ASD

GO:0050869 negative regulation of B cell activation (22)

GeneInput weightStandardRank
SFRP1--387
ID2--2154
RC3H1--2217
BCL6--2550
ATM--13622
FLT3--14055
PRDM1--4368
TNFAIP3--4469
INHA--4765
NDFIP1--6744
CTLA4--6866
FOXJ1--7628
IL10--19513
SLA2--11651
FOXP3--112457
PAWR--13478
INHBA--16974
SAMSN1--19930
CDKN2A--120587
TNFRSF13B--121223
MNDA--21393
INPP5D--23776

Network

GO:0050869

Network
Enrichment
NameDescriptionExternal IDs
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
ID2inhibitor of DNA binding 2, dominant negative helix-loop-helix protein Entrez:3398  HPRD: 02664  HGNC: 5361  Ensembl: ENSG00000115738 
RC3H1ring finger and CCCH-type domains 1 Entrez:149041  Ensembl: ENSG00000135870  HPRD: 13913  HGNC: 29434 
BCL6B-cell CLL/lymphoma 6 Entrez:604  HGNC: 1001  Ensembl: ENSG00000113916  HPRD: 00180 
ATMataxia telangiectasia mutated Entrez:472  Ensembl: ENSG00000149311  HPRD: 06347  HGNC: 795 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SFRP1secreted frizzled-related protein 1
ID2inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
RC3H1ring finger and CCCH-type domains 1
BCL6B-cell CLL/lymphoma 6
ATMataxia telangiectasia mutated
Query geneGeneGene descriptionEdge score
SFRP1SFRP1secreted frizzled-related protein 1
ID2ID2inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
RC3H1RC3H1ring finger and CCCH-type domains 1
BCL6BCL6B-cell CLL/lymphoma 6
ATMATMataxia telangiectasia mutated

Troyanskaya Laboratory - Princeton University