ASD

GO:0060402 calcium ion transport into cytosol (29)

GeneInput weightStandardRank
HTR2C0.25162
HTR2A0.251121
PRKCE--204
SLC8A2--334
JPH3--580
CACNA1C--1807
RYR2--1959
SLC8A1--1529
ADRA1A--1858
FKBP1B--2346
JPH1--3027
JPH4--3380
DRD20.2513749
SLC8A3--4131
XCR1--6470
HTR2B--6992
XCL1--7819
GLP1R--9893
FGF2--13150
RYR1--113799
CCL19--14578
JPH2--18890
BBC3--20534
PTPRC--21546
ITPR3--21697
CCL21--21829
CCR7--22367
IBTK--22790
LCK--24753

Network

GO:0060402

Network
Enrichment
NameDescriptionExternal IDs
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Entrez:3358  HGNC: 5295  HPRD: 02429  Ensembl: ENSG00000147246 
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HPRD: 01638  Ensembl: ENSG00000102468  HGNC: 5293 
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
SLC8A2solute carrier family 8 (sodium/calcium exchanger), member 2 Entrez:6543  Ensembl: ENSG00000118160  HGNC: 11069  HPRD: 15990 
JPH3junctophilin 3 Entrez:57338  Ensembl: ENSG00000154118  HGNC: 14203  HPRD: 05589 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
PRKCEprotein kinase C, epsilon
SLC8A2solute carrier family 8 (sodium/calcium exchanger), member 2
JPH3junctophilin 3
Query geneGeneGene descriptionEdge score
HTR2CHTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
PRKCEPRKCEprotein kinase C, epsilon
SLC8A2SLC8A2solute carrier family 8 (sodium/calcium exchanger), member 2
JPH3JPH3junctophilin 3

Troyanskaya Laboratory - Princeton University