ASD

GO:0010944 negative regulation of transcription by competitive promoter binding (5)

GeneInput weightStandardRank
SMAD7--1192
TFAP2A--12923
OVOL2--10428
HHEX--19523
PHB--125747

Network

GO:0010944

Network
Enrichment
NameDescriptionExternal IDs
SMAD7SMAD family member 7 Entrez:4092  HPRD: 04241  HGNC: 6773  Ensembl: ENSG00000101665 
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha) Entrez:7020  Ensembl: ENSG00000137203  HGNC: 11742  HPRD: 00128 
OVOL2ovo-like 2 (Drosophila) Entrez:58495  HGNC: 15804  Ensembl: ENSG00000125850  HPRD: 15780 
HHEXhematopoietically expressed homeobox Entrez:3087  HGNC: 4901  HPRD: 06829 
PHBprohibitin Entrez:5245  HGNC: 8912  HPRD: 01454  Ensembl: ENSG00000167085 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SMAD7SMAD family member 7
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
OVOL2ovo-like 2 (Drosophila)
HHEXhematopoietically expressed homeobox
PHBprohibitin
Query geneGeneGene descriptionEdge score
SMAD7SMAD7SMAD family member 7
TFAP2ATFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
OVOL2OVOL2ovo-like 2 (Drosophila)
HHEXHHEXhematopoietically expressed homeobox
PHBPHBprohibitin

Troyanskaya Laboratory - Princeton University