ASD

GO:0051193 regulation of cofactor metabolic process (14)

GeneInput weightStandardRank
PGAM1--399
SNCA--1667
PDP1--2187
PDPR--3435
PDK3--6222
PDP2--7246
PDHX--8778
PDK2--10195
DLD--110207
PDK4--10696
PDK1--21054
PDHB--22250
DLAT--24135
PDHA1--125033

Network

GO:0051193

Network
Enrichment
NameDescriptionExternal IDs
PGAM1phosphoglycerate mutase 1 (brain) Entrez:5223  Ensembl: ENSG00000171314  HGNC: 8888  HPRD: 01392 
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
PDP1pyruvate dehyrogenase phosphatase catalytic subunit 1 Entrez:54704  HGNC: 9279  HPRD: 16185  Ensembl: ENSG00000164951 
PDPRpyruvate dehydrogenase phosphatase regulatory subunit Entrez:55066  HPRD: 17832  HGNC: 30264  Ensembl: ENSG00000090857 
PDK3pyruvate dehydrogenase kinase, isozyme 3 Entrez:5165  HGNC: 8811  Ensembl: ENSG00000067992  HPRD: 03956 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PGAM1phosphoglycerate mutase 1 (brain)
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
PDP1pyruvate dehyrogenase phosphatase catalytic subunit 1
PDPRpyruvate dehydrogenase phosphatase regulatory subunit
PDK3pyruvate dehydrogenase kinase, isozyme 3
Query geneGeneGene descriptionEdge score
PGAM1PGAM1phosphoglycerate mutase 1 (brain)
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)
PDP1PDP1pyruvate dehyrogenase phosphatase catalytic subunit 1
PDPRPDPRpyruvate dehydrogenase phosphatase regulatory subunit
PDK3PDK3pyruvate dehydrogenase kinase, isozyme 3

Troyanskaya Laboratory - Princeton University