3496
FOXF1--13518
SLC30A8--13644
STXBP5--3733
DRD20.2513749
CACNA1H1.013855
ITGB1--3903
STX1B--3973
RALA--4169
ANGPT1--4182
RAB3C--4397
PACSIN1--4607
LGI3--4664
WNT3A--4747
SYT9--5512
ZFYVE16--5592
STON2--5811
RALB--5931
ADIPOQ0.2516032
STON1--6168
NR1H2--6183
BIN1--6197
NAPB--6293
PTX3--6392
CNST--6559
OPHN10.516584
GOPC--6764
SCYL2--7130
RSPO1--7229
SFRP4--7310
TRPV6--7927
RPH3AL--8235
GPC3--18430
SNX17--8597
SFTPD--8649
MBL2--8801
STXBP2--18948
TSC20.2519351
NSF--9493
REST--9779
PKDCC--9871
TULP1--110015
PCSK9--10760
DOC2B--11084
AHSG--11515
DKK1--11567
RAB27B--12713
LRSAM1--13116
MS4A2--13136
FGF2--13150
MTMR2--113176
VTN--13271
SCARB1--13530
APOC2--13818
APOA5--113831
PPT1--113834
SPACA3--14401
RSG1--14486
CCL19--14578
SELE--14642
ZP4--14747
SCFD1--16551
ZP3--17443
AZU1--18895
CBLL1--19963
F2RL1--19969
TGFB10.25120135
APOC3--20262
ANXA2--20584
PACSIN3--21093
RAB4A--21142
UNC13D--121158
RAB3D--21252
FCER1G--21507
NOD2--121514
CCL21--21829
CALR--22152
B4GALT1--122700
PLA2G4A--22727
ANXA10.5122810
PLD2--22908
GNB2L1--23282
CCR2--23296
EHD4--23403
SLC11A1--23561
CD36--23662
APOC1--23668
NCKAP1L--23771
SYK--23906
HMOX1--23938
NR1H3--25006
SERPINE10.25125055
CNN2--25083
STXBP3--25176
LDLRAP1--25289
C3--125347
CAV1--125381
ITGAV--25460

Network

GO:0060627

Network
Enrichment
NameDescriptionExternal IDs
SYT1synaptotagmin I Entrez:6857  HPRD: 01710  HGNC: 11509  Ensembl: ENSG00000067715 
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2) Entrez:6844  HGNC: 12643  HPRD: 01717  Ensembl: ENSG00000220205 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
CADPSCa++-dependent secretion activator Entrez:8618  Ensembl: ENSG00000163618  HGNC: 1426  HPRD: 05236 
SYNJ1synaptojanin 1 Entrez:8867  Ensembl: ENSG00000159082  HGNC: 11503  HPRD: 09182 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYT1synaptotagmin I
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCa++-dependent secretion activator
SYNJ1synaptojanin 1
Query geneGeneGene descriptionEdge score
SYT1SYT1synaptotagmin I
VAMP2VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCADPSCa++-dependent secretion activator
SYNJ1SYNJ1synaptojanin 1

Troyanskaya Laboratory - Princeton University