ASD

GO:0002027 regulation of heart rate (29)

GeneInput weightStandardRank
PIK3R10.251150
CACNA1G0.251443
TAC10.251726
CALCA--1013
ADRB1--1057
EDN3--11577
CHRNA70.511837
ADRA1A--1858
AGTR20.2511955
FKBP1B--2346
SEMA3A--3494
TACR3--3564
DRD20.2513749
AVPR1A0.513803
IRX5--4848
ADRA1B0.2514946
AVPR1B0.2518546
EDN1--9540
EPAS1--10869
OXT0.25111176
PMCH--12542
MYH6--113823
EDN2--18677
SREBF1--19464
MYH7--120417
CHRFAM7A--20694
ADM--21106
TPM1--124247
ADA0.5124751

Network

GO:0002027

Network
Enrichment
NameDescriptionExternal IDs
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit Entrez:8913  HPRD: 04961  HGNC: 1394  Ensembl: ENSG00000006283 
TAC1tachykinin, precursor 1 Entrez:6863  HGNC: 11517  HPRD: 08876  Ensembl: ENSG00000006128 
CALCAcalcitonin-related polypeptide alpha Entrez:796  HGNC: 1437  HPRD: 00238  Ensembl: ENSG00000110680 
ADRB1adrenoceptor beta 1 Entrez:153  HGNC: 285  Ensembl: ENSG00000043591  HPRD: 00181 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit
TAC1tachykinin, precursor 1
CALCAcalcitonin-related polypeptide alpha
ADRB1adrenoceptor beta 1
Query geneGeneGene descriptionEdge score
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
CACNA1GCACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit
TAC1TAC1tachykinin, precursor 1
CALCACALCAcalcitonin-related polypeptide alpha
ADRB1ADRB1adrenoceptor beta 1

Troyanskaya Laboratory - Princeton University