ASD

GO:0042401 cellular biogenic amine biosynthetic process (39)

GeneInput weightStandardRank
AZIN1--376
AMD1--664
SNCA--1667
TGFB2--834
NR4A20.251992
CHRNA70.511837
GATA3--2376
ASMTL--2405
ATP7A--12483
SLC5A7--2703
OAZ1--2789
PAH0.2514423
CHKA--4706
TH0.2514933
AGMAT--5224
AANAT0.2515448
TPH20.2515693
SMOX--5718
DDC0.2515929
ADC--6046
TPH10.2516460
SLC6A30.517659
PNMT--8605
SMS--9865
DBH0.25110495
ASMT0.25110532
CHAT--10603
PRG3--10802
GCH10.25111867
ETNK2--12786
ODC1--113539
HDC--15022
CHKB--17373
SAT1--17894
CHRFAM7A--20694
SLC27A1--21124
PAOX--22526
SRM--24301
ETNK1--25249

Network

GO:0042401

Network
Enrichment
NameDescriptionExternal IDs
AZIN1antizyme inhibitor 1 Entrez:51582  HPRD: 07443  HGNC: 16432  Ensembl: ENSG00000155096 
AMD1adenosylmethionine decarboxylase 1 Entrez:262  HGNC: 457  Ensembl: ENSG00000123505  HPRD: 01622 
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
NR4A2nuclear receptor subfamily 4, group A, member 2 Entrez:4929  HGNC: 7981  HPRD: 03493  Ensembl: ENSG00000153234 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
AZIN1antizyme inhibitor 1
AMD1adenosylmethionine decarboxylase 1
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
TGFB2transforming growth factor, beta 2
NR4A2nuclear receptor subfamily 4, group A, member 2
Query geneGeneGene descriptionEdge score
AZIN1AZIN1antizyme inhibitor 1
AMD1AMD1adenosylmethionine decarboxylase 1
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)
TGFB2TGFB2transforming growth factor, beta 2
NR4A2NR4A2nuclear receptor subfamily 4, group A, member 2

Troyanskaya Laboratory - Princeton University