ASD

GO:0045638 negative regulation of myeloid cell differentiation (51)

GeneInput weightStandardRank
SFRP1--387
TOB2--880
CALCA--1013
RUNX1--11449
CARTPT0.2511957
STAT5B--2593
ZFP36--3314
HOXA7--3411
RARA0.2513695
NME2--3712
LRRC17--3841
PRMT1--4008
RBM15--4247
ZBTB16--4249
PRDM16--4345
INHA--4765
THOC5--4981
HOXA5--5132
HIST1H4C--5314
HIST1H4F--5483
NFKBIA--5569
ADIPOQ0.2516032
IL4--6852
HIST1H4B--7028
GPR55--8693
HIST1H4A--8765
HIST1H4E--8846
CTNNB10.519066
HIST4H4--9288
HIST1H4I--9593
LDB1--10693
MAFB--10783
HIST1H4K--11490
ZNF675--11676
HIST1H4H--11835
HIST2H4B--12217
HIST1H4L--12237
TLR4--112795
NME1--113556
LMO2--14404
C1QC--15231
HIST1H4D--15824
INHBA--16974
PF4--17209
STAT5A--21176
HIST1H4J--21464
TLR3--22478
HIST2H4A--22838
INPP5D--23776
NME1-NME2--25082
FSTL3--25154

Network

GO:0045638

Network
Enrichment
NameDescriptionExternal IDs
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
TOB2transducer of ERBB2, 2 Entrez:10766  HGNC: 11980  HPRD: 09583  Ensembl: ENSG00000183864 
CALCAcalcitonin-related polypeptide alpha Entrez:796  HGNC: 1437  HPRD: 00238  Ensembl: ENSG00000110680 
RUNX1runt-related transcription factor 1 Entrez:861  HPRD: 01043  Ensembl: ENSG00000159216  HGNC: 10471 
CARTPTCART prepropeptide Entrez:9607  HGNC: 24323  HPRD: 04006  Ensembl: ENSG00000164326 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SFRP1secreted frizzled-related protein 1
TOB2transducer of ERBB2, 2
CALCAcalcitonin-related polypeptide alpha
RUNX1runt-related transcription factor 1
CARTPTCART prepropeptide
Query geneGeneGene descriptionEdge score
SFRP1SFRP1secreted frizzled-related protein 1
TOB2TOB2transducer of ERBB2, 2
CALCACALCAcalcitonin-related polypeptide alpha
RUNX1RUNX1runt-related transcription factor 1
CARTPTCARTPTCART prepropeptide

Troyanskaya Laboratory - Princeton University