ASD

GO:0000375 RNA splicing, via transesterification reactions (199)

GeneInput weightStandardRank
NOVA1--25
TRA2B--45
SRPK2--171
SRSF2--194
SCAF11--291
POLR2B--327
SNRPD3--345
SRSF3--369
HNRNPR--377
HNRNPU--378
SF3B1--425
PAPOLA--451
HNRNPH3--474
HNRNPUL1--500
SRSF1--516
DDX5--527
SYNCRIP--670
SFSWAP--680
PABPN1--1697
POLR2E--720
RALY--780
RBM5--784
BCAS2--843
HNRNPK--885
CELF3--929
MBNL1--956
PNN--1078
SRSF5--1085
SNRPE--1101
CDK13--1143
SRSF10--1221
CELF2--1303
DDX1--1332
SF3A2--1383
SRSF4--1403
HNRNPA2B1--1406
SRRM2--1438
SRSF9--1459
PRPF8--11509
LSM3--1525
PTBP2--1558
POLR2A--1630
TRA2A--1649
HNRNPA3--1666
RBMX--1730
SFPQ--1771
PSIP1--1794
DHX9--1846
SNRPG--1855
SRRM1--1865
GTF2F1--1876
PTBP1--1894
HNRNPC--1945
YTHDC1--1961
PCBP1--1972
CPSF1--1994
HNRNPA1--1999
CPSF7--2132
CELF4--2224
CELF1--2232
CACTIN--2239
SRSF11--2370
HNRNPD--2384
PCF11--2427
SF1--2557
MAGOH--2595
HNRNPA0--2637
RBM8A--12710
KHSRP--2727
SNRNP200--12747
PRPF6--2849
SNRPB--2943
CDC5L--2971
RNPS1--2983
HNRNPM--3073
POLR2J--3075
FUS--13121
SRSF12--3143
DDX39B--3165
SRSF7--3293
SNRPF--3566
AQR--3581
PRPF4B--3833
SF3A1--3851
POLR2L--3908
SNRNP70--3928
LSM7--3961
SNW1--4235
WBP4--4351
SUGP1--4480
CDC40--4638
CRNKL1--4816
CCAR1--5065
HNRNPH2--5527
SNRPB2--5669
DHX38--5688
SF3B4--5707
RBM22--5898
ZCCHC8--6015
MPHOSPH10--6020
U2AF1--6084
PCBP2--6256
XAB2--6412
GEMIN8--6493
POLR2G--6511
SF3B2--6524
SNRPA1--6612
DDX41--6619
HNRNPH1--6659
POLR2K--6853
SRSF6--7591
EIF4A3--7597
SNRPA--7748
DDX39A--7965
PPIH--8076
SNRPD2--8079
DNAJC8--8752
PABPC1--9200
POLR2I--9926
PRPF3--110046
LSM2--10522
DHX8--11248
POLR2F--11417
RSRC1--11765
LSM1--12104
HNRNPL--12447
DGCR14--12684
SF3B5--13264
SNRPC--13480
CD2BP2--13806
PPWD1--14127
TXNL4A--14329
DDX23--15217
U2AF2--15462
ISY1--15675
SLU7--15784
SMNDC1--16907
WDR83--19624
CSTF3--19828
PLRG1--19849
SMC1A--19955
GEMIN7--20050
FRG1--20336
SKIV2L2--20490
ZRSR2--20730
SART1--20962
GPATCH1--20970
CWC22--20990
HNRNPF--21090
POLR2C--21170
PHAX--21296
NAA38--21307
UPF3B--21339
CLNS1A--21544
PRPF31--121690
DHX35--21731
NHP2L1--21743
PHF5A--21873
ALYREF--21975
NUDT21--22164
CPSF2--22263
SF3B3--22281
TFIP11--22295
EFTUD2--22821
PRMT7--22847
SNRPD1--22863
PRPF19--22991
CWC15--23021
SYF2--23192
TGS1--23201
YBX1--23203
NCBP2--23216
SNUPN--23274
CWC27--23320
CSTF1--23384
POLR2H--23670
PPIL3--23716
GTF2F2--23723
PRPF4--23787
SMN1--123959
USP39--24080
CLP1--24100
CPSF3--24383
SNRNP40--24473
SMN2--124729
DBR1--24797
SF3A3--24887
GEMIN6--24931
DDX20--24949
PPIE--25106
PPIL1--25189
GEMIN2--25309
POLR2D--25479
NCBP1--25523
GEMIN5--25530
PRMT5--25692
CSTF2--25704
GEMIN4--25724
WDR77--25820

Network

GO:0000375

Network
Enrichment
NameDescriptionExternal IDs
NOVA1neuro-oncological ventral antigen 1 Entrez:4857  HPRD: 03693  Ensembl: ENSG00000139910  HGNC: 7886 
TRA2Btransformer 2 beta homolog (Drosophila) Entrez:6434  HGNC: 10781  HPRD: 04097 
SRPK2SRSF protein kinase 2 Entrez:6733  HPRD: 04280  Ensembl: ENSG00000135250  HGNC: 11306 
SRSF2serine/arginine-rich splicing factor 2 Entrez:6427  HPRD: 02888  HGNC: 10783  Ensembl: ENSG00000161547 
SCAF11SR-related CTD-associated factor 11 Entrez:9169  HGNC: 10784  HPRD: 04720 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NOVA1neuro-oncological ventral antigen 1
TRA2Btransformer 2 beta homolog (Drosophila)
SRPK2SRSF protein kinase 2
SRSF2serine/arginine-rich splicing factor 2
SCAF11SR-related CTD-associated factor 11
Query geneGeneGene descriptionEdge score
NOVA1NOVA1neuro-oncological ventral antigen 1
TRA2BTRA2Btransformer 2 beta homolog (Drosophila)
SRPK2SRPK2SRSF protein kinase 2
SRSF2SRSF2serine/arginine-rich splicing factor 2
SCAF11SCAF11SR-related CTD-associated factor 11

Troyanskaya Laboratory - Princeton University