ASD

GO:0006941 striated muscle contraction (44)

GeneInput weightStandardRank
ANK21.0122
DTNA--139
ARHGEF11--705
NOS10.251853
RYR2--1959
RPS6KB1--1521
ALDOA0.2512739
HOMER10.2513402
CASQ2--3574
CAMK2D--4459
SMPX--4615
CHRNA1--4684
GAA--15434
TTN--15620
ADRBK1--6028
KLHL41--6187
PGAM2--6226
MYBPC3--17697
MYL1--7954
TNNC2--8814
ID2B--9924
MAP2K6--10478
VEGFB--11980
ACTC1--112547
TNNI3--112758
TLR4--112795
MYLK2--113626
MAP2K3--13704
MYH6--113823
TNNT1--14867
TNF0.25115243
IKBKB--20225
MYL3--120524
TCAP--122131
MB--22179
PSEN2--23095
ADRB20.25123251
PPP1R13L--23749
TNNC1--123782
TNNT3--124213
TPM1--124247
TNNI2--124646
TAZ--124981
MYL4--25690

Network

GO:0006941

Network
Enrichment
NameDescriptionExternal IDs
ANK2ankyrin 2, neuronal Entrez:287  HGNC: 493  HPRD: 00110  Ensembl: ENSG00000145362 
DTNAdystrobrevin, alpha Entrez:1837  HGNC: 3057  Ensembl: ENSG00000134769  HPRD: 03141 
ARHGEF11Rho guanine nucleotide exchange factor (GEF) 11 Entrez:9826  Ensembl: ENSG00000132694  HPRD: 09302  HGNC: 14580 
NOS1nitric oxide synthase 1 (neuronal) Entrez:4842  HPRD: 01226  HGNC: 7872  Ensembl: ENSG00000089250 
RYR2ryanodine receptor 2 (cardiac) Entrez:6262  Ensembl: ENSG00000198626  HGNC: 10484  HPRD: 01619 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ANK2ankyrin 2, neuronal
DTNAdystrobrevin, alpha
ARHGEF11Rho guanine nucleotide exchange factor (GEF) 11
NOS1nitric oxide synthase 1 (neuronal)
RYR2ryanodine receptor 2 (cardiac)
Query geneGeneGene descriptionEdge score
ANK2ANK2ankyrin 2, neuronal
DTNADTNAdystrobrevin, alpha
ARHGEF11ARHGEF11Rho guanine nucleotide exchange factor (GEF) 11
NOS1NOS1nitric oxide synthase 1 (neuronal)
RYR2RYR2ryanodine receptor 2 (cardiac)

Troyanskaya Laboratory - Princeton University