ASD

GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway (34)

GeneInput weightStandardRank
NR3C1--496
PEG10--627
SMAD7--1192
ONECUT2--1700
STRAP--1732
LEMD3--12084
FBN2--2131
SMAD6--2305
BCL9L--2729
SKIL--2889
SKI--2904
SMURF1--3060
NKX2-1--4142
GLG1--4233
PRDM16--4345
WNT1--4383
ADAMTSL2--6151
CIDEA--6211
TGFBR3--6672
PIN1--7940
BAMBI--8550
CHST11--9003
FBN1--110976
ASPN--11718
DAND5--12647
SKOR2--12780
SKOR1--12870
TGFB3--113097
HSPA5--19143
EID2--21599
SNX6--22713
TGFB1I1--23709
LTBP1--24489
ENG--124746

Network

GO:0030512

Network
Enrichment
NameDescriptionExternal IDs
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
PEG10paternally expressed 10 Entrez:23089  Ensembl: ENSG00000242265  HGNC: 14005 
SMAD7SMAD family member 7 Entrez:4092  HPRD: 04241  HGNC: 6773  Ensembl: ENSG00000101665 
ONECUT2one cut homeobox 2 Entrez:9480  HGNC: 8139  Ensembl: ENSG00000119547  HPRD: 05354 
STRAPserine/threonine kinase receptor associated protein Entrez:11171  HGNC: 30796  HPRD: 05816  Ensembl: ENSG00000023734 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PEG10paternally expressed 10
SMAD7SMAD family member 7
ONECUT2one cut homeobox 2
STRAPserine/threonine kinase receptor associated protein
Query geneGeneGene descriptionEdge score
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PEG10PEG10paternally expressed 10
SMAD7SMAD7SMAD family member 7
ONECUT2ONECUT2one cut homeobox 2
STRAPSTRAPserine/threonine kinase receptor associated protein

Troyanskaya Laboratory - Princeton University