ASD

GO:0045666 positive regulation of neuron differentiation (52)

GeneInput weightStandardRank
NRCAM0.25169
SOX11--96
NEUROD2--98
NEUROD1--1127
TCF4--337
MAP1B--403
ASCL1--413
SALL1--506
SPAG9--558
BDNF0.251791
ACTR3--803
RGS6--805
NKX2-2--1120
BMP7--1137
HOXD3--1195
ZEB1--11901
PHOX2B--1917
FOXA1--1990
GDF6--12291
RHOA--2292
FOXA2--2645
NEUROG2--2989
FEZ1--3035
TGIF2--3180
TGIF1--13264
CDON--3487
ITGB1--3903
BMP6--4358
NEUROG10.2514644
NKX6-1--4665
TCF3--6420
BMP4--16499
GDF7--6682
LIN28A--7070
IRX3--7476
CXCL12--7802
NKX2-50.2518486
ADRA2C--8551
VWC2--8879
NBL1--9632
TRIM320.2519794
ADRA2B--10119
NEUROG3--10352
ATOH1--11336
HEYL--12571
IL6--112695
IFNG--112827
DNMT3B--14663
FEZF10.25116009
SHH--118571
EPO--20282
CCL5--23042

Network

GO:0045666

Network
Enrichment
NameDescriptionExternal IDs
NRCAMneuronal cell adhesion molecule Entrez:4897  Ensembl: ENSG00000091129  HGNC: 7994  HPRD: 07207 
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
NEUROD2neuronal differentiation 2 Entrez:4761  HPRD: 03429  HGNC: 7763 
NEUROD1neuronal differentiation 1 Entrez:4760  HPRD: 03428  HGNC: 7762  Ensembl: ENSG00000162992 
TCF4transcription factor 4 Entrez:6925  Ensembl: ENSG00000196628  HPRD: 03780  HGNC: 11634 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NRCAMneuronal cell adhesion molecule
SOX11SRY (sex determining region Y)-box 11
NEUROD2neuronal differentiation 2
NEUROD1neuronal differentiation 1
TCF4transcription factor 4
Query geneGeneGene descriptionEdge score
NRCAMNRCAMneuronal cell adhesion molecule
SOX11SOX11SRY (sex determining region Y)-box 11
NEUROD2NEUROD2neuronal differentiation 2
NEUROD1NEUROD1neuronal differentiation 1
TCF4TCF4transcription factor 4

Troyanskaya Laboratory - Princeton University