GO:0042738 exogenous drug catabolic process (9)

GeneInput weightStandardRank
NOS10.251853
CYP2A6--12792
CYP2C8--3090
CYP2C9--3660
CYP2C19--4815
CYP2B6--5346
CYP1A2--6074
NR1I2--9659
CYP3A4--9925

Network

GO:0042738

Network
Enrichment
NameDescriptionExternal IDs
NOS1nitric oxide synthase 1 (neuronal) Entrez:4842  HPRD: 01226  HGNC: 7872  Ensembl: ENSG00000089250 
CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6 Entrez:1548  Ensembl: ENSG00000255974  HPRD: 00420  HGNC: 2610 
CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 8 Entrez:1558  HGNC: 2622  Ensembl: ENSG00000138115  HPRD: 03083 
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 9 Entrez:1559  HGNC: 2623  HPRD: 03084  Ensembl: ENSG00000138109 
CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 19 Entrez:1557  HGNC: 2621  HPRD: 00486 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NOS1nitric oxide synthase 1 (neuronal)
CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 19
Query geneGeneGene descriptionEdge score
NOS1NOS1nitric oxide synthase 1 (neuronal)
CYP2A6CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C8CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2C19CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 19