ASD

GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway (8)

GeneInput weightStandardRank
GNAQ--189
DRD10.251899
DRD50.2511103
GNA11--2281
GNA14--3634
DRD20.2513749
GNA15--20926
SLC9A3R1--21898

Network

GO:0060158

Network
Enrichment
NameDescriptionExternal IDs
GNAQguanine nucleotide binding protein (G protein), q polypeptide Entrez:2776  HGNC: 4390  HPRD: 02998 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
DRD5dopamine receptor D5 Entrez:1816  HGNC: 3026  Ensembl: ENSG00000169676  HPRD: 00542 
GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class) Entrez:2767  HGNC: 4379  HPRD: 00759 
GNA14guanine nucleotide binding protein (G protein), alpha 14 Entrez:9630  HGNC: 4382  HPRD: 05095  Ensembl: ENSG00000156049 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAQguanine nucleotide binding protein (G protein), q polypeptide
DRD1dopamine receptor D1
DRD5dopamine receptor D5
GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA14guanine nucleotide binding protein (G protein), alpha 14
Query geneGeneGene descriptionEdge score
GNAQGNAQguanine nucleotide binding protein (G protein), q polypeptide
DRD1DRD1dopamine receptor D1
DRD5DRD5dopamine receptor D5
GNA11GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA14GNA14guanine nucleotide binding protein (G protein), alpha 14

Troyanskaya Laboratory - Princeton University