ASD

GO:0061371 determination of heart left/right asymmetry (35)

GeneInput weightStandardRank
LRP6--279
ZIC3--1789
SMAD3--823
HIF1A--1075
MIB10.2511153
VANGL2--1793
SRF--2841
C2CD3--2994
NODAL--13149
WNT5A--3319
HAND1--3590
SOX17--4024
WNT3A--4747
HAND2--5589
IHH--17160
FOXJ1--7628
NKX2-50.2518486
TBX20--18764
LBX1--9134
SUFU--19372
BBS4--110131
SMO0.25110504
BBS5--110945
FOXH1--10963
GATA4--112466
MESP1--13805
GJA10.25113867
MKKS--114510
IFT52--16599
PSEN1--18523
SHH--118571
SOX18--20812
BBS7--122032
SETDB20.25122691
ENG--124746

Network

GO:0061371

Network
Enrichment
NameDescriptionExternal IDs
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
ZIC3Zic family member 3 Entrez:7547  HGNC: 12874  HPRD: 02225  Ensembl: ENSG00000156925 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
MIB1mindbomb E3 ubiquitin protein ligase 1 Entrez:57534  HPRD: 06660  Ensembl: ENSG00000101752  HGNC: 21086 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
LRP6low density lipoprotein receptor-related protein 6
ZIC3Zic family member 3
SMAD3SMAD family member 3
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
MIB1mindbomb E3 ubiquitin protein ligase 1
Query geneGeneGene descriptionEdge score
LRP6LRP6low density lipoprotein receptor-related protein 6
ZIC3ZIC3Zic family member 3
SMAD3SMAD3SMAD family member 3
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
MIB1MIB1mindbomb E3 ubiquitin protein ligase 1

Troyanskaya Laboratory - Princeton University