ASD

GO:0060338 regulation of type I interferon-mediated signaling pathway (32)

GeneInput weightStandardRank
CDC37--2063
IFNA14--2119
IFNA5--2173
IFNA16--2505
IFNA10--2944
IFNA7--3108
WNT5A--3319
IFNA4--3514
IFNA17--3616
HSP90AB1--3924
IFNA13--4164
PTPN1--14239
IFNA21--4570
IFNB1--5250
IFNA1--5952
IFNA6--6742
TYK2--7141
IFNA2--7694
PTPN11--17735
IFNA8--7931
SOCS1--9583
NLRC5--19618
SOCS3--22661
IFNAR1--22765
IFNAR2--22786
JAK1--22851
FADD--23261
MAVS--23348
PTPN6--24184
STAT2--24699
USP18--24779
STAT1--25107

Network

GO:0060338

Network
Enrichment
NameDescriptionExternal IDs
CDC37cell division cycle 37 Entrez:11140  HPRD: 05456  HGNC: 1735  Ensembl: ENSG00000105401 
IFNA14interferon, alpha 14 Entrez:3448  HGNC: 5420  Ensembl: ENSG00000228083  HPRD: 00965 
IFNA5interferon, alpha 5 Entrez:3442  Ensembl: ENSG00000147873  HGNC: 5426  HPRD: 00953 
IFNA16interferon, alpha 16 Entrez:3449  Ensembl: ENSG00000147885  HGNC: 5421  HPRD: 00966 
IFNA10interferon, alpha 10 Entrez:3446  Ensembl: ENSG00000186803  HPRD: 00963  HGNC: 5418 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CDC37cell division cycle 37
IFNA14interferon, alpha 14
IFNA5interferon, alpha 5
IFNA16interferon, alpha 16
IFNA10interferon, alpha 10
Query geneGeneGene descriptionEdge score
CDC37CDC37cell division cycle 37
IFNA14IFNA14interferon, alpha 14
IFNA5IFNA5interferon, alpha 5
IFNA16IFNA16interferon, alpha 16
IFNA10IFNA10interferon, alpha 10

Troyanskaya Laboratory - Princeton University