ASD

GO:0051153 regulation of striated muscle cell differentiation (38)

GeneInput weightStandardRank
PLCB1--148
PIK3R10.251150
MEG3--238
EP300--1318
HDAC4--696
NRG10.251936
SOX9--1970
PROX1--997
BTG1--1000
ADRB1--1057
HDAC5--1950
SHOX2--2767
NOTCH1--12865
TBX3--2958
RBM24--3115
ZFHX3--13201
HDAC9--3228
MUSK--4006
GSK3A--4141
HOPX--4550
SOX8--4609
MYOCD--5907
AGRN0.2516010
BMP4--16499
BOC--6901
ILK--7305
NEU2--8135
NKX2-50.2518486
EDN1--9540
MBNL3--10070
RBM38--11401
MYLK3--12362
MESP1--13805
NMRK2--14041
CAV3--115414
SHH--118571
IGFBP3--22342
FBXO22--23669

Network

GO:0051153

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
EP300E1A binding protein p300 Entrez:2033  Ensembl: ENSG00000100393  HGNC: 3373  HPRD: 04078 
HDAC4histone deacetylase 4 Entrez:9759  Ensembl: ENSG00000068024  HPRD: 05610  HGNC: 14063 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
MEG3maternally expressed 3 (non-protein coding)
EP300E1A binding protein p300
HDAC4histone deacetylase 4
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
MEG3MEG3maternally expressed 3 (non-protein coding)
EP300EP300E1A binding protein p300
HDAC4HDAC4histone deacetylase 4

Troyanskaya Laboratory - Princeton University