ASD

GO:0070169 positive regulation of biomineral tissue development (28)

GeneInput weightStandardRank
BMPR2--1281
SMAD3--823
ACVR2A--965
BMP7--1137
BMPR1A--1140
WNT10B--1517
ACVR2B--11676
FBN2--2131
BMPR1B--12316
TFAP2A--12923
AMELX--13396
KL--3938
BMP6--4358
BMP2--14855
WNT6--5106
OSR1--5691
ACVR1--16054
BMP4--16499
P2RX7--7888
PKDCC--9871
TGFB3--113097
CD276--13688
PPARGC1B--115356
TGFB10.25120135
OSR2--20931
WNT4--21809
PLA2G4A--22727
ADRB20.25123251

Network

GO:0070169

Network
Enrichment
NameDescriptionExternal IDs
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
ACVR2Aactivin A receptor, type IIA Entrez:92  HGNC: 173  HPRD: 00025  Ensembl: ENSG00000121989 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
BMPR1Abone morphogenetic protein receptor, type IA Entrez:657  HGNC: 1076  Ensembl: ENSG00000107779  HPRD: 03192 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
SMAD3SMAD family member 3
ACVR2Aactivin A receptor, type IIA
BMP7bone morphogenetic protein 7
BMPR1Abone morphogenetic protein receptor, type IA
Query geneGeneGene descriptionEdge score
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
SMAD3SMAD3SMAD family member 3
ACVR2AACVR2Aactivin A receptor, type IIA
BMP7BMP7bone morphogenetic protein 7
BMPR1ABMPR1Abone morphogenetic protein receptor, type IA

Troyanskaya Laboratory - Princeton University