ASD

GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal (30)

GeneInput weightStandardRank
RPS6KA20.251689
ADRB1--1057
DRD50.2511103
EDN3--11577
ADRA1A--1858
NOX1--1924
AGTR20.2511955
ADRB3--12953
NKX2-1--4142
DRD30.2514349
CORIN--4683
ADRA1B0.2514946
AGTR1--16275
REN--17086
CYBA--17322
ADRA1D--7837
EDN1--9540
HSD11B2--9892
ACE--10304
ACE2--11390
PCSK5--13062
AGT--113305
CYP11B2--13660
EDN2--18677
ECE1--120540
NOS3--20542
SOD2--22687
ADRB20.25123251
TPM1--124247
ATP6AP2--25361

Network

GO:0003044

Network
Enrichment
NameDescriptionExternal IDs
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2 Entrez:6196  Ensembl: ENSG00000071242  HPRD: 03403  HGNC: 10431 
ADRB1adrenoceptor beta 1 Entrez:153  HGNC: 285  Ensembl: ENSG00000043591  HPRD: 00181 
DRD5dopamine receptor D5 Entrez:1816  HGNC: 3026  Ensembl: ENSG00000169676  HPRD: 00542 
EDN3endothelin 3 Entrez:1908  HGNC: 3178  Ensembl: ENSG00000124205  HPRD: 00570 
ADRA1Aadrenoceptor alpha 1A Entrez:148  HGNC: 277  Ensembl: ENSG00000120907  HPRD: 00081 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2
ADRB1adrenoceptor beta 1
DRD5dopamine receptor D5
EDN3endothelin 3
ADRA1Aadrenoceptor alpha 1A
Query geneGeneGene descriptionEdge score
RPS6KA2RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2
ADRB1ADRB1adrenoceptor beta 1
DRD5DRD5dopamine receptor D5
EDN3EDN3endothelin 3
ADRA1AADRA1Aadrenoceptor alpha 1A

Troyanskaya Laboratory - Princeton University