ASD

GO:0090201 negative regulation of release of cytochrome c from mitochondria (5)

GeneInput weightStandardRank
PARK20.251952
PSMD10--2412
BCL2L1--6563
AVP--113439
FXN--125604

Network

GO:0090201

Network
Enrichment
NameDescriptionExternal IDs
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin) Entrez:5071  HPRD: 03967  HGNC: 8607  Ensembl: ENSG00000185345 
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 Entrez:5716  HPRD: 04594  HGNC: 9555  Ensembl: ENSG00000101843 
BCL2L1BCL2-like 1 Entrez:598  HGNC: 992  Ensembl: ENSG00000171552  HPRD: 02497 
AVParginine vasopressin Entrez:551  HGNC: 894  HPRD: 01891  Ensembl: ENSG00000101200 
FXNfrataxin Entrez:2395  Ensembl: ENSG00000165060  HPRD: 06013  HGNC: 3951 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
BCL2L1BCL2-like 1
AVParginine vasopressin
FXNfrataxin
Query geneGeneGene descriptionEdge score
PARK2PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
PSMD10PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
BCL2L1BCL2L1BCL2-like 1
AVPAVParginine vasopressin
FXNFXNfrataxin

Troyanskaya Laboratory - Princeton University