ASD

GO:0046058 cAMP metabolic process (26)

GeneInput weightStandardRank
ADCY2--175
PDE4D--348
ADCY10.251466
GNAL--1177
PDE4A--1260
GNAS--11842
ADCY9--1850
PDE2A--1938
PTHLH--11993
PDE4B--2178
PDE1B--2534
PDE11A--2780
ADCY8--2785
ADCY6--2877
PDE4C--3021
ADCY10--3117
PDE3A--3628
PDE3B--3819
ADCY5--4295
ADCY3--5755
PTH--6947
ADORA2A0.2518408
ADCY4--9091
UCN2--11559
ADM--21106
ADCY7--25408

Network

GO:0046058

Network
Enrichment
NameDescriptionExternal IDs
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
PDE4Dphosphodiesterase 4D, cAMP-specific Entrez:5144  HPRD: 02530  HGNC: 8783  Ensembl: ENSG00000113448 
ADCY1adenylate cyclase 1 (brain) Entrez:107  HGNC: 232  HPRD: 00053  Ensembl: ENSG00000164742 
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type Entrez:2774  HGNC: 4388  Ensembl: ENSG00000141404  HPRD: 00758 
PDE4Aphosphodiesterase 4A, cAMP-specific Entrez:5141  HPRD: 02527  HGNC: 8780  Ensembl: ENSG00000065989 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ADCY2adenylate cyclase 2 (brain)
PDE4Dphosphodiesterase 4D, cAMP-specific
ADCY1adenylate cyclase 1 (brain)
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
PDE4Aphosphodiesterase 4A, cAMP-specific
Query geneGeneGene descriptionEdge score
ADCY2ADCY2adenylate cyclase 2 (brain)
PDE4DPDE4Dphosphodiesterase 4D, cAMP-specific
ADCY1ADCY1adenylate cyclase 1 (brain)
GNALGNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
PDE4APDE4Aphosphodiesterase 4A, cAMP-specific

Troyanskaya Laboratory - Princeton University