ASD

GO:0010811 positive regulation of cell-substrate adhesion (44)

GeneInput weightStandardRank
PRKCE--204
SFRP1--387
GSK3B--427
EDIL3--654
TSC10.251790
SMAD3--823
SPOCK2--1166
CDH13--1692
CDK6--1795
COL8A1--2181
EPB41L5--2335
SMOC2--3216
ABI3BP--3235
FOXF1--13518
ITGB1--3903
NDNF--4408
KDR0.2514854
EGFL6--5256
EGFLAM--5373
ARL2--5930
NPNT--6188
CSF1--6542
UTRN--6684
VIT--7016
ILK--7305
VWC2--8879
PTPRJ--19136
SPP1--12442
VTN--13271
PLEKHA2--13465
RELL2--14624
JAK2--119561
ECM2--20221
CCDC80--20347
CCL21--21829
ITGA6--22166
CCR7--22367
CYR61--22574
SDC4--23067
HSD17B12--23325
CD36--23662
NID1--23834
FBLN2--24427
EMILIN1--24941

Network

GO:0010811

Network
Enrichment
NameDescriptionExternal IDs
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
GSK3Bglycogen synthase kinase 3 beta Entrez:2932  Ensembl: ENSG00000082701  HPRD: 05418  HGNC: 4617 
EDIL3EGF-like repeats and discoidin I-like domains 3 Entrez:10085  HPRD: 09350  HGNC: 3173  Ensembl: ENSG00000164176 
TSC1tuberous sclerosis 1 Entrez:7248  Ensembl: ENSG00000165699  HGNC: 12362  HPRD: 05594 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PRKCEprotein kinase C, epsilon
SFRP1secreted frizzled-related protein 1
GSK3Bglycogen synthase kinase 3 beta
EDIL3EGF-like repeats and discoidin I-like domains 3
TSC1tuberous sclerosis 1
Query geneGeneGene descriptionEdge score
PRKCEPRKCEprotein kinase C, epsilon
SFRP1SFRP1secreted frizzled-related protein 1
GSK3BGSK3Bglycogen synthase kinase 3 beta
EDIL3EDIL3EGF-like repeats and discoidin I-like domains 3
TSC1TSC1tuberous sclerosis 1

Troyanskaya Laboratory - Princeton University