ASD

GO:0050931 pigment cell differentiation (25)

GeneInput weightStandardRank
OCA2--11297
SOX10--11520
EDN3--11577
EDNRB--12042
TYRP1--12801
FOXD3--3025
CITED1--3064
FOXD2--6176
GLI3--16261
MITF--16345
FOXD4L1--7836
FOXD1--7884
FOXD4L4--9599
FOXD4--11635
HPS4--12942
MLPH0.25113326
MREG--13587
FOXD4L5--13951
FOXD4L2--16505
FOXD4L6--19555
BLOC1S6--21368
HPS6--22247
SOD2--22687
RAB27A--24284
HPS1--124327

Network

GO:0050931

Network
Enrichment
NameDescriptionExternal IDs
OCA2oculocutaneous albinism II Entrez:4948  Ensembl: ENSG00000104044  HPRD: 01945  HGNC: 8101 
SOX10SRY (sex determining region Y)-box 10 Entrez:6663  Ensembl: ENSG00000100146  HGNC: 11190  HPRD: 03752 
EDN3endothelin 3 Entrez:1908  HGNC: 3178  Ensembl: ENSG00000124205  HPRD: 00570 
EDNRBendothelin receptor type B Entrez:1910  Ensembl: ENSG00000136160  HPRD: 08834  HGNC: 3180 
TYRP1tyrosinase-related protein 1 Entrez:7306  Ensembl: ENSG00000107165  HGNC: 12450  HPRD: 00283 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
OCA2oculocutaneous albinism II
SOX10SRY (sex determining region Y)-box 10
EDN3endothelin 3
EDNRBendothelin receptor type B
TYRP1tyrosinase-related protein 1
Query geneGeneGene descriptionEdge score
OCA2OCA2oculocutaneous albinism II
SOX10SOX10SRY (sex determining region Y)-box 10
EDN3EDN3endothelin 3
EDNRBEDNRBendothelin receptor type B
TYRP1TYRP1tyrosinase-related protein 1

Troyanskaya Laboratory - Princeton University