ASD

GO:0045740 positive regulation of DNA replication (42)

GeneInput weightStandardRank
IGF1R--252
PDGFRA--1320
JUN--511
CDC42--1138
TNKS--1414
CIZ1--2164
IGF10.2512793
KITLG--3334
PDGFA--3731
MAS1--4244
IL3--4316
TNKS2--4385
FGF10--14532
HRAS0.2515086
INSR--15872
CST3--15894
PLA2G1B--6059
GLI1--6241
PDGFC--6530
GLI2--17307
MET1.018002
AREG--8583
EREG--9052
NPM2--9431
SHC1--10045
UCN--10358
IL6--112695
TGFB3--113097
CSF2--13423
CACYBP--19557
AREGB--19783
EPO--20282
PDGFB--21071
INO80--21496
INS--122047
CALR--22152
CTC1--22384
ATF1--24277
OBFC1--24311
POT1--24483
CDK1--25053
DNA2--25572

Network

GO:0045740

Network
Enrichment
NameDescriptionExternal IDs
IGF1Rinsulin-like growth factor 1 receptor Entrez:3480  Ensembl: ENSG00000140443  HPRD: 00932  HGNC: 5465 
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide Entrez:5156  Ensembl: ENSG00000134853  HPRD: 01429  HGNC: 8803 
JUNjun proto-oncogene Entrez:3725  HGNC: 6204  HPRD: 01302  Ensembl: ENSG00000177606 
CDC42cell division cycle 42 Entrez:998  HPRD: 00309  HGNC: 1736  Ensembl: ENSG00000070831 
TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase Entrez:8658  HGNC: 11941  Ensembl: ENSG00000173273  HPRD: 04490 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
IGF1Rinsulin-like growth factor 1 receptor
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide
JUNjun proto-oncogene
CDC42cell division cycle 42
TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Query geneGeneGene descriptionEdge score
IGF1RIGF1Rinsulin-like growth factor 1 receptor
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptide
JUNJUNjun proto-oncogene
CDC42CDC42cell division cycle 42
TNKSTNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

Troyanskaya Laboratory - Princeton University