ASD

GO:0061311 cell surface receptor linked signaling pathway involved in heart development (8)

GeneInput weightStandardRank
LRP6--279
WNT5A--3319
WNT3A--4747
BMP2--14855
BMP4--16499
CTNNB10.519066
POU5F1--19704
JUP--120291

Network

GO:0061311

Network
Enrichment
NameDescriptionExternal IDs
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
WNT5Awingless-type MMTV integration site family, member 5A Entrez:7474  Ensembl: ENSG00000114251  HPRD: 01293  HGNC: 12784 
WNT3Awingless-type MMTV integration site family, member 3A Entrez:89780  HPRD: 05897  HGNC: 15983  Ensembl: ENSG00000154342 
BMP2bone morphogenetic protein 2 Entrez:650  HGNC: 1069  HPRD: 00206  Ensembl: ENSG00000125845 
BMP4bone morphogenetic protein 4 Entrez:652  Ensembl: ENSG00000125378  HPRD: 00207  HGNC: 1071 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
LRP6low density lipoprotein receptor-related protein 6
WNT5Awingless-type MMTV integration site family, member 5A
WNT3Awingless-type MMTV integration site family, member 3A
BMP2bone morphogenetic protein 2
BMP4bone morphogenetic protein 4
Query geneGeneGene descriptionEdge score
LRP6LRP6low density lipoprotein receptor-related protein 6
WNT5AWNT5Awingless-type MMTV integration site family, member 5A
WNT3AWNT3Awingless-type MMTV integration site family, member 3A
BMP2BMP2bone morphogenetic protein 2
BMP4BMP4bone morphogenetic protein 4

Troyanskaya Laboratory - Princeton University