ASD

GO:0014066 regulation of phosphatidylinositol 3-kinase cascade (31)

GeneInput weightStandardRank
UBE3A0.251365
TGFB2--834
SOX9--1970
NCOR1--1019
ERBB3--1350
CBL--1478
IGF10.2512793
KLF4--3609
SERPINE2--3708
PDGFA--3731
WNT16--4117
SLC9A3R2--5711
PPARD--6562
TWIST1--16980
GH1--7858
TSC20.2519351
AGT--113305
NEDD40.25114040
JAK2--119561
F2RL1--19969
F2R--20036
PDGFB--21071
SLC9A3R1--21898
INS--122047
PLD2--22908
CCL5--23042
ENTPD5--23045
ERBB2--123130
PDGFRB--23242
PTPN6--24184
CAT--25268

Network

GO:0014066

Network
Enrichment
NameDescriptionExternal IDs
UBE3Aubiquitin protein ligase E3A Entrez:7337  HPRD: 03375  HGNC: 12496  Ensembl: ENSG00000114062 
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
SOX9SRY (sex determining region Y)-box 9 Entrez:6662  HPRD: 06427  HGNC: 11204  Ensembl: ENSG00000125398 
NCOR1nuclear receptor corepressor 1 Entrez:9611  Ensembl: ENSG00000141027  HPRD: 02911  HGNC: 7672 
ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 Entrez:2065  HGNC: 3431  Ensembl: ENSG00000065361  HPRD: 01820 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
UBE3Aubiquitin protein ligase E3A
TGFB2transforming growth factor, beta 2
SOX9SRY (sex determining region Y)-box 9
NCOR1nuclear receptor corepressor 1
ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Query geneGeneGene descriptionEdge score
UBE3AUBE3Aubiquitin protein ligase E3A
TGFB2TGFB2transforming growth factor, beta 2
SOX9SOX9SRY (sex determining region Y)-box 9
NCOR1NCOR1nuclear receptor corepressor 1
ERBB3ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

Troyanskaya Laboratory - Princeton University