ASD

GO:0061136 regulation of proteasomal protein catabolic process (52)

GeneInput weightStandardRank
PSMD14--104
SUMO1--1411
TRIB2--472
RAD23B--658
CSNK1D--699
CSNK1E0.251752
AKT10.2511020
SMAD7--1192
USP14--1209
BAG6--1305
PTEN1.011389
WNT10B--1517
RCHY1--1615
N4BP1--1749
BTRC--1884
UBE2V2--1939
PSMD10--2412
USP44--3406
TRIB1--3431
HSP90AB1--3924
SUMO2--4064
STUB1--4250
RNF180--4255
PRICKLE1--15552
DNAJB2--6026
MDM2--6675
VCP--7434
LRRK2--18802
HSPBP1--9785
USP5--9852
GIPC1--9877
TAF9--10627
TAF1--10729
GPX10.25111644
RAD23A--11998
GCLC--12360
DYX1C10.25113222
MAD2L2--13802
PSEN1--18523
SHH--118571
NUB1--21779
PSME3--22162
UCHL5--22745
RHBDF1--23088
GNB2L1--23282
FBXO22--23669
UBXN1--23735
COMMD1--24027
MAD2L1--25321
DAB2--25338
CLU--25437
PLK1--25783

Network

GO:0061136

Network
Enrichment
NameDescriptionExternal IDs
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
SUMO1small ubiquitin-like modifier 1 Entrez:7341  Ensembl: ENSG00000116030  HGNC: 12502  HPRD: 03554 
TRIB2tribbles homolog 2 (Drosophila) Entrez:28951  HPRD: 18224  HGNC: 30809  Ensembl: ENSG00000071575 
RAD23BRAD23 homolog B (S. cerevisiae) Entrez:5887  Ensembl: ENSG00000119318  HPRD: 06772  HGNC: 9813 
CSNK1Dcasein kinase 1, delta Entrez:1453  Ensembl: ENSG00000141551  HGNC: 2452  HPRD: 02920 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
SUMO1small ubiquitin-like modifier 1
TRIB2tribbles homolog 2 (Drosophila)
RAD23BRAD23 homolog B (S. cerevisiae)
CSNK1Dcasein kinase 1, delta
Query geneGeneGene descriptionEdge score
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
SUMO1SUMO1small ubiquitin-like modifier 1
TRIB2TRIB2tribbles homolog 2 (Drosophila)
RAD23BRAD23BRAD23 homolog B (S. cerevisiae)
CSNK1DCSNK1Dcasein kinase 1, delta

Troyanskaya Laboratory - Princeton University