ASD

GO:0001755 neural crest cell migration (29)

GeneInput weightStandardRank
RET--1524
HIF1A--1075
EDN3--11577
ISL1--1974
EDNRB--12042
NRP20.2512603
FOXD3--3025
KITLG--3334
GBX2--4440
SOX8--4609
GDNF--14658
ACVR1--16054
FOXD2--6176
ZEB2--6361
EFNB1--16517
HTR2B--6992
LAMA5--7171
FOXD4L1--7836
FOXD1--7884
SEMA3C--8577
FOXD4L4--9599
SMO0.25110504
FOXD4--11635
FGF19--12130
FOXD4L5--13951
NRTN--14223
FOXD4L2--16505
SHH--118571
FOXD4L6--19555

Network

GO:0001755

Network
Enrichment
NameDescriptionExternal IDs
RETret proto-oncogene Entrez:5979  HGNC: 9967  Ensembl: ENSG00000165731  HPRD: 01266 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
EDN3endothelin 3 Entrez:1908  HGNC: 3178  Ensembl: ENSG00000124205  HPRD: 00570 
ISL1ISL LIM homeobox 1 Entrez:3670  HGNC: 6132  Ensembl: ENSG00000016082  HPRD: 02650 
EDNRBendothelin receptor type B Entrez:1910  Ensembl: ENSG00000136160  HPRD: 08834  HGNC: 3180 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RETret proto-oncogene
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
EDN3endothelin 3
ISL1ISL LIM homeobox 1
EDNRBendothelin receptor type B
Query geneGeneGene descriptionEdge score
RETRETret proto-oncogene
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
EDN3EDN3endothelin 3
ISL1ISL1ISL LIM homeobox 1
EDNRBEDNRBendothelin receptor type B

Troyanskaya Laboratory - Princeton University