ASD

GO:0045581 negative regulation of T cell differentiation (21)

GeneInput weightStandardRank
SOCS5--463
RC3H1--2217
BCL6--2550
IFNB1--5250
DTX1--5290
PRDX2--5497
GLI3--16261
BMP4--16499
CTLA4--6866
IHH--17160
TNFSF4--7262
FOXJ1--7628
IFNA2--7694
IFNL1--10151
NFKBID--13229
NRARP--14597
SHH--118571
JAK3--20340
IL4R--20610
CD74--24030
ZC3H8--24341

Network

GO:0045581

Network
Enrichment
NameDescriptionExternal IDs
SOCS5suppressor of cytokine signaling 5 Entrez:9655  HPRD: 06159  HGNC: 16852  Ensembl: ENSG00000171150 
RC3H1ring finger and CCCH-type domains 1 Entrez:149041  Ensembl: ENSG00000135870  HPRD: 13913  HGNC: 29434 
BCL6B-cell CLL/lymphoma 6 Entrez:604  HGNC: 1001  Ensembl: ENSG00000113916  HPRD: 00180 
IFNB1interferon, beta 1, fibroblast Entrez:3456  HPRD: 00972  HGNC: 5434  Ensembl: ENSG00000171855 
DTX1deltex homolog 1 (Drosophila) Entrez:1840  HGNC: 3060  HPRD: 03991  Ensembl: ENSG00000135144 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOCS5suppressor of cytokine signaling 5
RC3H1ring finger and CCCH-type domains 1
BCL6B-cell CLL/lymphoma 6
IFNB1interferon, beta 1, fibroblast
DTX1deltex homolog 1 (Drosophila)
Query geneGeneGene descriptionEdge score
SOCS5SOCS5suppressor of cytokine signaling 5
RC3H1RC3H1ring finger and CCCH-type domains 1
BCL6BCL6B-cell CLL/lymphoma 6
IFNB1IFNB1interferon, beta 1, fibroblast
DTX1DTX1deltex homolog 1 (Drosophila)

Troyanskaya Laboratory - Princeton University