ASD

GO:0001707 mesoderm formation (46)

GeneInput weightStandardRank
BMPR2--1281
PAX2--653
SMAD3--823
CHRD--941
NR4A3--1963
BMP7--1137
BMPR1A--1140
LEF1--1499
SMAD1--1872
EPB41L5--2335
PRKAR1A--12428
SMAD2--2694
SRF--2841
NODAL--13149
FOXF1--13518
HAND1--3590
KLF4--3609
AXIN1--14419
HOXA11--4432
WNT3--4613
WNT3A--4747
NF2--15991
TLX2--6047
ACVR1--16054
EYA2--6194
SIX2--6306
BMP4--16499
WNT8A--7814
TBX20--18764
SNAI1--9198
PRKACA--9630
TDGF1P3--9765
FOXC2--10175
EOMES--12952
FOXC1--113793
MESP1--13805
WLS--15707
INHBA--16974
EPHA2--119467
FOXS1--20143
TXNRD1--20757
TRIM15--21614
ECSIT--22627
MESP2--122723
TWSG1--24840
EXT2--125243

Network

GO:0001707

Network
Enrichment
NameDescriptionExternal IDs
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
CHRDchordin Entrez:8646  Ensembl: ENSG00000090539  HGNC: 1949  HPRD: 04592 
NR4A3nuclear receptor subfamily 4, group A, member 3 Entrez:8013  Ensembl: ENSG00000119508  HGNC: 7982  HPRD: 02766 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
PAX2paired box 2
SMAD3SMAD family member 3
CHRDchordin
NR4A3nuclear receptor subfamily 4, group A, member 3
Query geneGeneGene descriptionEdge score
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
PAX2PAX2paired box 2
SMAD3SMAD3SMAD family member 3
CHRDCHRDchordin
NR4A3NR4A3nuclear receptor subfamily 4, group A, member 3

Troyanskaya Laboratory - Princeton University