ASD

GO:0046928 regulation of neurotransmitter secretion (28)

GeneInput weightStandardRank
NTRK20.25151
CAMK2A--249
CACNA1A--1270
NF10.251372
STX1A0.251512
PFN2--551
SNCA--1667
STXBP1--769
RAB3A0.251848
PARK20.251952
SNCAIP--1042
CHRNA3--1266
GRM80.2511404
EDN3--11577
KCNMB4--1767
SPECC1L--1912
KCNC3--12203
KCNC4--2573
SNCG--3502
CPLX3--4281
CHRNB4--4903
NGF0.2516229
NAPB--6293
DRD40.2517021
SLC30A1--7241
ADORA2A0.2518408
CPLX4--10481
HCRT0.25111633

Network

GO:0046928

Network
Enrichment
NameDescriptionExternal IDs
NTRK2neurotrophic tyrosine kinase, receptor, type 2 Entrez:4915  Ensembl: ENSG00000148053  HPRD: 02712  HGNC: 8032 
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha Entrez:815  HGNC: 1460  HPRD: 06532  Ensembl: ENSG00000070808 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
NF1neurofibromin 1 Entrez:4763  HGNC: 7765  HPRD: 01203  Ensembl: ENSG00000196712 
STX1Asyntaxin 1A (brain) Entrez:6804  Ensembl: ENSG00000106089  HGNC: 11433  HPRD: 01721 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK2neurotrophic tyrosine kinase, receptor, type 2
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
NF1neurofibromin 1
STX1Asyntaxin 1A (brain)
Query geneGeneGene descriptionEdge score
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2
CAMK2ACAMK2Acalcium/calmodulin-dependent protein kinase II alpha
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
NF1NF1neurofibromin 1
STX1ASTX1Asyntaxin 1A (brain)

Troyanskaya Laboratory - Princeton University