ASD

GO:0032272 negative regulation of protein polymerization (41)

GeneInput weightStandardRank
MAPRE1--331
STMN2--343
PFN2--551
SLIT2--659
SNCA--1667
CLIP3--730
KANK1--1150
SPTAN1--11287
DMTN--1465
SPTBN4--1647
SPTBN2--11935
TMSB10--2139
CAPZB--2179
ADD2--2388
ADD1--12876
TMSB15A--2947
TMSB15B--3139
SPTB--3478
SPTBN1--3627
INPP5J--3690
CAPZA2--4483
RDX--14697
CAPZA1--4983
SPTBN5--5319
TBCD--5702
TMSB4X--6302
SPTA1--16958
AVIL--7943
CAPZA3--8396
STMN1--9278
SCIN--9620
TWF1--11060
TMSB4Y--13524
TMSB4XP8--14081
TMSB4XP4--17717
CAPG--20663
VIL10.5122243
VILL--22283
TWF2--23010
GSN--124007
TRIOBP--124113

Network

GO:0032272

Network
Enrichment
NameDescriptionExternal IDs
MAPRE1microtubule-associated protein, RP/EB family, member 1 Entrez:22919  HGNC: 6890  HPRD: 04379  Ensembl: ENSG00000101367 
STMN2stathmin-like 2 Entrez:11075  HGNC: 10577  HPRD: 09003  Ensembl: ENSG00000104435 
PFN2profilin 2 Entrez:5217  Ensembl: ENSG00000070087  HGNC: 8882  HPRD: 01451 
SLIT2slit homolog 2 (Drosophila) Entrez:9353  Ensembl: ENSG00000145147  HPRD: 04776  HGNC: 11086 
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAPRE1microtubule-associated protein, RP/EB family, member 1
STMN2stathmin-like 2
PFN2profilin 2
SLIT2slit homolog 2 (Drosophila)
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
Query geneGeneGene descriptionEdge score
MAPRE1MAPRE1microtubule-associated protein, RP/EB family, member 1
STMN2STMN2stathmin-like 2
PFN2PFN2profilin 2
SLIT2SLIT2slit homolog 2 (Drosophila)
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)

Troyanskaya Laboratory - Princeton University