ASD

GO:0017158 regulation of calcium ion-dependent exocytosis (22)

GeneInput weightStandardRank
SYT1--11
PLCB1--148
CADPS--133
CACNA1A--1270
DOC2A0.2511359
ADRA2A0.2511399
SYT7--1536
SCAMP50.2512682
NOTCH1--12865
GLRA1--2965
CDK50.2513194
CACNA1H1.013855
SYT9--5512
TRPV6--7927
RPH3AL--8235
REST--9779
DOC2B--11084
FGF2--13150
ZP4--14747
ZP3--17443
B4GALT1--122700
STXBP3--25176

Network

GO:0017158

Network
Enrichment
NameDescriptionExternal IDs
SYT1synaptotagmin I Entrez:6857  HPRD: 01710  HGNC: 11509  Ensembl: ENSG00000067715 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
CADPSCa++-dependent secretion activator Entrez:8618  Ensembl: ENSG00000163618  HGNC: 1426  HPRD: 05236 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
DOC2Adouble C2-like domains, alpha Entrez:8448  Ensembl: ENSG00000149927  HPRD: 05195  HGNC: 2985 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYT1synaptotagmin I
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCa++-dependent secretion activator
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
DOC2Adouble C2-like domains, alpha
Query geneGeneGene descriptionEdge score
SYT1SYT1synaptotagmin I
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCADPSCa++-dependent secretion activator
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
DOC2ADOC2Adouble C2-like domains, alpha

Troyanskaya Laboratory - Princeton University