GO:0032069 regulation of nuclease activity (8)

GeneInput weightStandardRank
SIRT1--1233
PCNA--2671
HMGB2--3362
NEIL1--9093
ERN1--9939
HSPA5--19143
NPM1--121865
GZMA--21944

Network

GO:0032069

Network
Enrichment
NameDescriptionExternal IDs
SIRT1sirtuin 1 Entrez:23411  Ensembl: ENSG00000096717  HPRD: 08381  HGNC: 14929 
PCNAproliferating cell nuclear antigen Entrez:5111  HPRD: 01456  HGNC: 8729  Ensembl: ENSG00000132646 
HMGB2high mobility group box 2 Entrez:3148  HGNC: 5000  HPRD: 01229 
NEIL1nei endonuclease VIII-like 1 (E. coli) Entrez:79661  HPRD: 12314  HGNC: 18448  Ensembl: ENSG00000140398 
ERN1endoplasmic reticulum to nucleus signaling 1 Entrez:2081  HPRD: 04943  Ensembl: ENSG00000178607  HGNC: 3449 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SIRT1sirtuin 1
PCNAproliferating cell nuclear antigen
HMGB2high mobility group box 2
NEIL1nei endonuclease VIII-like 1 (E. coli)
ERN1endoplasmic reticulum to nucleus signaling 1
Query geneGeneGene descriptionEdge score
SIRT1SIRT1sirtuin 1
PCNAPCNAproliferating cell nuclear antigen
HMGB2HMGB2high mobility group box 2
NEIL1NEIL1nei endonuclease VIII-like 1 (E. coli)
ERN1ERN1endoplasmic reticulum to nucleus signaling 1