ASD

GO:0010700 negative regulation of norepinephrine secretion (6)

GeneInput weightStandardRank
ADRA2A0.2511399
P2RY1--4342
ADRA2C--8551
ADRA2B--10119
C5--122004
PTGS1--24613

Network

GO:0010700

Network
Enrichment
NameDescriptionExternal IDs
ADRA2Aadrenoceptor alpha 2A Entrez:150  HGNC: 281  HPRD: 00078  Ensembl: ENSG00000150594 
P2RY1purinergic receptor P2Y, G-protein coupled, 1 Entrez:5028  HGNC: 8539  Ensembl: ENSG00000169860  HPRD: 03103 
ADRA2Cadrenoceptor alpha 2C Entrez:152  Ensembl: ENSG00000184160  HPRD: 00085  HGNC: 283 
ADRA2Badrenoceptor alpha 2B Entrez:151  HPRD: 00086  HGNC: 282  Ensembl: ENSG00000222040 
C5complement component 5 Entrez:727  HGNC: 1331  Ensembl: ENSG00000106804  HPRD: 00405 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ADRA2Aadrenoceptor alpha 2A
P2RY1purinergic receptor P2Y, G-protein coupled, 1
ADRA2Cadrenoceptor alpha 2C
ADRA2Badrenoceptor alpha 2B
C5complement component 5
Query geneGeneGene descriptionEdge score
ADRA2AADRA2Aadrenoceptor alpha 2A
P2RY1P2RY1purinergic receptor P2Y, G-protein coupled, 1
ADRA2CADRA2Cadrenoceptor alpha 2C
ADRA2BADRA2Badrenoceptor alpha 2B
C5C5complement component 5

Troyanskaya Laboratory - Princeton University