ASD

GO:0002832 negative regulation of response to biotic stimulus (12)

GeneInput weightStandardRank
ITCH--2932
TRIB1--3431
IRF3--4175
PRDM1--4368
TNFAIP3--4469
IL2RA--4611
PRDX2--5497
PCBP2--6256
SIGIRR--10327
IFIT1--24398
TARBP2--24667
MICB--25021

Network

GO:0002832

Network
Enrichment
NameDescriptionExternal IDs
ITCHitchy E3 ubiquitin protein ligase Entrez:83737  Ensembl: ENSG00000078747  HGNC: 13890 
TRIB1tribbles homolog 1 (Drosophila) Entrez:10221  HPRD: 09863  Ensembl: ENSG00000173334  HGNC: 16891 
IRF3interferon regulatory factor 3 Entrez:3661  HPRD: 04769  HGNC: 6118  Ensembl: ENSG00000126456 
PRDM1PR domain containing 1, with ZNF domain Entrez:639  HPRD: 04572  Ensembl: ENSG00000057657  HGNC: 9346 
TNFAIP3tumor necrosis factor, alpha-induced protein 3 Entrez:7128  HGNC: 11896  Ensembl: ENSG00000118503  HPRD: 01857 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ITCHitchy E3 ubiquitin protein ligase
TRIB1tribbles homolog 1 (Drosophila)
IRF3interferon regulatory factor 3
PRDM1PR domain containing 1, with ZNF domain
TNFAIP3tumor necrosis factor, alpha-induced protein 3
Query geneGeneGene descriptionEdge score
ITCHITCHitchy E3 ubiquitin protein ligase
TRIB1TRIB1tribbles homolog 1 (Drosophila)
IRF3IRF3interferon regulatory factor 3
PRDM1PRDM1PR domain containing 1, with ZNF domain
TNFAIP3TNFAIP3tumor necrosis factor, alpha-induced protein 3

Troyanskaya Laboratory - Princeton University