ASD

GO:0017145 stem cell division (18)

GeneInput weightStandardRank
PAFAH1B10.25174
FGFR2--1237
LRP6--279
TGFB2--834
LEF1--1499
VANGL2--1793
FGFR1--2262
NOTCH1--12865
BMI1--3300
NUMBL--3618
TIAL1--4048
WNT3A--4747
WNT7A--7312
NUMB--7848
HOXB4--10579
CDKN2A--120587
WWTR1--24317
ASPM--124942

Network

GO:0017145

Network
Enrichment
NameDescriptionExternal IDs
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Entrez:5048  HGNC: 8574  HPRD: 03329  Ensembl: ENSG00000007168 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
LEF1lymphoid enhancer-binding factor 1 Entrez:51176  HGNC: 6551  Ensembl: ENSG00000138795  HPRD: 01075 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
FGFR2fibroblast growth factor receptor 2
LRP6low density lipoprotein receptor-related protein 6
TGFB2transforming growth factor, beta 2
LEF1lymphoid enhancer-binding factor 1
Query geneGeneGene descriptionEdge score
PAFAH1B1PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
FGFR2FGFR2fibroblast growth factor receptor 2
LRP6LRP6low density lipoprotein receptor-related protein 6
TGFB2TGFB2transforming growth factor, beta 2
LEF1LEF1lymphoid enhancer-binding factor 1

Troyanskaya Laboratory - Princeton University