ASD

GO:0070304 positive regulation of stress-activated protein kinase signaling cascade (44)

GeneInput weightStandardRank
PLCB1--148
MAPK8IP2--418
TGFB2--834
HIPK2--1051
CDC42--1138
SEMA4C--1304
TAOK1--1336
FZD7--1357
TAOK20.2511633
MID1--2259
MAP3K10--2968
WNT5A--3319
TAOK3--3466
WNT16--4117
AXIN1--14419
TRAF4--4556
IL1A--4651
EDA2R--4972
DUSP19--6060
WNT7B--7113
WNT7A--7312
LYN--10336
IL1B--110818
IL26--11645
FGF19--12130
MAP3K11--12938
TLR9--13360
CCL19--14578
TNF0.25115243
SDCBP--19967
F2RL1--19969
MAP4K2--20522
TIRAP--20658
RIPK2--20830
NOD2--121514
CCL21--21829
CCR7--22367
TLR3--22478
TPD52L1--22519
CD27--22836
MYD88--23106
NOD1--23388
CARD9--123577
DUSP22--24825

Network

GO:0070304

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 Entrez:23542  HPRD: 09674  Ensembl: ENSG00000008735  HGNC: 6883 
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
HIPK2homeodomain interacting protein kinase 2 Entrez:28996  HPRD: 06039  HGNC: 14402  Ensembl: ENSG00000064393 
CDC42cell division cycle 42 Entrez:998  HPRD: 00309  HGNC: 1736  Ensembl: ENSG00000070831 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
TGFB2transforming growth factor, beta 2
HIPK2homeodomain interacting protein kinase 2
CDC42cell division cycle 42
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
MAPK8IP2MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
TGFB2TGFB2transforming growth factor, beta 2
HIPK2HIPK2homeodomain interacting protein kinase 2
CDC42CDC42cell division cycle 42

Troyanskaya Laboratory - Princeton University