ASD

GO:0008589 regulation of smoothened signaling pathway (38)

GeneInput weightStandardRank
FGFR2--1237
FGF9--262
SFRP1--387
RUNX2--1480
SALL1--506
ZIC1--939
CHRD--941
PTCH1--1972
SALL3--1487
OTX2--11916
PRRX1--2125
FGFR3--12640
SHOX2--2767
TULP3--2770
HHIP--2786
C2CD3--2994
SERPINE2--3708
FGF10--14532
POR0.2515184
GLI1--6241
GLI3--16261
GAS1--6937
WNT7B--7113
IHH--17160
GPC3--18430
CTNNA1--9331
SUFU--19372
CD3E--9680
KIF7--19825
SMO0.25110504
FUZ--12978
WNT9A--13365
SHH--118571
RAB23--20831
STK36--21217
RPGRIP1L--21472
DISP1--22983
PRRX2--23936

Network

GO:0008589

Network
Enrichment
NameDescriptionExternal IDs
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
FGF9fibroblast growth factor 9 Entrez:2254  HPRD: 02951  HGNC: 3687  Ensembl: ENSG00000102678 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
RUNX2runt-related transcription factor 2 Entrez:860  Ensembl: ENSG00000124813  HGNC: 10472  HPRD: 02566 
SALL1sal-like 1 (Drosophila) Entrez:6299  HGNC: 10524  Ensembl: ENSG00000103449  HPRD: 03742 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FGFR2fibroblast growth factor receptor 2
FGF9fibroblast growth factor 9
SFRP1secreted frizzled-related protein 1
RUNX2runt-related transcription factor 2
SALL1sal-like 1 (Drosophila)
Query geneGeneGene descriptionEdge score
FGFR2FGFR2fibroblast growth factor receptor 2
FGF9FGF9fibroblast growth factor 9
SFRP1SFRP1secreted frizzled-related protein 1
RUNX2RUNX2runt-related transcription factor 2
SALL1SALL1sal-like 1 (Drosophila)

Troyanskaya Laboratory - Princeton University